Challenges and perspectives in vaccination against leishmaniasis.

Detalhes bibliográficos
Autor(a) principal: Oliveira, Camila Indiani de
Data de Publicação: 2009
Outros Autores: Nascimento, Ivan Pereira, Barral, Aldina Maria Prado, Soto, Manuel, Barral Netto, Manoel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1016/j.parint.2009.07.013
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7401
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
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spelling Oliveira, Camila Indiani deNascimento, Ivan PereiraBarral, Aldina Maria PradoSoto, ManuelBarral Netto, Manoel2014-03-13T13:32:09Z2014-03-13T13:32:09Z2009OLIVEIRA, C. I. de et al. Challenges and perspectives in vaccination against leishmaniasis. Parasitology International, v. 58, p. 319–324, 2009.1873-0329https://www.arca.fiocruz.br/handle/icict/740110.1016/j.parint.2009.07.013engElsevier Ireland Ltd.Challenges and perspectives in vaccination against leishmaniasis.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, BrasilUniversidad Autónoma de Madrid. Facultad de Ciencias. Centro de Biología Molecular Severo Ochoa. Departamento de Biología Molecular. Madrid, SpainFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Instituto de Investigação em Imunologia. Salvador, BA, BrasilThe leishmaniases are a group of diseases caused by protozoa of the genus Leishmania and affect millions of people worldwide. The leishmaniases are transmitted to vertebrate hosts by phlebotomine sand flies. In this review, we focus on several issues that have been poorly addressed in ongoing efforts to develop a vaccine against Leishmania, namely: vaccination with antigens present in sand fly saliva, vaccines based on intracellular Leishmania antigens, and use of recombinant BCG as a vehicle for vaccination. Additionally, we address the differences between L. major and L. braziliensis and the impact that these differences may have on strategies for immunoprophylaxisLeishmaniaSandy flySalivaBCGLeishmania braziliensis/imunologiaLeishmania major/imunologiaLeishmaniose Cutânea/prevenção & controleVacinas ProtozoáriasPsychodidaeSalivaAnimaisAntígenos de Protozoários/genéticaAntígenos de Protozoários/imunologiaAnimaisLeishmaniose Cutânea/parasitologiaCamundongosMycobacterium bovis/genéticaVacinas Protozoárias/administração & dosagemVacinas Protozoárias/imunologiaPsychodidae/imunologiaPsychodidae/parasitologiaSaliva/imunologiaSaliva/parasitologiaVacinaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALOliveira Camila I. Challenges and perspectives....pdfOliveira Camila I. 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dc.title.pt_BR.fl_str_mv Challenges and perspectives in vaccination against leishmaniasis.
title Challenges and perspectives in vaccination against leishmaniasis.
spellingShingle Challenges and perspectives in vaccination against leishmaniasis.
Oliveira, Camila Indiani de
Leishmania
Sandy fly
Saliva
BCG
Leishmania braziliensis/imunologia
Leishmania major/imunologia
Leishmaniose Cutânea/prevenção & controle
Vacinas Protozoárias
Psychodidae
Saliva
Animais
Antígenos de Protozoários/genética
Antígenos de Protozoários/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Camundongos
Mycobacterium bovis/genética
Vacinas Protozoárias/administração & dosagem
Vacinas Protozoárias/imunologia
Psychodidae/imunologia
Psychodidae/parasitologia
Saliva/imunologia
Saliva/parasitologia
Vacinação
title_short Challenges and perspectives in vaccination against leishmaniasis.
title_full Challenges and perspectives in vaccination against leishmaniasis.
title_fullStr Challenges and perspectives in vaccination against leishmaniasis.
title_full_unstemmed Challenges and perspectives in vaccination against leishmaniasis.
title_sort Challenges and perspectives in vaccination against leishmaniasis.
author Oliveira, Camila Indiani de
author_facet Oliveira, Camila Indiani de
Nascimento, Ivan Pereira
Barral, Aldina Maria Prado
Soto, Manuel
Barral Netto, Manoel
author_role author
author2 Nascimento, Ivan Pereira
Barral, Aldina Maria Prado
Soto, Manuel
Barral Netto, Manoel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Camila Indiani de
Nascimento, Ivan Pereira
Barral, Aldina Maria Prado
Soto, Manuel
Barral Netto, Manoel
dc.subject.en.pt_BR.fl_str_mv Leishmania
Sandy fly
Saliva
BCG
topic Leishmania
Sandy fly
Saliva
BCG
Leishmania braziliensis/imunologia
Leishmania major/imunologia
Leishmaniose Cutânea/prevenção & controle
Vacinas Protozoárias
Psychodidae
Saliva
Animais
Antígenos de Protozoários/genética
Antígenos de Protozoários/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Camundongos
Mycobacterium bovis/genética
Vacinas Protozoárias/administração & dosagem
Vacinas Protozoárias/imunologia
Psychodidae/imunologia
Psychodidae/parasitologia
Saliva/imunologia
Saliva/parasitologia
Vacinação
dc.subject.decs.pt_BR.fl_str_mv Leishmania braziliensis/imunologia
Leishmania major/imunologia
Leishmaniose Cutânea/prevenção & controle
Vacinas Protozoárias
Psychodidae
Saliva
Animais
Antígenos de Protozoários/genética
Antígenos de Protozoários/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Camundongos
Mycobacterium bovis/genética
Vacinas Protozoárias/administração & dosagem
Vacinas Protozoárias/imunologia
Psychodidae/imunologia
Psychodidae/parasitologia
Saliva/imunologia
Saliva/parasitologia
Vacinação
description Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2014-03-13T13:32:09Z
dc.date.available.fl_str_mv 2014-03-13T13:32:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, C. I. de et al. Challenges and perspectives in vaccination against leishmaniasis. Parasitology International, v. 58, p. 319–324, 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7401
dc.identifier.issn.none.fl_str_mv 1873-0329
dc.identifier.doi.none.fl_str_mv 10.1016/j.parint.2009.07.013
identifier_str_mv OLIVEIRA, C. I. de et al. Challenges and perspectives in vaccination against leishmaniasis. Parasitology International, v. 58, p. 319–324, 2009.
1873-0329
10.1016/j.parint.2009.07.013
url https://www.arca.fiocruz.br/handle/icict/7401
dc.language.iso.fl_str_mv eng
language eng
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eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ireland Ltd.
publisher.none.fl_str_mv Elsevier Ireland Ltd.
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instname:Fundação Oswaldo Cruz (FIOCRUZ)
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