O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da Uninove |
Texto Completo: | http://bibliotecatede.uninove.br/handle/tede/1811 |
Resumo: | The cerebral palsy (CP) is characterized by a group of non progressive disorders of the brain???s development and posture caused by a malformation or brain injury. As treatment , there are therapeutic approaches aimed at normalizing muscle tone and prevent change in the relation between bone growth and muscle, that can lead to poor posture and structured deformities. The aim this study was to investigate the effects of botulinum toxin type A (TB-A) for spasticity and functionality in spastic CP childrem. This was a prospective, controlled, randomized, consisting of 24 children (aged 5 to 12 years) with spastic CP, being divided into two groups: experimental group (EG) consisting of 12 patients (mean age 7.83 ?? 2, 07 years) treated with TB-A toxin and physiotherapy and control group (CG) with 12 patients (mean age 8.50 ?? 2.17 years) treated only with physical therapy. All participants were assessed through motor and functional scales (GMFCS, GMFM-88, Ashworth, Berg Balance Scale, Time up and go -TUG and Inventory Assessment Pediatric Disorders - ASK) at three different times: before treatment, 30 days and 3 months after the treatment proposed. By analysis of variance (ANOVA) for repeated measures it was observed significant differences (p < 0.001) between groups (groups vs treatment) to the data obtained in the GMFCS, GMFM-88, BERG, TUG, Ashworth and ASK, being observed functional improvement only for the GE group. In this study it was concluded that the use of TB-A provides a significant improvement on spasticity and child functionality with spastic CP, over a period of up to 3 months after application. |
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Politti, FabianoOliveira, Claudia SantosPolitti, FabianoCorrea, Fernanda IshidaMonteiro, Carlos Bandeira de Melohttp://lattes.cnpq.br/4218320238770892Souza, Maria Eliege de2018-06-19T15:38:25Z2015-12-14Souza, Maria Eliege de. O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica. 2015. 85 f. Disserta????o( Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o) - Universidade Nove de Julho, S??o Paulo.http://bibliotecatede.uninove.br/handle/tede/1811The cerebral palsy (CP) is characterized by a group of non progressive disorders of the brain???s development and posture caused by a malformation or brain injury. As treatment , there are therapeutic approaches aimed at normalizing muscle tone and prevent change in the relation between bone growth and muscle, that can lead to poor posture and structured deformities. The aim this study was to investigate the effects of botulinum toxin type A (TB-A) for spasticity and functionality in spastic CP childrem. This was a prospective, controlled, randomized, consisting of 24 children (aged 5 to 12 years) with spastic CP, being divided into two groups: experimental group (EG) consisting of 12 patients (mean age 7.83 ?? 2, 07 years) treated with TB-A toxin and physiotherapy and control group (CG) with 12 patients (mean age 8.50 ?? 2.17 years) treated only with physical therapy. All participants were assessed through motor and functional scales (GMFCS, GMFM-88, Ashworth, Berg Balance Scale, Time up and go -TUG and Inventory Assessment Pediatric Disorders - ASK) at three different times: before treatment, 30 days and 3 months after the treatment proposed. By analysis of variance (ANOVA) for repeated measures it was observed significant differences (p < 0.001) between groups (groups vs treatment) to the data obtained in the GMFCS, GMFM-88, BERG, TUG, Ashworth and ASK, being observed functional improvement only for the GE group. In this study it was concluded that the use of TB-A provides a significant improvement on spasticity and child functionality with spastic CP, over a period of up to 3 months after application.A Paralisia Cerebral (PC) ?? caracterizada por um grupo n??o progressivo de desordens do desenvolvimento e postura decorrentes de uma malforma????o ou les??o cerebral. Como tratamento, destacam-se abordagens terap??uticas que visam normalizar o t??nus muscular e prevenir altera????o na rela????o entre o crescimento ??sseo e o muscular, que podem provocar posturas inadequadas e deformidades estruturadas. Dessa maneira, o objetivo desse estudo foi verificar os efeitos da toxina botul??nica tipo A (TB-A) sobre a espasticidade e funcionalidade da crian??a com PC esp??stica. Esse foi um estudo prospectivo, controlado, randomizado, constitu??do por 24 crian??as (idade entre 5 e 12 anos) com PC esp??stica, distribu??das em dois grupos sendo: Grupo experimental (GE) constitu??do com 12 pacientes (idade m??dia 7,83 ??? 2,07 anos) tratadas com toxina TB-A e fisioterapia e Grupo controle (GC) sendo 12 pacientes (idade m??dia 8,50 ??? 2,17 anos) tratados somente com fisioterapia. Todos os participantes foram avaliados por meio de escalas motoras e funcionais (GMFCS, GMFM-88, Ashworth, escala de equil??brio de BERG, Time up and go ???TUG e o Invent??rio de Avalia????o Pedi??trica de Disfun????es - PEDI) em tr??s momentos distintos: antes do tratamento, 30 dias e 3 meses ap??s o tratamento proposto. Por meio da an??lise de vari??ncia (ANOVA) para medidas repetidas foi poss??vel observar diferen??as significativas (p < 0,001) entre os grupos (grupos vs tratamento) para os dados obtidos na escala de GMFCS, GMFM-88, BERG, TUG, Ashworth e PEDI, sendo observada melhora funcional somente para o grupo GE. Nesse estudo foi poss??vel concluir que o uso da TB-A proporciona uma melhora significativa sobre a espasticidade e funcionalidade da crian??a com PC esp??stica, em um per??odo de at?? 3 meses ap??s sua aplica????o.Submitted by Nadir Basilio (nadirsb@uninove.br) on 2018-06-19T15:38:25Z No. of bitstreams: 1 Maria Eliege de Souza.pdf: 1276931 bytes, checksum: dc49846f1db7db8cc9034d54ff988caf (MD5)Made available in DSpace on 2018-06-19T15:38:25Z (GMT). No. of bitstreams: 1 Maria Eliege de Souza.pdf: 1276931 bytes, checksum: dc49846f1db7db8cc9034d54ff988caf (MD5) Previous issue date: 2015-12-14application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Ci??ncias da Reabilita????oUNINOVEBrasilSa??deparalisia cerebralfuncionalidadetoxina botul??nica Afisioterapiacerebral palsyfunctionalityphysiotherapybotulinum toxin type ACIENCIAS DA SAUDEO efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??sticaThe effect of type A toxin on spasticity and functionality on children with spastic cerebral palsyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALMaria Eliege de Souza.pdfMaria Eliege de Souza.pdfapplication/pdf1276931http://localhost:8080/tede/bitstream/tede/1811/2/Maria+Eliege+de+Souza.pdfdc49846f1db7db8cc9034d54ff988cafMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/1811/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/18112018-06-19 12:38:25.849oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2018-06-19T15:38:25Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false |
dc.title.por.fl_str_mv |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
dc.title.alternative.eng.fl_str_mv |
The effect of type A toxin on spasticity and functionality on children with spastic cerebral palsy |
title |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
spellingShingle |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica Souza, Maria Eliege de paralisia cerebral funcionalidade toxina botul??nica A fisioterapia cerebral palsy functionality physiotherapy botulinum toxin type A CIENCIAS DA SAUDE |
title_short |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
title_full |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
title_fullStr |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
title_full_unstemmed |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
title_sort |
O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica |
author |
Souza, Maria Eliege de |
author_facet |
Souza, Maria Eliege de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Politti, Fabiano |
dc.contributor.advisor-co1.fl_str_mv |
Oliveira, Claudia Santos |
dc.contributor.referee1.fl_str_mv |
Politti, Fabiano |
dc.contributor.referee2.fl_str_mv |
Correa, Fernanda Ishida |
dc.contributor.referee3.fl_str_mv |
Monteiro, Carlos Bandeira de Melo |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/4218320238770892 |
dc.contributor.author.fl_str_mv |
Souza, Maria Eliege de |
contributor_str_mv |
Politti, Fabiano Oliveira, Claudia Santos Politti, Fabiano Correa, Fernanda Ishida Monteiro, Carlos Bandeira de Melo |
dc.subject.por.fl_str_mv |
paralisia cerebral funcionalidade toxina botul??nica A fisioterapia |
topic |
paralisia cerebral funcionalidade toxina botul??nica A fisioterapia cerebral palsy functionality physiotherapy botulinum toxin type A CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
cerebral palsy functionality physiotherapy botulinum toxin type A |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
The cerebral palsy (CP) is characterized by a group of non progressive disorders of the brain???s development and posture caused by a malformation or brain injury. As treatment , there are therapeutic approaches aimed at normalizing muscle tone and prevent change in the relation between bone growth and muscle, that can lead to poor posture and structured deformities. The aim this study was to investigate the effects of botulinum toxin type A (TB-A) for spasticity and functionality in spastic CP childrem. This was a prospective, controlled, randomized, consisting of 24 children (aged 5 to 12 years) with spastic CP, being divided into two groups: experimental group (EG) consisting of 12 patients (mean age 7.83 ?? 2, 07 years) treated with TB-A toxin and physiotherapy and control group (CG) with 12 patients (mean age 8.50 ?? 2.17 years) treated only with physical therapy. All participants were assessed through motor and functional scales (GMFCS, GMFM-88, Ashworth, Berg Balance Scale, Time up and go -TUG and Inventory Assessment Pediatric Disorders - ASK) at three different times: before treatment, 30 days and 3 months after the treatment proposed. By analysis of variance (ANOVA) for repeated measures it was observed significant differences (p < 0.001) between groups (groups vs treatment) to the data obtained in the GMFCS, GMFM-88, BERG, TUG, Ashworth and ASK, being observed functional improvement only for the GE group. In this study it was concluded that the use of TB-A provides a significant improvement on spasticity and child functionality with spastic CP, over a period of up to 3 months after application. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-12-14 |
dc.date.accessioned.fl_str_mv |
2018-06-19T15:38:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Souza, Maria Eliege de. O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica. 2015. 85 f. Disserta????o( Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o) - Universidade Nove de Julho, S??o Paulo. |
dc.identifier.uri.fl_str_mv |
http://bibliotecatede.uninove.br/handle/tede/1811 |
identifier_str_mv |
Souza, Maria Eliege de. O efeito da toxina botul??nica tipo A sobre a espasticidade e funcionalidade da crian??a com paralisia cerebral esp??stica. 2015. 85 f. Disserta????o( Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o) - Universidade Nove de Julho, S??o Paulo. |
url |
http://bibliotecatede.uninove.br/handle/tede/1811 |
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por |
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por |
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8765449414823306929 |
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openAccess |
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Universidade Nove de Julho |
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Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o |
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UNINOVE |
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Brasil |
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Universidade Nove de Julho |
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