The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Cadernos de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000200005 |
Resumo: | We investigated the impact of multidrug therapy (MDT) on the epidemiological pattern of leprosy in Juiz de Fora, Brazil, from 1978 to 1995. Evaluation of 1,283 medical charts was performed according to the treatment regimen used in two different periods. Following the introduction of MDT in 1987, prevalence of leprosy decreased from 22 patients/10,000 inhabitants to 5.2 patients/10,000 inhabitants in 1995. Incidence rate of leprosy was lower in period II (1987-1995) than in period I (1978-1986). Decreasing prevalence and incidence appear to be related to drug efficacy rather than decreased case identification, since both self-referred and professionally referred treatment increased markedly from period I to period II. For both periods, multibacillary leprosy was the most frequent clinical form of the disease (±68%), and the main infection risk factor identified was household contact. Leprosy is predominantly manifested in adults, but an increase in the number of very old and very young patients was observed in period II. The MDT program has been effective both in combating leprosy and in promoting awareness of the disease. |
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The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, BrazilLeprosyCombination Drug TherapyPrevalenceEpidemiologyWe investigated the impact of multidrug therapy (MDT) on the epidemiological pattern of leprosy in Juiz de Fora, Brazil, from 1978 to 1995. Evaluation of 1,283 medical charts was performed according to the treatment regimen used in two different periods. Following the introduction of MDT in 1987, prevalence of leprosy decreased from 22 patients/10,000 inhabitants to 5.2 patients/10,000 inhabitants in 1995. Incidence rate of leprosy was lower in period II (1987-1995) than in period I (1978-1986). Decreasing prevalence and incidence appear to be related to drug efficacy rather than decreased case identification, since both self-referred and professionally referred treatment increased markedly from period I to period II. For both periods, multibacillary leprosy was the most frequent clinical form of the disease (±68%), and the main infection risk factor identified was household contact. Leprosy is predominantly manifested in adults, but an increase in the number of very old and very young patients was observed in period II. The MDT program has been effective both in combating leprosy and in promoting awareness of the disease.Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz2000-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000200005Cadernos de Saúde Pública v.16 n.2 2000reponame:Cadernos de Saúde Públicainstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZ10.1590/S0102-311X2000000200005info:eu-repo/semantics/openAccessSoares,Luzivander S.Moreira,Rodrigo de O.Vilela,Vanessa V.Alves,Márcio J. M.Pimentel,Ana Flávia M.Ferreira,Ana PaulaTeixeira,Henrique C.eng2001-08-15T00:00:00Zoai:scielo:S0102-311X2000000200005Revistahttp://cadernos.ensp.fiocruz.br/csp/https://old.scielo.br/oai/scielo-oai.phpcadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br1678-44640102-311Xopendoar:2001-08-15T00:00Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.none.fl_str_mv |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
title |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
spellingShingle |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil Soares,Luzivander S. Leprosy Combination Drug Therapy Prevalence Epidemiology |
title_short |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
title_full |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
title_fullStr |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
title_full_unstemmed |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
title_sort |
The impact of multidrug therapy on the epidemiological pattern of leprosy in Juiz de Fora, Brazil |
author |
Soares,Luzivander S. |
author_facet |
Soares,Luzivander S. Moreira,Rodrigo de O. Vilela,Vanessa V. Alves,Márcio J. M. Pimentel,Ana Flávia M. Ferreira,Ana Paula Teixeira,Henrique C. |
author_role |
author |
author2 |
Moreira,Rodrigo de O. Vilela,Vanessa V. Alves,Márcio J. M. Pimentel,Ana Flávia M. Ferreira,Ana Paula Teixeira,Henrique C. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Soares,Luzivander S. Moreira,Rodrigo de O. Vilela,Vanessa V. Alves,Márcio J. M. Pimentel,Ana Flávia M. Ferreira,Ana Paula Teixeira,Henrique C. |
dc.subject.por.fl_str_mv |
Leprosy Combination Drug Therapy Prevalence Epidemiology |
topic |
Leprosy Combination Drug Therapy Prevalence Epidemiology |
description |
We investigated the impact of multidrug therapy (MDT) on the epidemiological pattern of leprosy in Juiz de Fora, Brazil, from 1978 to 1995. Evaluation of 1,283 medical charts was performed according to the treatment regimen used in two different periods. Following the introduction of MDT in 1987, prevalence of leprosy decreased from 22 patients/10,000 inhabitants to 5.2 patients/10,000 inhabitants in 1995. Incidence rate of leprosy was lower in period II (1987-1995) than in period I (1978-1986). Decreasing prevalence and incidence appear to be related to drug efficacy rather than decreased case identification, since both self-referred and professionally referred treatment increased markedly from period I to period II. For both periods, multibacillary leprosy was the most frequent clinical form of the disease (±68%), and the main infection risk factor identified was household contact. Leprosy is predominantly manifested in adults, but an increase in the number of very old and very young patients was observed in period II. The MDT program has been effective both in combating leprosy and in promoting awareness of the disease. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000200005 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2000000200005 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0102-311X2000000200005 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
publisher.none.fl_str_mv |
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz |
dc.source.none.fl_str_mv |
Cadernos de Saúde Pública v.16 n.2 2000 reponame:Cadernos de Saúde Pública instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Cadernos de Saúde Pública |
collection |
Cadernos de Saúde Pública |
repository.name.fl_str_mv |
Cadernos de Saúde Pública - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
cadernos@ensp.fiocruz.br||cadernos@ensp.fiocruz.br |
_version_ |
1754115719607353344 |