The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil

Detalhes bibliográficos
Autor(a) principal: Silva, Thais Lemos
Data de Publicação: 2021
Outros Autores: Telleria, Erich Loza, Traub-Csekö, Yara Maria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/46371
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitas e Vetores. Rio de Janeiro, RJ, Brasil.
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spelling Silva, Thais LemosTelleria, Erich LozaTraub-Csekö, Yara Maria2021-03-16T19:23:14Z2021-03-16T19:23:14Z2021SILVA, Thais Lemos; TELERIA, Erich Loza; TRAUB-CSEKO¨, Yara Maria. The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 116, e200571, 7p, 2021.0074-0276https://www.arca.fiocruz.br/handle/icict/4637110.1590/0074-027602005711678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Ambiente intestinal de mosca areiaAdaptação de parasitas ao vetorInteração de moscas de leishmania-areiaLeishmania-sand fly interactionParasite adaptation to vectorSand fly gut environmentThe gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitas e Vetores. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitas e Vetores. Rio de Janeiro, RJ, Brasil / Charles University, Faculty of Science, Department of Parasitology. Prague, Czech Republic.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitas e Vetores. Rio de Janeiro, RJ, Brasil.Leishmania infantum chagasi is the causative agent and Lutzomyia longipalpis is the main vector of visceral leishmaniasis in the Americas. We investigated the expression of Leishmania genes within L. longipalpis after artificial infection. mRNAs from genes involved in sugar and amino acid metabolism were upregulated at times of high parasite proliferation inside the insect. mRNAs from genes involved in metacyclogenesis had higher expression in late stages of infection. Other modulated genes of interest were involved in immunomodulation, purine salvage pathway and protein recycling. These data reveal aspects of the adaptation of the parasite to the microenvironment of the vector gut and reflect the preparation for infection in the vertebrate.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/46371/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALThaisSilva_YaraCseko_etal_IOC_2021.pdfThaisSilva_YaraCseko_etal_IOC_2021.pdfapplication/pdf601983https://www.arca.fiocruz.br/bitstream/icict/46371/2/ThaisSilva_YaraCseko_etal_IOC_2021.pdf530fbb6395a889c6f04374353c6903edMD52TEXTThaisSilva_YaraCseko_etal_IOC_2021.pdf.txtThaisSilva_YaraCseko_etal_IOC_2021.pdf.txtExtracted texttext/plain31122https://www.arca.fiocruz.br/bitstream/icict/46371/3/ThaisSilva_YaraCseko_etal_IOC_2021.pdf.txtc34c1508d132e93fb5b07b47bd6285ccMD53icict/463712021-03-17 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dc.title.pt_BR.fl_str_mv The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
title The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
spellingShingle The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
Silva, Thais Lemos
Ambiente intestinal de mosca areia
Adaptação de parasitas ao vetor
Interação de moscas de leishmania-areia
Leishmania-sand fly interaction
Parasite adaptation to vector
Sand fly gut environment
title_short The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
title_full The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
title_fullStr The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
title_full_unstemmed The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
title_sort The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil
author Silva, Thais Lemos
author_facet Silva, Thais Lemos
Telleria, Erich Loza
Traub-Csekö, Yara Maria
author_role author
author2 Telleria, Erich Loza
Traub-Csekö, Yara Maria
author2_role author
author
dc.contributor.author.fl_str_mv Silva, Thais Lemos
Telleria, Erich Loza
Traub-Csekö, Yara Maria
dc.subject.other.pt_BR.fl_str_mv Ambiente intestinal de mosca areia
Adaptação de parasitas ao vetor
Interação de moscas de leishmania-areia
topic Ambiente intestinal de mosca areia
Adaptação de parasitas ao vetor
Interação de moscas de leishmania-areia
Leishmania-sand fly interaction
Parasite adaptation to vector
Sand fly gut environment
dc.subject.en.pt_BR.fl_str_mv Leishmania-sand fly interaction
Parasite adaptation to vector
Sand fly gut environment
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitas e Vetores. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-03-16T19:23:14Z
dc.date.available.fl_str_mv 2021-03-16T19:23:14Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Thais Lemos; TELERIA, Erich Loza; TRAUB-CSEKO¨, Yara Maria. The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 116, e200571, 7p, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/46371
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/0074-02760200571
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv SILVA, Thais Lemos; TELERIA, Erich Loza; TRAUB-CSEKO¨, Yara Maria. The gene expression of Leishmania infantum chagasi inside Lutzomyia longipalpis, the main vector of visceral leishmaniasis in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 116, e200571, 7p, 2021.
0074-0276
10.1590/0074-02760200571
1678-8060
url https://www.arca.fiocruz.br/handle/icict/46371
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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