Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
Autor(a) principal: | |
---|---|
Data de Publicação: | 2010 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/7387 |
Resumo: | Universidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil |
id |
CRUZ_c51fdc79728da2965929f78f66443234 |
---|---|
oai_identifier_str |
oai:www.arca.fiocruz.br:icict/7387 |
network_acronym_str |
CRUZ |
network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
repository_id_str |
2135 |
spelling |
Aquino, Dorlene Maria Cardoso deCaldas, Arlene de Jesus MendesMiranda, José CarlosSilva, Antonio Augusto Moura daBarral Netto, ManoelBarral, Aldina Maria Prado2014-03-10T17:04:07Z2014-03-10T17:04:07Z2010AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010.1476-1645https://www.arca.fiocruz.br/handle/icict/738710.4269/ajtmh.2010.10-0182engThe American Society of Tropical Medicine and HygieneEpidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigeninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Maranhão. Departamento de Saúde Pública. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Imuno-regulação. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia iii - INCT. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Imunoparasitologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia iii - INCT. Salvador, BA, BrasilRecent reports from animal models and from cross-sectional studies have suggested that host responses to anti-Lutzomyia longipalpis saliva antibodies may be related to delayed-type hypersensitivity to Leishmania antigen. In a prospective cohort study, we evaluated 1,080 children from two endemic areas for visceral leishmaniasis (VL) by means of Kaplan-Meier analysis. The incidence rate of delayed-type hypersensitivity to Leishmania antigen, measured at the 24th follow-up month, was higher among those reactive to Lu. longipalpis saliva antibodies at the beginning of the study (0.0217 cases per person-month) than among those previously negative (0.0131 cases per person-month) (P value for the log-rank test = 0.0006). It seems that mounting an anti-saliva immune response helps the development of a cell-mediated anti-Leishmania response.Anticorpos/sangueAntígenos de Protozoários/imunologiaHipersensibilidade Tardia/etiologiaLeishmania/imunologiaLeishmaniose Visceral/diagnósticoPsychodidae/imunologiaAnimaisCriançaPré-EscolarEstudos de CoortesHumanosHipersensibilidade Tardia/imunologiaLactenteLeishmaniose Visceral/imunologiaRecém-Nascidoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALAquino D M C Epidemiological Study....pdfAquino D M C Epidemiological Study....pdfapplication/pdf557538https://www.arca.fiocruz.br/bitstream/icict/7387/1/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf95382594fd4746a392752483557e5fdbMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7387/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTAquino D M C Epidemiological Study....pdf.txtAquino D M C Epidemiological Study....pdf.txtExtracted texttext/plain17893https://www.arca.fiocruz.br/bitstream/icict/7387/5/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.txt04956102f059d7846da9fd7cfb15e724MD55THUMBNAILAquino D M C Epidemiological Study....pdf.jpgAquino D M C Epidemiological Study....pdf.jpgGenerated Thumbnailimage/jpeg2345https://www.arca.fiocruz.br/bitstream/icict/7387/4/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.jpgbe392372f7587ae7274c201d5988abbdMD54icict/73872023-03-15 14:33:26.611oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:26Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
title |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
spellingShingle |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen Aquino, Dorlene Maria Cardoso de Anticorpos/sangue Antígenos de Protozoários/imunologia Hipersensibilidade Tardia/etiologia Leishmania/imunologia Leishmaniose Visceral/diagnóstico Psychodidae/imunologia Animais Criança Pré-Escolar Estudos de Coortes Humanos Hipersensibilidade Tardia/imunologia Lactente Leishmaniose Visceral/imunologia Recém-Nascido |
title_short |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
title_full |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
title_fullStr |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
title_full_unstemmed |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
title_sort |
Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen |
author |
Aquino, Dorlene Maria Cardoso de |
author_facet |
Aquino, Dorlene Maria Cardoso de Caldas, Arlene de Jesus Mendes Miranda, José Carlos Silva, Antonio Augusto Moura da Barral Netto, Manoel Barral, Aldina Maria Prado |
author_role |
author |
author2 |
Caldas, Arlene de Jesus Mendes Miranda, José Carlos Silva, Antonio Augusto Moura da Barral Netto, Manoel Barral, Aldina Maria Prado |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Aquino, Dorlene Maria Cardoso de Caldas, Arlene de Jesus Mendes Miranda, José Carlos Silva, Antonio Augusto Moura da Barral Netto, Manoel Barral, Aldina Maria Prado |
dc.subject.decs.pt_BR.fl_str_mv |
Anticorpos/sangue Antígenos de Protozoários/imunologia Hipersensibilidade Tardia/etiologia Leishmania/imunologia Leishmaniose Visceral/diagnóstico Psychodidae/imunologia Animais Criança Pré-Escolar Estudos de Coortes Humanos Hipersensibilidade Tardia/imunologia Lactente Leishmaniose Visceral/imunologia Recém-Nascido |
topic |
Anticorpos/sangue Antígenos de Protozoários/imunologia Hipersensibilidade Tardia/etiologia Leishmania/imunologia Leishmaniose Visceral/diagnóstico Psychodidae/imunologia Animais Criança Pré-Escolar Estudos de Coortes Humanos Hipersensibilidade Tardia/imunologia Lactente Leishmaniose Visceral/imunologia Recém-Nascido |
description |
Universidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2014-03-10T17:04:07Z |
dc.date.available.fl_str_mv |
2014-03-10T17:04:07Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/7387 |
dc.identifier.issn.none.fl_str_mv |
1476-1645 |
dc.identifier.doi.none.fl_str_mv |
10.4269/ajtmh.2010.10-0182 |
identifier_str_mv |
AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010. 1476-1645 10.4269/ajtmh.2010.10-0182 |
url |
https://www.arca.fiocruz.br/handle/icict/7387 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
The American Society of Tropical Medicine and Hygiene |
publisher.none.fl_str_mv |
The American Society of Tropical Medicine and Hygiene |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/7387/1/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf https://www.arca.fiocruz.br/bitstream/icict/7387/2/license.txt https://www.arca.fiocruz.br/bitstream/icict/7387/5/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.txt https://www.arca.fiocruz.br/bitstream/icict/7387/4/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.jpg |
bitstream.checksum.fl_str_mv |
95382594fd4746a392752483557e5fdb 7d48279ffeed55da8dfe2f8e81f3b81f 04956102f059d7846da9fd7cfb15e724 be392372f7587ae7274c201d5988abbd |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
_version_ |
1798324731230814208 |