Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation

Detalhes bibliográficos
Autor(a) principal: Suffys, Philip Noel
Data de Publicação: 2018
Outros Autores: Múltipla autoria - ver em Notas
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31360
Resumo: AUTHORS - Ola B. Brynildsrud1, Caitlin S. Pepperell2,3, Philip Suffys4, Louis Grandjean5, Johana Monteserin6,7, Nadia Debech1, Jon Bohlin1, Kristian Alfsnes1, John O.-H. Pettersson1,8,9,10, Ingerid Kirkeleite1, Fatima Fandinho11, Marcia Aparecida da Silva11, Joao Perdigao12, Isabel Portugal12, Miguel Viveiros13, Taane Clark14,15, Maxine Caws16,17, Sarah Dunstan18, Phan Vuong Khac Thai19, Beatriz Lopez6, Viviana Ritacco6,7, Andrew Kitchen20, Tyler S. Brown21, Dick van Soolingen22, Mary B. O’Neill3,23*, Kathryn E. Holt14,24, Edward J. Feil25, Barun Mathema26, Francois Balloux27, Vegard Eldholm1† - AFFILIATIONS - 1Division of Infectious Diseases and Environmental Health, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway. 2Division of Infectious Disease, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 3Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 4Laboratory of Molecular Biology Applied to Mycobacteria, Oswaldo Cruz Institute, Avenida Brasil 4365, C.P. 926, Manguinhos 21040-360, Rio de Janeiro, Brazil. 5Department of Paediatric Infectious Diseases, Imperial College London, W2 1NY, London, UK. 6Instituto Nacional de Enfermedades Infecciosas, ANLIS Carlos Malbran, Buenos Aires, Argentina. 7Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires, Argentina. 8Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden. 9Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, New South Wales 2006, Australia. 10Public Health Agency of Sweden, Nobels vg 18, SE-171 82 Solna, Sweden. 11Laboratorio de Bacteriologia da Tuberculose, Centro de Referłncia Professor Helio Fraga-Jacarepagu, Estrada de Curicica 2000, Brazil. 12Instituto de Investigao do Medicamento, Faculdade de Farmcia, Universidade de Lisboa, Lisboa, Portugal. 13Unidade de Microbiologia Medica, Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal. 14Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 15Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 16Liverpool School of Tropical medicine, Department of Clinical Sciences, Liverpool, UK. 17Birat-Nepal Medical Trust, Lazimpat, Kathmandu, Nepal. 18Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. 19Pham Ngoc Thach Hospital for TB and Lung Diseases, Ho Chi Minh City, Vietnam. 20Department of Anthropology, University of Iowa, Iowa City, IA 52242, USA. 21Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA. 22Center for Infectious Disease Research, Diagnostics and Perinatal Screening, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, Netherlands. 23Laboratory of Genetics, University of Wisconsin- Madison, Madison, WI 53706, USA. 24Department of Biochemistry and Molecular Biology and Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia. 25Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK. 26Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA. 27UCL Genetics Institute, University College London, London WC1E 6BT, UK.
