Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients

Detalhes bibliográficos
Autor(a) principal: Pereira,Renata Freire Alves
Data de Publicação: 2014
Outros Autores: Garcia,Rita de Cássia Nasser Cubel, Azevedo,Kátia Martins Lopes de, Setúbal,Sérgio, Siqueira,Marilda Agudo Mendonça Teixeira de, Oliveira,Solange Artimos de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168
Resumo: Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.
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spelling Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patientsHIVhuman parvovirus B19seroconversionImmunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.Instituto Oswaldo Cruz, Ministério da Saúde2014-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168Memórias do Instituto Oswaldo Cruz v.109 n.2 2014reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760130312info:eu-repo/semantics/openAccessPereira,Renata Freire AlvesGarcia,Rita de Cássia Nasser CubelAzevedo,Kátia Martins Lopes deSetúbal,SérgioSiqueira,Marilda Agudo Mendonça Teixeira deOliveira,Solange Artimos deeng2020-04-25T17:51:41Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:19:28.192Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
title Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
spellingShingle Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
Pereira,Renata Freire Alves
HIV
human parvovirus B19
seroconversion
title_short Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
title_full Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
title_fullStr Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
title_full_unstemmed Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
title_sort Clinical features and laboratory findings of human parvovirus B19 in human immunodeficiency virus-infected patients
author Pereira,Renata Freire Alves
author_facet Pereira,Renata Freire Alves
Garcia,Rita de Cássia Nasser Cubel
Azevedo,Kátia Martins Lopes de
Setúbal,Sérgio
Siqueira,Marilda Agudo Mendonça Teixeira de
Oliveira,Solange Artimos de
author_role author
author2 Garcia,Rita de Cássia Nasser Cubel
Azevedo,Kátia Martins Lopes de
Setúbal,Sérgio
Siqueira,Marilda Agudo Mendonça Teixeira de
Oliveira,Solange Artimos de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira,Renata Freire Alves
Garcia,Rita de Cássia Nasser Cubel
Azevedo,Kátia Martins Lopes de
Setúbal,Sérgio
Siqueira,Marilda Agudo Mendonça Teixeira de
Oliveira,Solange Artimos de
dc.subject.por.fl_str_mv HIV
human parvovirus B19
seroconversion
topic HIV
human parvovirus B19
seroconversion
dc.description.none.fl_txt_mv Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.
description Immunocompromised patients may develop severe chronic anaemia when infected by human parvovirus B19 (B19V). However, this is not the case in human immunodeficiency virus (HIV)-infected patients with good adherence to highly active antiretroviral treatment (HAART). In this study, we investigated the clinical evolution of five HIV-infected patients receiving HAART who had B19V infections confirmed by serum polymerase chain reaction. Four of the patients were infected with genotype 1a strains and the remaining patient was infected with a genotype 3b strain. Anaemia was detected in three of the patients, but all patients recovered without requiring immunoglobulin and/or blood transfusions. In all cases, the attending physicians did not suspect the B19V infections. There was no apparent relationship between the infecting genotype and the clinical course. In the HAART era, B19V infections in HIV-positive patients may be limited, subtle or unapparent.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000200168
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-02760130312
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.109 n.2 2014
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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