Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002 |
Resumo: | Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature. |
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Memórias do Instituto Oswaldo Cruz |
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Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiaePlumbago zeylanicaPlumbago stenophyllaPlumbago daweilarvicidal activity5-hydroxy-2-methyl-1,4-naphthoquinoneAnopheles gambiaeThree Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature.Instituto Oswaldo Cruz, Ministério da Saúde2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002Memórias do Instituto Oswaldo Cruz v.104 n.6 2009reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762009000600002info:eu-repo/semantics/openAccessManiafu,Barasa MWilber,LwandeNdiege,Isaiah OWanjala,Cornelius CAkenga,Teresa Ayukoeng2020-04-25T17:50:32Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:16:23.584Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
title |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
spellingShingle |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae Maniafu,Barasa M Plumbago zeylanica Plumbago stenophylla Plumbago dawei larvicidal activity 5-hydroxy-2-methyl-1,4-naphthoquinone Anopheles gambiae |
title_short |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
title_full |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
title_fullStr |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
title_full_unstemmed |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
title_sort |
Larvicidal activity of extracts from three Plumbago spp against Anopheles gambiae |
author |
Maniafu,Barasa M |
author_facet |
Maniafu,Barasa M Wilber,Lwande Ndiege,Isaiah O Wanjala,Cornelius C Akenga,Teresa Ayuko |
author_role |
author |
author2 |
Wilber,Lwande Ndiege,Isaiah O Wanjala,Cornelius C Akenga,Teresa Ayuko |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Maniafu,Barasa M Wilber,Lwande Ndiege,Isaiah O Wanjala,Cornelius C Akenga,Teresa Ayuko |
dc.subject.por.fl_str_mv |
Plumbago zeylanica Plumbago stenophylla Plumbago dawei larvicidal activity 5-hydroxy-2-methyl-1,4-naphthoquinone Anopheles gambiae |
topic |
Plumbago zeylanica Plumbago stenophylla Plumbago dawei larvicidal activity 5-hydroxy-2-methyl-1,4-naphthoquinone Anopheles gambiae |
dc.description.none.fl_txt_mv |
Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature. |
description |
Three Plumbago spp have been tested for mosquito larvicidal activity. The crude extracts exhibiting the highest larvicidal activity against Anopheles gambiae were hexane (LC50 = 6.4 μg/mL) and chloroform (LC50 = 6.7 μg/mL) extracts from Plumbago zeylanica Linn, chloroform (LC50 = 6.7 ug/mL) extract from Plumbago stenophylla Bull and ethyl acetate (LC50 = 4.1 μg/mL) extract from Plumbago dawei Rolfe. These LC50 values were within 95% confidence limits. 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin) 1 (LC50 = 1.9 μg/mL) and β-sitosterol 2 were characterised from ethyl acetate extract of root bark of P. dawei, a native medicinal plant growing in Kenya, based on spectral analysis and comparisons with data in literature. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000600002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0074-02762009000600002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.104 n.6 2009 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
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1669937705550610432 |