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spelling Suffys, Philip NoelMúltipla autoria - ver em Notas2019-01-31T15:19:23Z2019-01-31T15:19:23Z2018BRYNILDSRUD, Ola. B. et al. Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation. Sci. Adv., n.4, eaat5869, 11p, Oct. 2018.https://www.arca.fiocruz.br/handle/icict/3136010.1126/sciadv.aat58692375-2548AUTHORS - Ola B. Brynildsrud1, Caitlin S. Pepperell2,3, Philip Suffys4, Louis Grandjean5, Johana Monteserin6,7, Nadia Debech1, Jon Bohlin1, Kristian Alfsnes1, John O.-H. Pettersson1,8,9,10, Ingerid Kirkeleite1, Fatima Fandinho11, Marcia Aparecida da Silva11, Joao Perdigao12, Isabel Portugal12, Miguel Viveiros13, Taane Clark14,15, Maxine Caws16,17, Sarah Dunstan18, Phan Vuong Khac Thai19, Beatriz Lopez6, Viviana Ritacco6,7, Andrew Kitchen20, Tyler S. Brown21, Dick van Soolingen22, Mary B. O’Neill3,23*, Kathryn E. Holt14,24, Edward J. Feil25, Barun Mathema26, Francois Balloux27, Vegard Eldholm1† - AFFILIATIONS - 1Division of Infectious Diseases and Environmental Health, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway. 2Division of Infectious Disease, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 3Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 4Laboratory of Molecular Biology Applied to Mycobacteria, Oswaldo Cruz Institute, Avenida Brasil 4365, C.P. 926, Manguinhos 21040-360, Rio de Janeiro, Brazil. 5Department of Paediatric Infectious Diseases, Imperial College London, W2 1NY, London, UK. 6Instituto Nacional de Enfermedades Infecciosas, ANLIS Carlos Malbran, Buenos Aires, Argentina. 7Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires, Argentina. 8Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden. 9Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, New South Wales 2006, Australia. 10Public Health Agency of Sweden, Nobels vg 18, SE-171 82 Solna, Sweden. 11Laboratorio de Bacteriologia da Tuberculose, Centro de Referłncia Professor Helio Fraga-Jacarepagu, Estrada de Curicica 2000, Brazil. 12Instituto de Investigao do Medicamento, Faculdade de Farmcia, Universidade de Lisboa, Lisboa, Portugal. 13Unidade de Microbiologia Medica, Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal. 14Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 15Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 16Liverpool School of Tropical medicine, Department of Clinical Sciences, Liverpool, UK. 17Birat-Nepal Medical Trust, Lazimpat, Kathmandu, Nepal. 18Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. 19Pham Ngoc Thach Hospital for TB and Lung Diseases, Ho Chi Minh City, Vietnam. 20Department of Anthropology, University of Iowa, Iowa City, IA 52242, USA. 21Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA. 22Center for Infectious Disease Research, Diagnostics and Perinatal Screening, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, Netherlands. 23Laboratory of Genetics, University of Wisconsin- Madison, Madison, WI 53706, USA. 24Department of Biochemistry and Molecular Biology and Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia. 25Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK. 26Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA. 27UCL Genetics Institute, University College London, London WC1E 6BT, UK.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular Aplicada em Micobactérias. Rio de Janeiro, RJ. Brasil.Múltipla autoria - ver em NotasOn the basis of population genomic and phylogeographic analyses of 1669 Mycobacterium tuberculosis lineage 4 (L4) genomes, we find that dispersal of L4 has been completely dominated by historical migrations out of Europe. We demonstrate an intimate temporal relationship between European colonial expansion into Africa and the Americas and the spread of L4 tuberculosis (TB). Markedly, in the age of antibiotics, mutations conferring antimicrobial resistance overwhelmingly emerged locally (at the level of nations), with minimal cross-border transmission of resistance. The latter finding was found to reflect the relatively recent emergence of these mutations, as a similar degree of local restriction was observed for susceptible variants emerging on comparable time scales. The restricted international transmission of drug-resistant TB suggests that containment efforts at the level of individual countries could be successful.engAmerican Association for Advancement of ScienceMycobacterium tuberculosisLinhagem 4Migração colonialAdaptação localMycobacterium tuberculosisLineage 4Colonial migrationLocal adaptationGlobal expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
title Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
spellingShingle Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
Suffys, Philip Noel
Mycobacterium tuberculosis
Linhagem 4
Migração colonial
Adaptação local
Mycobacterium tuberculosis
Lineage 4
Colonial migration
Local adaptation
title_short Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
title_full Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
title_fullStr Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
title_full_unstemmed Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
