Cannabis sativa L. (cannabaceae): alternative for the treatment of oncological pain

• Autor(a) principal: Silva, Viviane Gomes da
• Data de Publicação: 2023
• Outros Autores: Silva, Kelvyn Kennedy de Figueiredo, Dantas, Bruna Braga
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1384
• topic: Cannabis sativa; Pain; Cancer patient; Cancer; Cannabis sativa; Dor; Paciente oncológico; Câncer

Cancer pain is a current problem of high prevalence and difficult to manage. Searching for new perspectives for the relief of pain levels in cancer patients, the use of cannabis appears as a therapeutic alternative. The objective was to highlight, through scientific evidence, the pharmacological potential of the Cannabis sativa L. (cannabaceae) plant on cancer pain treatment. A literature review was carried out using the following databases: SciELO, LILACS, Science Direct and PubMed, considering works published between 2007 and 2020. After applying the inclusion and exclusion criteria, 25 articles were selected. The results indicated that the Cannabis sativa pharmacological potential is linked to the large number of chemical substances present in its composition, the main class being called cannabinoids. Such compounds have numerous biological properties, such as antiemetic, neuroprotective, anti-inflammatory and anticancer activities, and may be beneficial on cancer pain treatment and psychological disorders. Currently, there is a drug in clinical use derived from cannabinoids being used to relieve cancer pain, but it is limited to Canada. It appears that perception of pain denotes a multidimensional phenomenon, which in cancer patients presents itself in a disabling way, with Cannabis sativa being a therapeutic possibility for the relief of pain levels.