Serologic survey for hantavirus infections among wild animals in rural areas of São Paulo State, Brazil

• Autor(a) principal: ROMANO-LIEBER, Nicolina Silvana
• Data de Publicação: 2001
• Outros Autores: YEE, Joyce, HJELLE, Brian
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista do Instituto de Medicina Tropical de São Paulo
• Texto Completo: https://www.revistas.usp.br/rimtsp/article/view/30558
• topic: Hantavirus pulmonary syndrome; Hantavirus cardiopulmonary syndrome(HCPS); Reservoirs; Strip immunoblot assay (SIA); Reverse transcriptase-polymerase chain reaction (RT-PCR); Araraquara; Iguape

A serosurvey was conducted in wild animals captured close to two areas where hantavirus cardiopulmonary syndrome (HCPS) occurred in São Paulo State, Brazil. Serum samples from a total of 43 mammals were tested for antibodies reactive with Sin Nombre (SN) hantavirus using a strip immunoblot assay. RNAs from the blood clots of the positive samples were submitted to reverse transcriptase-polymerase chain reaction (RT-PCR). Two rodents of the genus Oligoryzomys were positive for hantavirus antibodies. These animals were captured in the Iguape region and represented 16.7% (2/12) of the sera from rodents and 100.0% (2/2) of the Oligoryzomys captured in that area. RT-PCR failed to amplify any viral cDNA. These results are in agreement with other data that suggest that members of this genus are important reservoirs of hantaviruses in Brazil.