Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168 |
Resumo: | Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent. |
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Memórias do Instituto Oswaldo Cruz |
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Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patientsHIVhuman parvovirus B19seroconversionImmunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.Instituto Oswaldo Cruz, Ministério da Saúde2014-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168Memórias do Instituto Oswaldo Cruz v.109 n.2 2014reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760130312info:eu-repo/semantics/openAccessPereira,Renata Freire AlvesGarcia,Rita de Cássia Nasser CubelAzevedo,Kátia Martins Lopes deSetúbal,SérgioSiqueira,Marilda Agudo Mendonça Teixeira deOliveira,Solange Artimos deeng2020-04-25T17:51:41Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:19:28.192Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
spellingShingle |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients Pereira,Renata Freire Alves HIV human parvovirus B19 seroconversion |
title_short |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_full |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_fullStr |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_full_unstemmed |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
title_sort |
Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients |
author |
Pereira,Renata Freire Alves |
author_facet |
Pereira,Renata Freire Alves Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de |
author_role |
author |
author2 |
Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pereira,Renata Freire Alves Garcia,Rita de Cássia Nasser Cubel Azevedo,Kátia Martins Lopes de Setúbal,Sérgio Siqueira,Marilda Agudo Mendonça Teixeira de Oliveira,Solange Artimos de |
dc.subject.por.fl_str_mv |
HIV human parvovirus B19 seroconversion |
topic |
HIV human parvovirus B19 seroconversion |
dc.description.none.fl_txt_mv |
Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent. |
description |
Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0074-02760130312 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.109 n.2 2014 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
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1669937715117817856 |