Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications

Detalhes bibliográficos
Autor(a) principal: Freitas, Rafaela
Data de Publicação: 2020
Outros Autores: Martins, Alice, Silva, Joana, Alves, Celso, Pinteus, Susete, Alves, Joana, Teodoro, Fernando, Ribeiro, Helena Margarida, Gonçalves, Lídia, Petrovski, Željko, Branco, Luís, Pedrosa, Rui
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/115253
Resumo: UID/MAR/04292/2020 PTDC/MAR-BIO/6149/2014 POCI-01-0145-FEDER-016791 SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405 PTDC/BIA-OUT/29250/2017 POCI-01-0145-FEDER-029250 Centro-01-0145-FEDER-000018
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spelling Highlighting the biological potential of the brown seaweed fucus spiralis for skin applicationsAnti-enzymaticAnti-inflammatoryAntioxidantDermo-cosmeticsFucus spiralisOxidative stressPhotoprotectiveSeaweedsSkin microbiomeBiochemistryPhysiologyMolecular BiologyClinical BiochemistryCell BiologyUID/MAR/04292/2020 PTDC/MAR-BIO/6149/2014 POCI-01-0145-FEDER-016791 SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405 PTDC/BIA-OUT/29250/2017 POCI-01-0145-FEDER-029250 Centro-01-0145-FEDER-000018Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matrix, also enhanced by enzymatic degradation of matrix supporting molecules. Thus, and with the growing demand for eco-friendly skin products, natural compounds extracted from brown seaweeds revealed to be good candidates due to their broad range of bioactivities, especially as antioxidants. The aim of this study was to assess the dermo-cosmetic potential of different fractions obtained from the brown seaweed Fucus spiralis. For this purpose, in vitro antioxidant (Total Phenolic Content (TPC), 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, Ferric Reducing Antioxidant Power (FRAP), Oxygen Radical Absorbance Capacity (ORAC)), anti-enzymatic (collagenase, elastase and hyaluronidase), antimicrobial, anti-inflammatory (NO production) and photoprotective (ROS production) capacities were evaluated. Although nearly all fractions evidenced antioxidant effects, fraction F10 demonstrated the highest antioxidant ability (EC50 of 38.5 µg/mL, DPPH assay), and exhibited a strong effect as an inhibitor of collagenase (0.037 µg/mL) and elastase (3.0 µg/mL). Moreover, this fraction was also the most potent on reducing ROS production promoted by H2O2 (IC50 of 41.3 µg/mL) and by UVB (IC50 of 31.3 µg/mL). These bioactivities can be attributed to its high content of phlorotannins, as evaluated by LC-MS analysis, reinforcing the potential of F. spiralis for further dermatological applications.DQ - Departamento de QuímicaLAQV@REQUIMTERUNFreitas, RafaelaMartins, AliceSilva, JoanaAlves, CelsoPinteus, SuseteAlves, JoanaTeodoro, FernandoRibeiro, Helena MargaridaGonçalves, LídiaPetrovski, ŽeljkoBranco, LuísPedrosa, Rui2021-04-08T22:17:40Z2020-07-112020-07-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article21application/pdfhttp://hdl.handle.net/10362/115253eng2076-3921PURE: 29101406https://doi.org/10.3390/antiox9070611info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:57:53Zoai:run.unl.pt:10362/115253Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:43.636964Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
title Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
spellingShingle Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
Freitas, Rafaela
Anti-enzymatic
Anti-inflammatory
Antioxidant
Dermo-cosmetics
Fucus spiralis
Oxidative stress
Photoprotective
Seaweeds
Skin microbiome
Biochemistry
Physiology
Molecular Biology
Clinical Biochemistry
Cell Biology
title_short Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
title_full Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
title_fullStr Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
title_full_unstemmed Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
title_sort Highlighting the biological potential of the brown seaweed fucus spiralis for skin applications
author Freitas, Rafaela
author_facet Freitas, Rafaela
Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Željko
Branco, Luís
Pedrosa, Rui
author_role author
author2 Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Željko
Branco, Luís
Pedrosa, Rui
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv DQ - Departamento de Química
LAQV@REQUIMTE
RUN
dc.contributor.author.fl_str_mv Freitas, Rafaela
Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Željko
Branco, Luís
Pedrosa, Rui
dc.subject.por.fl_str_mv Anti-enzymatic
Anti-inflammatory
Antioxidant
Dermo-cosmetics
Fucus spiralis
Oxidative stress
Photoprotective
Seaweeds
Skin microbiome
Biochemistry
Physiology
Molecular Biology
Clinical Biochemistry
Cell Biology
topic Anti-enzymatic
Anti-inflammatory
Antioxidant
Dermo-cosmetics
Fucus spiralis
Oxidative stress
Photoprotective
Seaweeds
Skin microbiome
Biochemistry
Physiology
Molecular Biology
Clinical Biochemistry
Cell Biology
description UID/MAR/04292/2020 PTDC/MAR-BIO/6149/2014 POCI-01-0145-FEDER-016791 SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405 PTDC/BIA-OUT/29250/2017 POCI-01-0145-FEDER-029250 Centro-01-0145-FEDER-000018
publishDate 2020
dc.date.none.fl_str_mv 2020-07-11
2020-07-11T00:00:00Z
2021-04-08T22:17:40Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/115253
url http://hdl.handle.net/10362/115253
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2076-3921
PURE: 29101406
https://doi.org/10.3390/antiox9070611
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 21
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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