Lipid Droplet, a Key Player in Host-Parasite Interactions

Detalhes bibliográficos
Autor(a) principal: Vallochi, Adriana Lima
Data de Publicação: 2018
Outros Autores: Teixeira, Livia, Oliveira, Karina da Silva, Monteiro, Clarissa Menezes Maya, Bozza, Patrícia T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29103
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.
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spelling Vallochi, Adriana LimaTeixeira, LiviaOliveira, Karina da SilvaMonteiro, Clarissa Menezes MayaBozza, Patrícia T.2018-09-27T14:52:58Z2018-09-27T14:52:58Z2018VALLOCHI, Adriana Lima; et al. Lipid Droplet, a Key Player in Host-Parasite interactions. Frontiers in Immunology, v.9, Article 1022, 18p, May 2018.1664-3224https://www.arca.fiocruz.br/handle/icict/2910310.3389/fimmu.2018.01022engFrontiers Mediagotículas lipídicascorpos lipídicosParasitospatógeno intracelulareicosanóidesInflamaçãoresposta imunelipid dropletslipid bodiesparasiteintracellular pathogeneicosanoidsinflammationimmune responseLipid Droplet, a Key Player in Host-Parasite Interactionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.Lipid droplets (lipid bodies, LDs) are dynamic organelles that have important roles in regulating lipid metabolism, energy homeostasis, cell signaling, membrane trafficking, and inflammation. LD biogenesis, composition, and functions are highly regulated and may vary according to the stimuli, cell type, activation state, and inflammatory environment. Increased cytoplasmic LDs are frequently observed in leukocytes and other cells in a number of infectious diseases. Accumulating evidence reveals LDs participation in fundamental mechanisms of host-pathogen interactions, including cell signaling and immunity. LDs are sources of eicosanoid production, and may participate in different aspects of innate signaling and antigen presentation. In addition, intracellular pathogens evolved mechanisms to subvert host metabolism and may use host LDs, as ways of immune evasion and nutrients source. Here, we review mechanisms of LDs biogenesis and their contributions to the infection progress, and discuss the latest discoveries on mechanisms and pathways involving LDs roles as regulators of the immune response to protozoan infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29103/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALkarina_oliveira_etal_IOC_2018.pdfkarina_oliveira_etal_IOC_2018.pdfapplication/pdf992600https://www.arca.fiocruz.br/bitstream/icict/29103/2/karina_oliveira_etal_IOC_2018.pdf656df3012b334725683cafa8471b93aeMD52TEXTkarina_oliveira_etal_IOC_2018.pdf.txtkarina_oliveira_etal_IOC_2018.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Lipid Droplet, a Key Player in Host-Parasite Interactions
title Lipid Droplet, a Key Player in Host-Parasite Interactions
spellingShingle Lipid Droplet, a Key Player in Host-Parasite Interactions
Vallochi, Adriana Lima
gotículas lipídicas
corpos lipídicos
Parasitos
patógeno intracelular
eicosanóides
Inflamação
resposta imune
lipid droplets
lipid bodies
parasite
intracellular pathogen
eicosanoids
inflammation
immune response
title_short Lipid Droplet, a Key Player in Host-Parasite Interactions
title_full Lipid Droplet, a Key Player in Host-Parasite Interactions
title_fullStr Lipid Droplet, a Key Player in Host-Parasite Interactions
title_full_unstemmed Lipid Droplet, a Key Player in Host-Parasite Interactions
title_sort Lipid Droplet, a Key Player in Host-Parasite Interactions
author Vallochi, Adriana Lima
author_facet Vallochi, Adriana Lima
Teixeira, Livia
Oliveira, Karina da Silva
Monteiro, Clarissa Menezes Maya
Bozza, Patrícia T.
author_role author
author2 Teixeira, Livia
Oliveira, Karina da Silva
Monteiro, Clarissa Menezes Maya
Bozza, Patrícia T.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Vallochi, Adriana Lima
Teixeira, Livia
Oliveira, Karina da Silva
Monteiro, Clarissa Menezes Maya
Bozza, Patrícia T.
dc.subject.other.pt_BR.fl_str_mv gotículas lipídicas
corpos lipídicos
Parasitos
patógeno intracelular
eicosanóides
Inflamação
resposta imune
topic gotículas lipídicas
corpos lipídicos
Parasitos
patógeno intracelular
eicosanóides
Inflamação
resposta imune
lipid droplets
lipid bodies
parasite
intracellular pathogen
eicosanoids
inflammation
immune response
dc.subject.en.pt_BR.fl_str_mv lipid droplets
lipid bodies
parasite
intracellular pathogen
eicosanoids
inflammation
immune response
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ. Brasil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-09-27T14:52:58Z
dc.date.available.fl_str_mv 2018-09-27T14:52:58Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VALLOCHI, Adriana Lima; et al. Lipid Droplet, a Key Player in Host-Parasite interactions. Frontiers in Immunology, v.9, Article 1022, 18p, May 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29103
dc.identifier.issn.pt_BR.fl_str_mv 1664-3224
dc.identifier.doi.none.fl_str_mv 10.3389/fimmu.2018.01022
identifier_str_mv VALLOCHI, Adriana Lima; et al. Lipid Droplet, a Key Player in Host-Parasite interactions. Frontiers in Immunology, v.9, Article 1022, 18p, May 2018.
1664-3224
10.3389/fimmu.2018.01022
url https://www.arca.fiocruz.br/handle/icict/29103
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/29103/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/29103/2/karina_oliveira_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/29103/3/karina_oliveira_etal_IOC_2018.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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