The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644 |
Resumo: | Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission. |
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Memórias do Instituto Oswaldo Cruz |
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The Plasmodium bottleneck: malaria parasite losses in the mosquito vectormalariamosquitoPlasmodiuminnateimmunityNearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission.Instituto Oswaldo Cruz, Ministério da Saúde2014-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644Memórias do Instituto Oswaldo Cruz v.109 n.5 2014reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-0276130597info:eu-repo/semantics/openAccessSmith,Ryan CVega-Rodríguez,JoelJacobs-Lorena,Marceloeng2020-04-25T17:51:46Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:19:45.824Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
title |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
spellingShingle |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector Smith,Ryan C malaria mosquito Plasmodium innate immunity |
title_short |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
title_full |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
title_fullStr |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
title_full_unstemmed |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
title_sort |
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector |
author |
Smith,Ryan C |
author_facet |
Smith,Ryan C Vega-Rodríguez,Joel Jacobs-Lorena,Marcelo |
author_role |
author |
author2 |
Vega-Rodríguez,Joel Jacobs-Lorena,Marcelo |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Smith,Ryan C Vega-Rodríguez,Joel Jacobs-Lorena,Marcelo |
dc.subject.por.fl_str_mv |
malaria mosquito Plasmodium innate immunity |
topic |
malaria mosquito Plasmodium innate immunity |
dc.description.none.fl_txt_mv |
Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission. |
description |
Nearly one million people are killed every year by the malaria parasite Plasmodium. Although the disease-causing forms of the parasite exist only in the human blood, mosquitoes of the genus Anopheles are the obligate vector for transmission. Here, we review the parasite life cycle in the vector and highlight the human and mosquito contributions that limit malaria parasite development in the mosquito host. We address parasite killing in its mosquito host and bottlenecks in parasite numbers that might guide intervention strategies to prevent transmission. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000500644 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0074-0276130597 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.109 n.5 2014 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
_version_ |
1669937716074119168 |