Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.

Detalhes bibliográficos
Autor(a) principal: Santiago, Helton da Costa
Data de Publicação: 2004
Outros Autores: Oliveira, Carolina Ferreira, Santiago, Luciana, Ferraz, Fernanda Oliveira, Souza, Daniele da Glória de, Freitas, Luiz Antonio Rodrigues de, Afonso, Luís Carlos Crocco, Teixeira, Mauro Martins, Gazzinelli, Ricardo Tostes, Vieira, Leda Quércia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7883
Resumo: Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil
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spelling Santiago, Helton da CostaOliveira, Carolina FerreiraSantiago, LucianaFerraz, Fernanda OliveiraSouza, Daniele da Glória deFreitas, Luiz Antonio Rodrigues deAfonso, Luís Carlos CroccoTeixeira, Mauro MartinsGazzinelli, Ricardo TostesVieira, Leda Quércia2014-07-09T13:15:01Z2014-07-09T13:15:01Z2004SANTIAGO, H. da C. et al. Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major. Infection and Immunity, v. 72, n. 8, p. 4918-4923, 2004.0019-9567https://www.arca.fiocruz.br/handle/icict/788310.1128/IAI.72.8.4918–4923.2004engAmerican Society for MicrobiologyInvolvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal de Ouro Preto. Instituto de Ciências Biológicas e Exatas. Departamento de Ciências Biológicas and Núcleo de Pesquisa em Ciências Biológicas. Ouro Preto, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, BrasilThe expression and putative role of chemokines during infection with Leishmania major in mice were investigated. CCL5 expression correlates with resistance, and blockade of CCL5 rendered mice more susceptible to infection. CCL5 is part of the cascade of events leading to efficient parasite control in L. major infection.Quimiocina CCL5/metabolismoLeishmania majorLeishmaniose Cutânea/imunologiaAnimaisLeishmaniose Cutânea/parasitologiaLeishmaniose Cutânea/fisiopatologiaCamundongosCamundongos Endogâmicos BALB CCamundongos Endogâmicos C57BLinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALSantiago HC Involvement of the....pdfSantiago HC Involvement of the....pdfapplication/pdf1145579https://www.arca.fiocruz.br/bitstream/icict/7883/1/Santiago%20HC%20Involvement%20of%20the....pdf07251cd8fa5dab625dc3337b6e277199MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7883/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTSantiago HC Involvement of the....pdf.txtSantiago HC Involvement of the....pdf.txtExtracted texttext/plain20993https://www.arca.fiocruz.br/bitstream/icict/7883/3/Santiago%20HC%20Involvement%20of%20the....pdf.txt2b633cc872c375009df3142c3ae42668MD53icict/78832023-03-15 14:33:16.46oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:16Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
title Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
spellingShingle Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
Santiago, Helton da Costa
Quimiocina CCL5/metabolismo
Leishmania major
Leishmaniose Cutânea/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Leishmaniose Cutânea/fisiopatologia
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C57BL
title_short Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
title_full Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
title_fullStr Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
title_full_unstemmed Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
title_sort Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major.
author Santiago, Helton da Costa
author_facet Santiago, Helton da Costa
Oliveira, Carolina Ferreira
Santiago, Luciana
Ferraz, Fernanda Oliveira
Souza, Daniele da Glória de
Freitas, Luiz Antonio Rodrigues de
Afonso, Luís Carlos Crocco
Teixeira, Mauro Martins
Gazzinelli, Ricardo Tostes
Vieira, Leda Quércia
author_role author
author2 Oliveira, Carolina Ferreira
Santiago, Luciana
Ferraz, Fernanda Oliveira
Souza, Daniele da Glória de
Freitas, Luiz Antonio Rodrigues de
Afonso, Luís Carlos Crocco
Teixeira, Mauro Martins
Gazzinelli, Ricardo Tostes
Vieira, Leda Quércia
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Santiago, Helton da Costa
Oliveira, Carolina Ferreira
Santiago, Luciana
Ferraz, Fernanda Oliveira
Souza, Daniele da Glória de
Freitas, Luiz Antonio Rodrigues de
Afonso, Luís Carlos Crocco
Teixeira, Mauro Martins
Gazzinelli, Ricardo Tostes
Vieira, Leda Quércia
dc.subject.decs.pt_BR.fl_str_mv Quimiocina CCL5/metabolismo
Leishmania major
Leishmaniose Cutânea/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Leishmaniose Cutânea/fisiopatologia
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C57BL
topic Quimiocina CCL5/metabolismo
Leishmania major
Leishmaniose Cutânea/imunologia
Animais
Leishmaniose Cutânea/parasitologia
Leishmaniose Cutânea/fisiopatologia
Camundongos
Camundongos Endogâmicos BALB C
Camundongos Endogâmicos C57BL
description Universidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Instituto de Ciências Biológicas. Belo Horizonte, MG, Brasil
publishDate 2004
dc.date.issued.fl_str_mv 2004
dc.date.accessioned.fl_str_mv 2014-07-09T13:15:01Z
dc.date.available.fl_str_mv 2014-07-09T13:15:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SANTIAGO, H. da C. et al. Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major. Infection and Immunity, v. 72, n. 8, p. 4918-4923, 2004.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7883
dc.identifier.issn.none.fl_str_mv 0019-9567
dc.identifier.doi.none.fl_str_mv 10.1128/IAI.72.8.4918–4923.2004
identifier_str_mv SANTIAGO, H. da C. et al. Involvement of the chemokine RANTES (CCL5) in resistance to experimental infection with Leishmania major. Infection and Immunity, v. 72, n. 8, p. 4918-4923, 2004.
0019-9567
10.1128/IAI.72.8.4918–4923.2004
url https://www.arca.fiocruz.br/handle/icict/7883
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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