Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications

Detalhes bibliográficos
Autor(a) principal: Freitas, Rafaela
Data de Publicação: 2020
Outros Autores: Martins, Alice, Silva, Joana, Alves, Celso, Pinteus, Susete, Alves, Joana, Teodoro, Fernando, Ribeiro, Helena Margarida, Gonçalves, Lídia, Petrovski, Zeljko, Branco, Luís, Pedrosa, Rui
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.8/5113
Resumo: Funding: This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre, through Red2Discovery project (PTDC/MAR-BIO/6149/2014), co-financed by COMPETE (POCI-01-0145-FEDER-016791), through Oncologia de Precisão: Terapias e Tecnologias Inovadoras project (POINT4PAC) (SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405) and through CrossAtlantic project (PTDC/BIA-OUT/29250/2017), co-financed by COMPETE (POCI-01-0145-FEDER-029250). This work was also funded by the Integrated Programme of SR&TD Smart Valorization of Endogenous Marine Biological Resources Under a Changing Climate (Centro-01-0145-FEDER-000018), co-funded by Centro 2020 Programme, Portugal 2020, European Union, through the European Regional Development Fund.
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spelling Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applicationsFucus spiralisSeaweedsAntioxidantOxidative stressPhotoprotectiveAnti-enzymaticAnti-inflammatorySkin microbiomeDermo-cosmeticsFunding: This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre, through Red2Discovery project (PTDC/MAR-BIO/6149/2014), co-financed by COMPETE (POCI-01-0145-FEDER-016791), through Oncologia de Precisão: Terapias e Tecnologias Inovadoras project (POINT4PAC) (SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405) and through CrossAtlantic project (PTDC/BIA-OUT/29250/2017), co-financed by COMPETE (POCI-01-0145-FEDER-029250). This work was also funded by the Integrated Programme of SR&TD Smart Valorization of Endogenous Marine Biological Resources Under a Changing Climate (Centro-01-0145-FEDER-000018), co-funded by Centro 2020 Programme, Portugal 2020, European Union, through the European Regional Development Fund.Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matrix, also enhanced by enzymatic degradation of matrix supporting molecules. Thus, and with the growing demand for eco-friendly skin products, natural compounds extracted from brown seaweeds revealed to be good candidates due to their broad range of bioactivities, especially as antioxidants. The aim of this study was to assess the dermo-cosmetic potential of di erent fractions obtained from the brown seaweed Fucus spiralis. For this purpose, in vitro antioxidant (Total Phenolic Content (TPC), 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, Ferric Reducing Antioxidant Power (FRAP), Oxygen Radical Absorbance Capacity (ORAC)), anti-enzymatic (collagenase, elastase and hyaluronidase), antimicrobial, anti-inflammatory (NO production) and photoprotective (ROS production) capacities were evaluated. Although nearly all fractions evidenced antioxidant e ects, fraction F10 demonstrated the highest antioxidant ability (EC50 of 38.5 g/mL, DPPH assay), and exhibited a strong e ect as an inhibitor of collagenase (0.037 g/mL) and elastase (3.0 g/mL). Moreover, this fraction was also the most potent on reducing ROS production promoted by H2O2 (IC50 of 41.3 g/mL) and by UVB (IC50 of 31.3 g/mL). These bioactivities can be attributed to its high content of phlorotannins, as evaluated by LC-MS analysis, reinforcing the potential of F. spiralis for further dermatological applications.MDPIIC-OnlineFreitas, RafaelaMartins, AliceSilva, JoanaAlves, CelsoPinteus, SuseteAlves, JoanaTeodoro, FernandoRibeiro, Helena MargaridaGonçalves, LídiaPetrovski, ZeljkoBranco, LuísPedrosa, Rui2020-08-28T11:11:19Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.8/5113engFreitas, R., Martins, A., Silva, J., Alves, C., Pinteus, S., Alves, J., Teodoro, F., Ribeiro, H. M., Gonçalves, L., Petrovski, Ž., Branco, L., & Pedrosa, R. (2020). Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications. Antioxidants (Basel, Switzerland), 9(7), 611. https://doi.org/10.3390/antiox90706112076-392110.3390/antiox9070611info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-17T15:50:39Zoai:iconline.ipleiria.pt:10400.8/5113Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:48:47.425624Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
title Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
spellingShingle Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
Freitas, Rafaela
Fucus spiralis
Seaweeds
Antioxidant
Oxidative stress
Photoprotective
Anti-enzymatic
Anti-inflammatory
Skin microbiome
Dermo-cosmetics
title_short Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
title_full Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
title_fullStr Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
title_full_unstemmed Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
title_sort Highlighting the biological potential of the brown seaweed Fucus spiralis for skin applications
author Freitas, Rafaela
author_facet Freitas, Rafaela
Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Zeljko
Branco, Luís
Pedrosa, Rui
author_role author
author2 Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Zeljko
Branco, Luís
Pedrosa, Rui
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv IC-Online
dc.contributor.author.fl_str_mv Freitas, Rafaela
Martins, Alice
Silva, Joana
Alves, Celso
Pinteus, Susete
Alves, Joana
Teodoro, Fernando
Ribeiro, Helena Margarida
Gonçalves, Lídia
Petrovski, Zeljko
Branco, Luís
Pedrosa, Rui
dc.subject.por.fl_str_mv Fucus spiralis
Seaweeds
Antioxidant
Oxidative stress
Photoprotective
Anti-enzymatic
Anti-inflammatory
Skin microbiome
Dermo-cosmetics
topic Fucus spiralis
Seaweeds
Antioxidant
Oxidative stress
Photoprotective
Anti-enzymatic
Anti-inflammatory
Skin microbiome
Dermo-cosmetics
description Funding: This work was supported by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre, through Red2Discovery project (PTDC/MAR-BIO/6149/2014), co-financed by COMPETE (POCI-01-0145-FEDER-016791), through Oncologia de Precisão: Terapias e Tecnologias Inovadoras project (POINT4PAC) (SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405) and through CrossAtlantic project (PTDC/BIA-OUT/29250/2017), co-financed by COMPETE (POCI-01-0145-FEDER-029250). This work was also funded by the Integrated Programme of SR&TD Smart Valorization of Endogenous Marine Biological Resources Under a Changing Climate (Centro-01-0145-FEDER-000018), co-funded by Centro 2020 Programme, Portugal 2020, European Union, through the European Regional Development Fund.
publishDate 2020
dc.date.none.fl_str_mv 2020-08-28T11:11:19Z
2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.8/5113
url http://hdl.handle.net/10400.8/5113
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Freitas, R., Martins, A., Silva, J., Alves, C., Pinteus, S., Alves, J., Teodoro, F., Ribeiro, H. M., Gonçalves, L., Petrovski, Ž., Branco, L., & Pedrosa, R. (2020). Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications. Antioxidants (Basel, Switzerland), 9(7), 611. https://doi.org/10.3390/antiox9070611
2076-3921
10.3390/antiox9070611
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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