Fatty acids as biological markers of fat intake

• Autor(a) principal: dos Santos VAZ, Juliana
• Data de Publicação: 2023
• Outros Autores: DEBONI, Fabíola, de AZEVEDO, Mirela Jobim, GROSS, Jorge Luiz, ZELMANOVITZ, Themis
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista de Nutrição
• Texto Completo: https://periodicos.puc-campinas.edu.br/nutricao/article/view/9762
• topic: fatty acids; diet; lipids; biological markers; adipose tissue; ácidos graxos; dieta; lipídeos; marcadores biológicos; tecido adiposo

Dietary fatty acids have been associated with the development of chronic diseases. The methods commonlyused in dietary assessment for estimating nutrient intake in clinical and epidemiological studies presentlimitations regarding data collection. The use of plasma and adipose tissue fatty acid composition as markersof the type of fat ingested has been studied and can provide a more accurate measurement of dietary fatintake. The aim of this study is to evidence the metabolic aspects of some fatty acids and their role as markersof dietary fat intake, and to present the analytical methods used in their determination. Analysis of the fattyacid composition of adipose tissue provides long-term information on dietary fat intake, whereas the determination of the fatty acid composition of serum lipid fractions accounts for the short- and medium-termdietary intakes. The essential fatty acids, the saturated fatty acids with an odd number of carbon atoms (15:0and 17:0) and the trans fatty acids are used as biological markers of dietary fat intake or of these individualcomponents, since they are not synthesized endogenously. Gas chromatography and high-performance liquidchromatography are the main analytical methods used to determine fatty acid composition. At present, themost comprehensive evaluation of dietary fat intake comprises the determination of biological markers inassociation with dietary assessment methods.