Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação

Detalhes bibliográficos
Autor(a) principal: Medeiros,Sebastião Freitas de
Data de Publicação: 2021
Outros Autores: Barbosa,Bruna Barcelo, Medeiros,Matheus Antonio Souto de, Yamamoto,Márcia Marly Winck
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista brasileira de ginecologia e obstetrícia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000600480
Resumo: Abstract The process of ovulation involves multiple and iterrelated genetic, biochemical, and morphological events: cessation of the proliferation of granulosa cells, resumption of oocyte meiosis, expansion of cumulus cell-oocyte complexes, digestion of the follicle wall, and extrusion of the metaphase-II oocyte. The present narrative review examines these interrelated steps in detail. The combined or isolated roles of the folliclestimulating hormone (FSH) and luteinizing hormone (LH) are highlighted. Genes indiced by the FSH genes are relevant in the cumulus expansion, and LH-induced genes are critical for the resumption ofmeiosis and digestion of the follicle wall. A nonhuman model for follicle-wall digestion and oocyte release was provided.
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spelling Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulaçãogranulosa cellsfollicle-stimulating hormoneluteinizing hormoneoocytesovarian follicleAbstract The process of ovulation involves multiple and iterrelated genetic, biochemical, and morphological events: cessation of the proliferation of granulosa cells, resumption of oocyte meiosis, expansion of cumulus cell-oocyte complexes, digestion of the follicle wall, and extrusion of the metaphase-II oocyte. The present narrative review examines these interrelated steps in detail. The combined or isolated roles of the folliclestimulating hormone (FSH) and luteinizing hormone (LH) are highlighted. Genes indiced by the FSH genes are relevant in the cumulus expansion, and LH-induced genes are critical for the resumption ofmeiosis and digestion of the follicle wall. A nonhuman model for follicle-wall digestion and oocyte release was provided.Federação Brasileira das Sociedades de Ginecologia e Obstetrícia2021-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000600480Revista Brasileira de Ginecologia e Obstetrícia v.43 n.6 2021reponame:Revista brasileira de ginecologia e obstetrícia (Online)instname:Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)instacron:FEBRASGO10.1055/s-0041-1731379info:eu-repo/semantics/openAccessMedeiros,Sebastião Freitas deBarbosa,Bruna BarceloMedeiros,Matheus Antonio Souto deYamamoto,Márcia Marly Winckeng2021-09-03T00:00:00Zoai:scielo:S0100-72032021000600480Revistahttp://www.scielo.br/rbgohttps://old.scielo.br/oai/scielo-oai.phppublicações@febrasgo.org.br||rbgo@fmrp.usp.br1806-93390100-7203opendoar:2021-09-03T00:00Revista brasileira de ginecologia e obstetrícia (Online) - Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)false
dc.title.none.fl_str_mv Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
title Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
spellingShingle Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
Medeiros,Sebastião Freitas de
granulosa cells
follicle-stimulating hormone
luteinizing hormone
oocytes
ovarian follicle
title_short Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
title_full Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
title_fullStr Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
title_full_unstemmed Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
title_sort Morphology and Biochemistry of Ovulation Morfologia e bioquímica da ovulação
author Medeiros,Sebastião Freitas de
author_facet Medeiros,Sebastião Freitas de
Barbosa,Bruna Barcelo
Medeiros,Matheus Antonio Souto de
Yamamoto,Márcia Marly Winck
author_role author
author2 Barbosa,Bruna Barcelo
Medeiros,Matheus Antonio Souto de
Yamamoto,Márcia Marly Winck
author2_role author
author
author
dc.contributor.author.fl_str_mv Medeiros,Sebastião Freitas de
Barbosa,Bruna Barcelo
Medeiros,Matheus Antonio Souto de
Yamamoto,Márcia Marly Winck
dc.subject.por.fl_str_mv granulosa cells
follicle-stimulating hormone
luteinizing hormone
oocytes
ovarian follicle
topic granulosa cells
follicle-stimulating hormone
luteinizing hormone
oocytes
ovarian follicle
description Abstract The process of ovulation involves multiple and iterrelated genetic, biochemical, and morphological events: cessation of the proliferation of granulosa cells, resumption of oocyte meiosis, expansion of cumulus cell-oocyte complexes, digestion of the follicle wall, and extrusion of the metaphase-II oocyte. The present narrative review examines these interrelated steps in detail. The combined or isolated roles of the folliclestimulating hormone (FSH) and luteinizing hormone (LH) are highlighted. Genes indiced by the FSH genes are relevant in the cumulus expansion, and LH-induced genes are critical for the resumption ofmeiosis and digestion of the follicle wall. A nonhuman model for follicle-wall digestion and oocyte release was provided.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000600480
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032021000600480
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1055/s-0041-1731379
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
dc.source.none.fl_str_mv Revista Brasileira de Ginecologia e Obstetrícia v.43 n.6 2021
reponame:Revista brasileira de ginecologia e obstetrícia (Online)
instname:Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
instacron:FEBRASGO
instname_str Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
instacron_str FEBRASGO
institution FEBRASGO
reponame_str Revista brasileira de ginecologia e obstetrícia (Online)
collection Revista brasileira de ginecologia e obstetrícia (Online)
repository.name.fl_str_mv Revista brasileira de ginecologia e obstetrícia (Online) - Federação Brasileira das Sociedades de Ginecologia e Obstetrícia (FEBRASGO)
repository.mail.fl_str_mv publicações@febrasgo.org.br||rbgo@fmrp.usp.br
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