title_sort Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation
author Suffys, Philip Noel
author_facet Suffys, Philip Noel
Múltipla autoria - ver em Notas
author_role author
author2 Múltipla autoria - ver em Notas
author2_role author
dc.contributor.author.fl_str_mv Suffys, Philip Noel
Múltipla autoria - ver em Notas
dc.subject.other.pt_BR.fl_str_mv Mycobacterium tuberculosis
Linhagem 4
Migração colonial
Adaptação local
topic Mycobacterium tuberculosis
Linhagem 4
Migração colonial
Adaptação local
Mycobacterium tuberculosis
Lineage 4
Colonial migration
Local adaptation
dc.subject.en.pt_BR.fl_str_mv Mycobacterium tuberculosis
Lineage 4
Colonial migration
Local adaptation
description AUTHORS - Ola B. Brynildsrud1, Caitlin S. Pepperell2,3, Philip Suffys4, Louis Grandjean5, Johana Monteserin6,7, Nadia Debech1, Jon Bohlin1, Kristian Alfsnes1, John O.-H. Pettersson1,8,9,10, Ingerid Kirkeleite1, Fatima Fandinho11, Marcia Aparecida da Silva11, Joao Perdigao12, Isabel Portugal12, Miguel Viveiros13, Taane Clark14,15, Maxine Caws16,17, Sarah Dunstan18, Phan Vuong Khac Thai19, Beatriz Lopez6, Viviana Ritacco6,7, Andrew Kitchen20, Tyler S. Brown21, Dick van Soolingen22, Mary B. O’Neill3,23*, Kathryn E. Holt14,24, Edward J. Feil25, Barun Mathema26, Francois Balloux27, Vegard Eldholm1† - AFFILIATIONS - 1Division of Infectious Diseases and Environmental Health, Norwegian Institute of Public Health, Lovisenberggata 8, 0456 Oslo, Norway. 2Division of Infectious Disease, Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 3Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53726, USA. 4Laboratory of Molecular Biology Applied to Mycobacteria, Oswaldo Cruz Institute, Avenida Brasil 4365, C.P. 926, Manguinhos 21040-360, Rio de Janeiro, Brazil. 5Department of Paediatric Infectious Diseases, Imperial College London, W2 1NY, London, UK. 6Instituto Nacional de Enfermedades Infecciosas, ANLIS Carlos Malbran, Buenos Aires, Argentina. 7Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Buenos Aires, Argentina. 8Department of Medical Biochemistry and Microbiology, Zoonosis Science Center, Uppsala University, Uppsala, Sweden. 9Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, New South Wales 2006, Australia. 10Public Health Agency of Sweden, Nobels vg 18, SE-171 82 Solna, Sweden. 11Laboratorio de Bacteriologia da Tuberculose, Centro de Referłncia Professor Helio Fraga-Jacarepagu, Estrada de Curicica 2000, Brazil. 12Instituto de Investigao do Medicamento, Faculdade de Farmcia, Universidade de Lisboa, Lisboa, Portugal. 13Unidade de Microbiologia Medica, Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal. 14Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 15Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK. 16Liverpool School of Tropical medicine, Department of Clinical Sciences, Liverpool, UK. 17Birat-Nepal Medical Trust, Lazimpat, Kathmandu, Nepal. 18Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. 19Pham Ngoc Thach Hospital for TB and Lung Diseases, Ho Chi Minh City, Vietnam. 20Department of Anthropology, University of Iowa, Iowa City, IA 52242, USA. 21Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA. 22Center for Infectious Disease Research, Diagnostics and Perinatal Screening, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, Netherlands. 23Laboratory of Genetics, University of Wisconsin- Madison, Madison, WI 53706, USA. 24Department of Biochemistry and Molecular Biology and Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia. 25Milner Centre for Evolution, Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK. 26Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA. 27UCL Genetics Institute, University College London, London WC1E 6BT, UK.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-01-31T15:19:23Z
dc.date.available.fl_str_mv 2019-01-31T15:19:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BRYNILDSRUD, Ola. B. et al. Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation. Sci. Adv., n.4, eaat5869, 11p, Oct. 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31360
dc.identifier.doi.none.fl_str_mv 10.1126/sciadv.aat5869
dc.identifier.eissn.none.fl_str_mv 2375-2548
identifier_str_mv BRYNILDSRUD, Ola. B. et al. Global expansion of Mycobacterium tuberculosis lineage 4 shaped by colonial migration and local adaptation. Sci. Adv., n.4, eaat5869, 11p, Oct. 2018.
10.1126/sciadv.aat5869
2375-2548
url https://www.arca.fiocruz.br/handle/icict/31360
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Association for Advancement of Science
publisher.none.fl_str_mv American Association for Advancement of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31360/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/31360/2/philip_suffys_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/31360/3/philip_suffys_etal_IOC_2018.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
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acceb02957a4d64782d41e86c0ea1e26
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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