Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases

Detalhes bibliográficos
Autor(a) principal: Gripp, Carmem Beatriz Wagner Giacoia
Data de Publicação: 2011
Outros Autores: Sales, Anna Maria, Nery, José Augusto da Costa, Oliveira, Joanna Reis Santos de, Oliveira, Ariane Leite de, Sarno, Euzenir Nunes, Morgado, Mariza Gonçalves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15856
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.
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spelling Gripp, Carmem Beatriz Wagner GiacoiaSales, Anna MariaNery, José Augusto da CostaOliveira, Joanna Reis Santos deOliveira, Ariane Leite deSarno, Euzenir NunesMorgado, Mariza Gonçalves2016-09-20T11:39:17Z2016-09-20T11:39:17Z2011GRIPP, Carmem Beatriz Wagner Giacoia; et al. Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/Leprosy cases. Plos One, v.6, n.12, e28735, 8p, Dec. 2011.1932-6203https://www.arca.fiocruz.br/handle/icict/1585610.1371/journal.pone.0028735engPublic Library of ScienceHIVHanseníaseCoinfecção por HIVMycobacterium lepraeSíndrome inflamatória de reconstituição imunológicaHIVLeprosyHIV coinfectionMycobacterium lepraeImmune reconstitution inflammatory syndromeEvaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy casesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, BrasilIt is now evident that HAART-associated immunological improvement often leads to a variety of new clinical manifestations, collectively termed immune reconstitution inflammatory syndrome, or IRIS. This phenomenon has already been described in cases of HIV coinfection with Mycobacterium leprae, most of them belonging to the tuberculoid spectrum of leprosy disease, as observed in leprosy reversal reaction (RR). However, the events related to the pathogenesis of this association need to be clarified. This study investigated the immunological profile of HIV/leprosy patients, with special attention to the cellular activation status, to better understand the mechanisms related to IRIS/RR immunopathogenesis, identifying any potential biomarkers for IRIS/RR intercurrence.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15856/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcarmem_gripp_etal_IOC_2011.pdfcarmem_gripp_etal_IOC_2011.pdfapplication/pdf594823https://www.arca.fiocruz.br/bitstream/icict/15856/2/carmem_gripp_etal_IOC_2011.pdf7e71df81c626f325c4645c69f3cd04bfMD52TEXTcarmem_gripp_etal_IOC_2011.pdf.txtcarmem_gripp_etal_IOC_2011.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
title Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
spellingShingle Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
Gripp, Carmem Beatriz Wagner Giacoia
HIV
Hanseníase
Coinfecção por HIV
Mycobacterium leprae
Síndrome inflamatória de reconstituição imunológica
HIV
Leprosy
HIV coinfection
Mycobacterium leprae
Immune reconstitution inflammatory syndrome
title_short Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
title_full Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
title_fullStr Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
title_full_unstemmed Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
title_sort Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/leprosy cases
author Gripp, Carmem Beatriz Wagner Giacoia
author_facet Gripp, Carmem Beatriz Wagner Giacoia
Sales, Anna Maria
Nery, José Augusto da Costa
Oliveira, Joanna Reis Santos de
Oliveira, Ariane Leite de
Sarno, Euzenir Nunes
Morgado, Mariza Gonçalves
author_role author
author2 Sales, Anna Maria
Nery, José Augusto da Costa
Oliveira, Joanna Reis Santos de
Oliveira, Ariane Leite de
Sarno, Euzenir Nunes
Morgado, Mariza Gonçalves
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gripp, Carmem Beatriz Wagner Giacoia
Sales, Anna Maria
Nery, José Augusto da Costa
Oliveira, Joanna Reis Santos de
Oliveira, Ariane Leite de
Sarno, Euzenir Nunes
Morgado, Mariza Gonçalves
dc.subject.other.pt_BR.fl_str_mv HIV
Hanseníase
Coinfecção por HIV
Mycobacterium leprae
Síndrome inflamatória de reconstituição imunológica
topic HIV
Hanseníase
Coinfecção por HIV
Mycobacterium leprae
Síndrome inflamatória de reconstituição imunológica
HIV
Leprosy
HIV coinfection
Mycobacterium leprae
Immune reconstitution inflammatory syndrome
dc.subject.en.pt_BR.fl_str_mv HIV
Leprosy
HIV coinfection
Mycobacterium leprae
Immune reconstitution inflammatory syndrome
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de AIDS e Imunologia Molecular. Rio de Janeiro, RJ, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2016-09-20T11:39:17Z
dc.date.available.fl_str_mv 2016-09-20T11:39:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GRIPP, Carmem Beatriz Wagner Giacoia; et al. Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/Leprosy cases. Plos One, v.6, n.12, e28735, 8p, Dec. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15856
dc.identifier.issn.pt_BR.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0028735
identifier_str_mv GRIPP, Carmem Beatriz Wagner Giacoia; et al. Evaluation of cellular phenotypes implicated in immunopathogenesis and monitoring immune reconstitution inflammatory syndrome in HIV/Leprosy cases. Plos One, v.6, n.12, e28735, 8p, Dec. 2011.
1932-6203
10.1371/journal.pone.0028735
url https://www.arca.fiocruz.br/handle/icict/15856
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/15856/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/15856/2/carmem_gripp_etal_IOC_2011.pdf
https://www.arca.fiocruz.br/bitstream/icict/15856/3/carmem_gripp_etal_IOC_2011.pdf.txt
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