The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.22/16392 |
Resumo: | The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 °C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 µg/mL), whereby temperature of 150 °C was optimal. On the other hand, the extracts obtained at 115 °C showed highest cytotoxicity. Inhibition of α-amylase and α-glucosidase was the highest at 65 and 85 °C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 °C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts. |
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The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extractsAntioxidantsMatricariaPlant ExtractsPolyphenolsTandem Mass SpectrometryWaterUHPLC-HESI-MS/MSSubcritical water extractionChamomileDNA-based sensorBioactivityThe main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 °C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 µg/mL), whereby temperature of 150 °C was optimal. On the other hand, the extracts obtained at 115 °C showed highest cytotoxicity. Inhibition of α-amylase and α-glucosidase was the highest at 65 and 85 °C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 °C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts.The present work was carried out within the projects of the Serbian Ministry of Education, Science and Technological Development, Serbia, (Projects No. TR31013 and 172017). The authors are grateful to Dr Dušan Adamović, Institute of Field and Vegetable Crops, Bački Petrovac, Serbia, for his support in supplying plant material.REQUIMTE received financial support from Programme PT2020 (NORTE-07-0124-FEDER-000069 and NORTE-01-0145-FEDER-000011-RL1-QUALIFOOD) and from FCT (UID/QUI/50006/2013- POCI/01/0145/FEDER/007265). M. Fátima Barroso would like to thank also to FCT for the post-doc fellowship (SFRH/BPD/78845/2011).ElsevierRepositório Científico do Instituto Politécnico do PortoCvetanović, AleksandraŠvarc-Gajić, JaroslavaZeković, ZoranJerković, JelenaZengin, GokhanGašić, UrošTešić, ŽivoslavMašković, PavleSoares, CristinaBarroso, M. FátimaDelerue-Matos, CristinaĐurović, Saša2020-10-30T12:08:37Z2019-012019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/16392eng10.1016/j.foodchem.2018.07.154info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:02:46Zoai:recipp.ipp.pt:10400.22/16392Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:35:51.813838Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
title |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
spellingShingle |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts Cvetanović, Aleksandra Antioxidants Matricaria Plant Extracts Polyphenols Tandem Mass Spectrometry Water UHPLC-HESI-MS/MS Subcritical water extraction Chamomile DNA-based sensor Bioactivity |
title_short |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
title_full |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
title_fullStr |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
title_full_unstemmed |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
title_sort |
The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts |
author |
Cvetanović, Aleksandra |
author_facet |
Cvetanović, Aleksandra Švarc-Gajić, Jaroslava Zeković, Zoran Jerković, Jelena Zengin, Gokhan Gašić, Uroš Tešić, Živoslav Mašković, Pavle Soares, Cristina Barroso, M. Fátima Delerue-Matos, Cristina Đurović, Saša |
author_role |
author |
author2 |
Švarc-Gajić, Jaroslava Zeković, Zoran Jerković, Jelena Zengin, Gokhan Gašić, Uroš Tešić, Živoslav Mašković, Pavle Soares, Cristina Barroso, M. Fátima Delerue-Matos, Cristina Đurović, Saša |
author2_role |
author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Politécnico do Porto |
dc.contributor.author.fl_str_mv |
Cvetanović, Aleksandra Švarc-Gajić, Jaroslava Zeković, Zoran Jerković, Jelena Zengin, Gokhan Gašić, Uroš Tešić, Živoslav Mašković, Pavle Soares, Cristina Barroso, M. Fátima Delerue-Matos, Cristina Đurović, Saša |
dc.subject.por.fl_str_mv |
Antioxidants Matricaria Plant Extracts Polyphenols Tandem Mass Spectrometry Water UHPLC-HESI-MS/MS Subcritical water extraction Chamomile DNA-based sensor Bioactivity |
topic |
Antioxidants Matricaria Plant Extracts Polyphenols Tandem Mass Spectrometry Water UHPLC-HESI-MS/MS Subcritical water extraction Chamomile DNA-based sensor Bioactivity |
description |
The main goal of this research was to determine the relationship among chemical structure, bioactivity and temperature of chamomile during subcritical water extraction in isobaric conditions (45 bar) at seven different temperatures (65-210 °C). The influence of temperature on phenolic profiles was defined by UHPLC-HESI-MS/MS. The overall results indicate that the presence of conjugated double bonds, side chains, glucose moiety or ether moiety in molecules influence the efficiency of polyphenols' extraction in subcritical water. In terms of antioxidant activity, the extracts were the most active towards ABTS radicals (IC50 = 7.3-16.8 µg/mL), whereby temperature of 150 °C was optimal. On the other hand, the extracts obtained at 115 °C showed highest cytotoxicity. Inhibition of α-amylase and α-glucosidase was the highest at 65 and 85 °C, i.e. 0.51 and 4.13 mmolAE/g, respectively. Activity against tyrosinase was the highest at 210 °C (17.92 mgKAE/g). The data showed that different non-phenolic compounds may also participate in bio-activities of the extracts. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01 2019-01-01T00:00:00Z 2020-10-30T12:08:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.22/16392 |
url |
http://hdl.handle.net/10400.22/16392 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.foodchem.2018.07.154 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799131449871302656 |