Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/4693 |
Resumo: | We present a case study of a 5-year-old patient, who presented with left-sided torticollis. Due to persistence of problems, a CT and an MRI were made showing a single osteolytic lesion centred on right occipital condyle. After an open biopsy, histology confirmed it to be Langerhans cell histiocytosis (LCH). Torticollis or restricted range of motion is a presenting feature in 76% of children with LCH with cervical involvement. There remains much debate on the best treatment strategy. The clinical and radiological outcomes of the case study presented on this article support the treatment of LCH with chemotherapy in cases with solitary involvement of the occipital condyle. |
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Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the LiteratureChild, PreschoolHistiocytosis, Langerhans-Cell / complicationsHistiocytosis, Langerhans-Cell / diagnosisHistiocytosis, Langerhans-Cell / surgeryMagnetic Resonance ImagingNeck Pain / etiologyOccipital Bone / diagnostic imagingOccipital Bone / pathology*Occipital Bone / surgeryRadionuclide ImagingTomography, X-Ray ComputedTorticollis / etiologyHDE NCIRWe present a case study of a 5-year-old patient, who presented with left-sided torticollis. Due to persistence of problems, a CT and an MRI were made showing a single osteolytic lesion centred on right occipital condyle. After an open biopsy, histology confirmed it to be Langerhans cell histiocytosis (LCH). Torticollis or restricted range of motion is a presenting feature in 76% of children with LCH with cervical involvement. There remains much debate on the best treatment strategy. The clinical and radiological outcomes of the case study presented on this article support the treatment of LCH with chemotherapy in cases with solitary involvement of the occipital condyle.BMJRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEBarbosa, NCRamos, ASagarribay, ARibeiro, MJ2023-09-11T12:18:52Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/4693engBMJ Case Rep . 2020 Dec 12;13(12):e23563010.1136/bcr-2020-235630info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-09-17T06:26:50Zoai:repositorio.chlc.min-saude.pt:10400.17/4693Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:29:29.367559Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
title |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
spellingShingle |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature Barbosa, NC Child, Preschool Histiocytosis, Langerhans-Cell / complications Histiocytosis, Langerhans-Cell / diagnosis Histiocytosis, Langerhans-Cell / surgery Magnetic Resonance Imaging Neck Pain / etiology Occipital Bone / diagnostic imaging Occipital Bone / pathology* Occipital Bone / surgery Radionuclide Imaging Tomography, X-Ray Computed Torticollis / etiology HDE NCIR |
title_short |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
title_full |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
title_fullStr |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
title_full_unstemmed |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
title_sort |
Langerhans Cell Histiocytosis in the Occipital Condyle: A Case Study and a Brief Review of the Literature |
author |
Barbosa, NC |
author_facet |
Barbosa, NC Ramos, A Sagarribay, A Ribeiro, MJ |
author_role |
author |
author2 |
Ramos, A Sagarribay, A Ribeiro, MJ |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Barbosa, NC Ramos, A Sagarribay, A Ribeiro, MJ |
dc.subject.por.fl_str_mv |
Child, Preschool Histiocytosis, Langerhans-Cell / complications Histiocytosis, Langerhans-Cell / diagnosis Histiocytosis, Langerhans-Cell / surgery Magnetic Resonance Imaging Neck Pain / etiology Occipital Bone / diagnostic imaging Occipital Bone / pathology* Occipital Bone / surgery Radionuclide Imaging Tomography, X-Ray Computed Torticollis / etiology HDE NCIR |
topic |
Child, Preschool Histiocytosis, Langerhans-Cell / complications Histiocytosis, Langerhans-Cell / diagnosis Histiocytosis, Langerhans-Cell / surgery Magnetic Resonance Imaging Neck Pain / etiology Occipital Bone / diagnostic imaging Occipital Bone / pathology* Occipital Bone / surgery Radionuclide Imaging Tomography, X-Ray Computed Torticollis / etiology HDE NCIR |
description |
We present a case study of a 5-year-old patient, who presented with left-sided torticollis. Due to persistence of problems, a CT and an MRI were made showing a single osteolytic lesion centred on right occipital condyle. After an open biopsy, histology confirmed it to be Langerhans cell histiocytosis (LCH). Torticollis or restricted range of motion is a presenting feature in 76% of children with LCH with cervical involvement. There remains much debate on the best treatment strategy. The clinical and radiological outcomes of the case study presented on this article support the treatment of LCH with chemotherapy in cases with solitary involvement of the occipital condyle. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2023-09-11T12:18:52Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/4693 |
url |
http://hdl.handle.net/10400.17/4693 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMJ Case Rep . 2020 Dec 12;13(12):e235630 10.1136/bcr-2020-235630 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMJ |
publisher.none.fl_str_mv |
BMJ |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133562588364800 |