Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/18824 |
Resumo: | Universidade Federal Fluminense. Instituto Biomédico. Disciplina de Doenças Infecciosas e Parasitárias. Niterói, RJ, Brasil. |
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Azevedo, Kátia Martins Lopes deSetúbal, SérgioCamacho, Luiz Antonio BastosGarcia, Rita de Cássia Nasser CubelSiqueira, Marilda Agudo Mendonça Teixeira dePereira, Renata Freire AlvesOliveira, Solange Artimos de2017-05-11T16:05:09Z2017-05-11T16:05:09Z2012AZEVEDO, Kátia Martins Lopes de; Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients. Mem Inst Oswaldo Cruz, v.107, n.3, p.356-361, May 2012.0074-0276https://www.arca.fiocruz.br/handle/icict/188241678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzParvovirus B19 HumanoAnemiaSoroconversãoInfecção por HIVhuman parvovirus B19seroconversionHIV infectionanaemiaParvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Fluminense. Instituto Biomédico. Disciplina de Doenças Infecciosas e Parasitárias. Niterói, RJ, Brasil.Universidade Federal Fluminense. Instituto Biomédico. Disciplina de Doenças Infecciosas e Parasitárias. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Epidemiologia. Rio de Janeiro, RJ. Brasil.Universidade Federal Fluminense. Instituto Biomédico. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Universidade do Grande Rio. Escola de Farmácia. Duque de Caxias, RJ, Brasil.Universidade Federal Fluminense. Instituto Biomédico. Disciplina de Doenças Infecciosas e Parasitárias. Niterói, RJ, Brasil.Erythrovirus B19 (B19V) infection may cause red cell aplasia in patients infected with human immunodeficiency virus (HIV). The introduction of highly active antiretroviral therapy (HAART) has improved the immune function of these patients by modifying the course of B19V infection. The purpose of this study was to estimate the frequency of B19 seroconversion in a cohort of HIV-infected patients and evaluate the occurrence of B19V-related anaemia during the seroconversion period. Adult HIV-infected patients were studied at a public hospital in Niterói, state of Rio de Janeiro, Brazil. IgG and IgM antibodies against B19V were detected by an enzyme-linked immunosorbent assay and B19 viraemia was assayed by polymerase chain reaction. Medical records were reviewed for any clinical evaluation of anaemia. Seroconversion was detected in 31.8% of the 88 individuals who began the study as anti-B19V IgG-negative. No clinical manifestations of B19V infection were detected during the period of seroconversion. Patients who seroconverted were 5.40 times more likely to have anaemia than those who did not [odds ratio 5.40 (95% confidence interval: 1.33-22.93)]. Anaemia was detected in eight patients. All patients recovered from anaemia by either beginning or continuing HAART, without requiring blood transfusions. In the HAART era, B19V infection may only be associated with a course of disease characterised by less severe chronic anaemia. This milder course of B19V-associated disease is likely due to the increased immune function of HAART-treated patients.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18824/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALmarilda2_siqueira_etal_IOC_2012.pdfmarilda2_siqueira_etal_IOC_2012.pdfapplication/pdf285530https://www.arca.fiocruz.br/bitstream/icict/18824/2/marilda2_siqueira_etal_IOC_2012.pdfeb6c009cc1fb92fbccea8965d23e9affMD52TEXTmarilda2_siqueira_etal_IOC_2012.pdf.txtmarilda2_siqueira_etal_IOC_2012.pdf.txtExtracted texttext/plain32060https://www.arca.fiocruz.br/bitstream/icict/18824/3/marilda2_siqueira_etal_IOC_2012.pdf.txt6575906b881fd8768d8fa9bcbbf8ffe9MD53icict/188242022-03-23 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| dc.title.pt_BR.fl_str_mv |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| title |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| spellingShingle |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients Azevedo, Kátia Martins Lopes de Parvovirus B19 Humano Anemia Soroconversão Infecção por HIV human parvovirus B19 seroconversion HIV infection anaemia |
| title_short |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| title_full |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| title_fullStr |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| title_full_unstemmed |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| title_sort |
Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients |
| author |
Azevedo, Kátia Martins Lopes de |
| author_facet |
Azevedo, Kátia Martins Lopes de Setúbal, Sérgio Camacho, Luiz Antonio Bastos Garcia, Rita de Cássia Nasser Cubel Siqueira, Marilda Agudo Mendonça Teixeira de Pereira, Renata Freire Alves Oliveira, Solange Artimos de |
| author_role |
author |
| author2 |
Setúbal, Sérgio Camacho, Luiz Antonio Bastos Garcia, Rita de Cássia Nasser Cubel Siqueira, Marilda Agudo Mendonça Teixeira de Pereira, Renata Freire Alves Oliveira, Solange Artimos de |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Azevedo, Kátia Martins Lopes de Setúbal, Sérgio Camacho, Luiz Antonio Bastos Garcia, Rita de Cássia Nasser Cubel Siqueira, Marilda Agudo Mendonça Teixeira de Pereira, Renata Freire Alves Oliveira, Solange Artimos de |
| dc.subject.other.pt_BR.fl_str_mv |
Parvovirus B19 Humano Anemia Soroconversão Infecção por HIV |
| topic |
Parvovirus B19 Humano Anemia Soroconversão Infecção por HIV human parvovirus B19 seroconversion HIV infection anaemia |
| dc.subject.en.pt_BR.fl_str_mv |
human parvovirus B19 seroconversion HIV infection anaemia |
| description |
Universidade Federal Fluminense. Instituto Biomédico. Disciplina de Doenças Infecciosas e Parasitárias. Niterói, RJ, Brasil. |
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2012 |
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2012 |
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2017-05-11T16:05:09Z |
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2017-05-11T16:05:09Z |
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info:eu-repo/semantics/article |
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AZEVEDO, Kátia Martins Lopes de; Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients. Mem Inst Oswaldo Cruz, v.107, n.3, p.356-361, May 2012. |
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https://www.arca.fiocruz.br/handle/icict/18824 |
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0074-0276 |
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1678-8060 |
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AZEVEDO, Kátia Martins Lopes de; Parvovirus B19 seroconversion in a cohort of human immunodeficiency virus-infected patients. Mem Inst Oswaldo Cruz, v.107, n.3, p.356-361, May 2012. 0074-0276 1678-8060 |
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Fundação Oswaldo Cruz. Instituto Oswaldo Cruz |
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Fundação Oswaldo Cruz. Instituto Oswaldo Cruz |
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