Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae

Detalhes bibliográficos
Autor(a) principal: Maniafu,Barasa M
Data de Publicação: 2009
Outros Autores: Wilber,Lwande, Ndiege,Isaiah O, Wanjala,Cornelius C, Akenga,Teresa Ayuko
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002
Resumo: Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.
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spelling Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiaePlumbago zeylanicaPlumbago stenophyllaPlumbago daweilarvicidal activity5-hydroxy-2-methyl-1,4-naphthoquinoneAnopheles gambiaeThree Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.Instituto Oswaldo Cruz, Ministério da Saúde2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002Memórias do Instituto Oswaldo Cruz v.104 n.6 2009reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762009000600002info:eu-repo/semantics/openAccessManiafu,Barasa MWilber,LwandeNdiege,Isaiah OWanjala,Cornelius CAkenga,Teresa Ayukoeng2020-04-25T17:50:32Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:16:23.584Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
title Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
spellingShingle Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
Maniafu,Barasa M
Plumbago zeylanica
Plumbago stenophylla
Plumbago dawei
larvicidal activity
5-hydroxy-2-methyl-1,4-naphthoquinone
Anopheles gambiae
title_short Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
title_full Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
title_fullStr Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
title_full_unstemmed Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
title_sort Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
author Maniafu,Barasa M
author_facet Maniafu,Barasa M
Wilber,Lwande
Ndiege,Isaiah O
Wanjala,Cornelius C
Akenga,Teresa Ayuko
author_role author
author2 Wilber,Lwande
Ndiege,Isaiah O
Wanjala,Cornelius C
Akenga,Teresa Ayuko
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Maniafu,Barasa M
Wilber,Lwande
Ndiege,Isaiah O
Wanjala,Cornelius C
Akenga,Teresa Ayuko
dc.subject.por.fl_str_mv Plumbago zeylanica
Plumbago stenophylla
Plumbago dawei
larvicidal activity
5-hydroxy-2-methyl-1,4-naphthoquinone
Anopheles gambiae
topic Plumbago zeylanica
Plumbago stenophylla
Plumbago dawei
larvicidal activity
5-hydroxy-2-methyl-1,4-naphthoquinone
Anopheles gambiae
dc.description.none.fl_txt_mv Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.
description Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762009000600002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.104 n.6 2009
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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