Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Fitos |
Texto Completo: | https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384 |
Resumo: | Cancer pain is a current problem of high prevalence and difficult to manage. Searching for new perspectives for the relief of pain levels in cancer patients, the use of cannabis appears as a therapeutic alternative. The objective was to highlight, through scientific evidence, the pharmacological potential of the Cannabis sativa L. (cannabaceae) plant on cancer pain treatment. A literature review was carried out using the following databases: SciELO, LILACS, Science Direct and PubMed, considering works published between 2007 and 2020. After applying the inclusion and exclusion criteria, 25 articles were selected. The results indicated that the Cannabis sativa pharmacological potential is linked to the large number of chemical substances present in its composition, the main class being called cannabinoids. Such compounds have numerous biological properties, such as antiemetic, neuroprotective, anti-inflammatory and anticancer activities, and may be beneficial on cancer pain treatment and psychological disorders. Currently, there is a drug in clinical use derived from cannabinoids being used to relieve cancer pain, but it is limited to Canada. It appears that perception of pain denotes a multidimensional phenomenon, which in cancer patients presents itself in a disabling way, with Cannabis sativa being a therapeutic possibility for the relief of pain levels. |
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Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological painCannabis sativa L. (cannabaceae): alternativa para o tratamento da dor oncológicaCannabis sativaPainCancer patientCancerCannabis sativaDorPaciente oncológicoCâncerCancer pain is a current problem of high prevalence and difficult to manage. Searching for new perspectives for the relief of pain levels in cancer patients, the use of cannabis appears as a therapeutic alternative. The objective was to highlight, through scientific evidence, the pharmacological potential of the Cannabis sativa L. (cannabaceae) plant on cancer pain treatment. A literature review was carried out using the following databases: SciELO, LILACS, Science Direct and PubMed, considering works published between 2007 and 2020. After applying the inclusion and exclusion criteria, 25 articles were selected. The results indicated that the Cannabis sativa pharmacological potential is linked to the large number of chemical substances present in its composition, the main class being called cannabinoids. Such compounds have numerous biological properties, such as antiemetic, neuroprotective, anti-inflammatory and anticancer activities, and may be beneficial on cancer pain treatment and psychological disorders. Currently, there is a drug in clinical use derived from cannabinoids being used to relieve cancer pain, but it is limited to Canada. It appears that perception of pain denotes a multidimensional phenomenon, which in cancer patients presents itself in a disabling way, with Cannabis sativa being a therapeutic possibility for the relief of pain levels.A dor oncológica configura-se como uma problemática atual de alta prevalência e difícil manejo. Logo, na busca por novas perspectivas para o alívio dos níveis álgicos de pacientes oncológicos, o uso da Cannabis surge como uma alternativa terapêutica. Diante disso, objetivou-se destacar, neste estudo, o potencial farmacológico da planta Cannabis sativa L. (cannabaceae) no tratamento da dor oncológica. Assim, realizou-se uma revisão da literatura através das bases de dados: SciELO, LILACS, Science direct e PubMed, considerando trabalhos publicados entre 2007 e 2020. Após a aplicação dos critérios de inclusão e exclusão, 25 artigos foram selecionados. Observa-se que a potencialidade farmacológica da Cannabis sativa está ligada ao grande número de substâncias químicas presentes em sua composição, sendo a principal classe denominada canabinoides. Tais compostos possuem inúmeras propriedades biológicas, como atividade antiemética, neuroprotetora, anti-inflamatória e anticâncer, podendo ser benéfica no tratamento da dor oncológica e distúrbios psíquicos. Atualmente, há um medicamento em uso clínico derivado dos canabinoides, sendo utilizado para aliviar algias oncológicas, porém encontra-se limitado ao Canadá.Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2023-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmltext/xmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/138410.32712/2446-4775.2022.1384Revista Fitos; Vol. 17 No. 1 (2023); 119-127Revista Fitos; Vol. 17 Núm. 1 (2023); 119-127Revista Fitos; v. 17 n. 1 (2023); 119-1272446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1290https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1291https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1377Copyright (c) 2022 Revista Fitoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Viviane Gomes daSilva, Kelvyn Kennedy de FigueiredoDantas, Bruna Braga2023-04-18T13:28:16Zoai:ojs.revistafitos.far.fiocruz.br:article/1384Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2023-04-18T13:28:16Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain Cannabis sativa L. (cannabaceae): alternativa para o tratamento da dor oncológica |
title |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
spellingShingle |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain Silva, Viviane Gomes da Cannabis sativa Pain Cancer patient Cancer Cannabis sativa Dor Paciente oncológico Câncer |
title_short |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
title_full |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
title_fullStr |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
title_full_unstemmed |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
title_sort |
Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain |
author |
Silva, Viviane Gomes da |
author_facet |
Silva, Viviane Gomes da Silva, Kelvyn Kennedy de Figueiredo Dantas, Bruna Braga |
author_role |
author |
author2 |
Silva, Kelvyn Kennedy de Figueiredo Dantas, Bruna Braga |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Silva, Viviane Gomes da Silva, Kelvyn Kennedy de Figueiredo Dantas, Bruna Braga |
dc.subject.por.fl_str_mv |
Cannabis sativa Pain Cancer patient Cancer Cannabis sativa Dor Paciente oncológico Câncer |
topic |
Cannabis sativa Pain Cancer patient Cancer Cannabis sativa Dor Paciente oncológico Câncer |
description |
Cancer pain is a current problem of high prevalence and difficult to manage. Searching for new perspectives for the relief of pain levels in cancer patients, the use of cannabis appears as a therapeutic alternative. The objective was to highlight, through scientific evidence, the pharmacological potential of the Cannabis sativa L. (cannabaceae) plant on cancer pain treatment. A literature review was carried out using the following databases: SciELO, LILACS, Science Direct and PubMed, considering works published between 2007 and 2020. After applying the inclusion and exclusion criteria, 25 articles were selected. The results indicated that the Cannabis sativa pharmacological potential is linked to the large number of chemical substances present in its composition, the main class being called cannabinoids. Such compounds have numerous biological properties, such as antiemetic, neuroprotective, anti-inflammatory and anticancer activities, and may be beneficial on cancer pain treatment and psychological disorders. Currently, there is a drug in clinical use derived from cannabinoids being used to relieve cancer pain, but it is limited to Canada. It appears that perception of pain denotes a multidimensional phenomenon, which in cancer patients presents itself in a disabling way, with Cannabis sativa being a therapeutic possibility for the relief of pain levels. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-03-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384 10.32712/2446-4775.2022.1384 |
url |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384 |
identifier_str_mv |
10.32712/2446-4775.2022.1384 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1290 https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1291 https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384/1377 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Revista Fitos https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Revista Fitos https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf text/html text/xml |
dc.publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
publisher.none.fl_str_mv |
Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz |
dc.source.none.fl_str_mv |
Revista Fitos; Vol. 17 No. 1 (2023); 119-127 Revista Fitos; Vol. 17 Núm. 1 (2023); 119-127 Revista Fitos; v. 17 n. 1 (2023); 119-127 2446-4775 1808-9569 reponame:Revista Fitos instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
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FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Revista Fitos |
collection |
Revista Fitos |
repository.name.fl_str_mv |
Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br |
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