Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve

Detalhes bibliográficos
Autor(a) principal: Viegas, Carla
Data de Publicação: 2021
Outros Autores: Twarużek, Magdalena, Dias, Marta, Almeida, Beatriz, Carolino, Elisabete, Soszczyńska, Ewelina, Viegas, Susana, Caetano, Liliana Aranha
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/13271
Resumo: Project EXPOsE. Project nº 23222 (02/SAICT/2016).
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spelling Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valveOccupational healthOccupational exposureCytotoxicityFiltering respiratory protective devicesMTT assayPassive samplingWaste sorting environmentRisk assessmentProject EXPOsEProject nº 23222 (02/SAICT/2016)Project Waste FRPDProject IPL/2018/WasteFRPD_ESTeSLUIDB/05608/2020UIDP/05608/2020Project EXPOsE. Project nº 23222 (02/SAICT/2016).Project Waste FRPD. Project IPL/2018/WasteFRPD_ESTeSL.UIDB/05608/2020. UIDP/05608/2020.Filtering respiratory protection devices (FRPD) is mandatory for workers to wear in the Portuguese waste-sorting industry. Previous results regarding microbial contamination found on the FRPD interior layer raised the question of whether microbial contamination from the exhalation valve would also have cytotoxicity effects. Since the FRPD exhalation valves are very close to workers’ nose and mouth, they represent a source of exposure to bioburden by inhalation. This study aimed to evaluate the cytotoxicity of the microbial contamination present in the FRPD exhalation valves. For this purpose, the cytotoxicity effects were determined through the MTT assay in two different cell lines (human A549 epithelial lung cells, and swine kidney cells) and compared with previous results obtained with FRPD interior layers. The contamination present in the FRPD exhalation valves presented some cytotoxicity on epithelial lung cells, suggesting the inhalation route as a potential route of exposure through the use of FRPD in the waste-sorting industry. Half-maximal (50%) inhibitory concentration (IC50) values were lower for the FRPD interior layer than exhalation valves in lung cells, with overall cytotoxicity lower in exhalation valves when compared to the interior layer (z = −4.455, p = 0.000). Higher bacterial counts in TSA were correlated with lower IC50 values, thus, higher cytotoxicity effect in lung cells. No statistically significant differences were detected among different workplaces.ElsevierRCIPLViegas, CarlaTwarużek, MagdalenaDias, MartaAlmeida, BeatrizCarolino, ElisabeteSoszczyńska, EwelinaViegas, SusanaCaetano, Liliana Aranha2021-05-03T18:22:17Z2024-05-03T00:00:00Z2021-102021-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/13271engViegas C, Twarużek M, Dias M, Almeida B, Carolino E, Viegas S, Caetano LA, et al. Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve. Environ Int. 2021;155:106603.10.1016/j.envint.2021.106603info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:07:44Zoai:repositorio.ipl.pt:10400.21/13271Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:21:15.240608Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
title Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
spellingShingle Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
Viegas, Carla
Occupational health
Occupational exposure
Cytotoxicity
Filtering respiratory protective devices
MTT assay
Passive sampling
Waste sorting environment
Risk assessment
Project EXPOsE
Project nº 23222 (02/SAICT/2016)
Project Waste FRPD
Project IPL/2018/WasteFRPD_ESTeSL
UIDB/05608/2020
UIDP/05608/2020
title_short Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
title_full Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
title_fullStr Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
title_full_unstemmed Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
title_sort Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
author Viegas, Carla
author_facet Viegas, Carla
Twarużek, Magdalena
Dias, Marta
Almeida, Beatriz
Carolino, Elisabete
Soszczyńska, Ewelina
Viegas, Susana
Caetano, Liliana Aranha
author_role author
author2 Twarużek, Magdalena
Dias, Marta
Almeida, Beatriz
Carolino, Elisabete
Soszczyńska, Ewelina
Viegas, Susana
Caetano, Liliana Aranha
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Viegas, Carla
Twarużek, Magdalena
Dias, Marta
Almeida, Beatriz
Carolino, Elisabete
Soszczyńska, Ewelina
Viegas, Susana
Caetano, Liliana Aranha
dc.subject.por.fl_str_mv Occupational health
Occupational exposure
Cytotoxicity
Filtering respiratory protective devices
MTT assay
Passive sampling
Waste sorting environment
Risk assessment
Project EXPOsE
Project nº 23222 (02/SAICT/2016)
Project Waste FRPD
Project IPL/2018/WasteFRPD_ESTeSL
UIDB/05608/2020
UIDP/05608/2020
topic Occupational health
Occupational exposure
Cytotoxicity
Filtering respiratory protective devices
MTT assay
Passive sampling
Waste sorting environment
Risk assessment
Project EXPOsE
Project nº 23222 (02/SAICT/2016)
Project Waste FRPD
Project IPL/2018/WasteFRPD_ESTeSL
UIDB/05608/2020
UIDP/05608/2020
description Project EXPOsE. Project nº 23222 (02/SAICT/2016).
publishDate 2021
dc.date.none.fl_str_mv 2021-05-03T18:22:17Z
2021-10
2021-10-01T00:00:00Z
2024-05-03T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/13271
url http://hdl.handle.net/10400.21/13271
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Viegas C, Twarużek M, Dias M, Almeida B, Carolino E, Viegas S, Caetano LA, et al. Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve. Environ Int. 2021;155:106603.
10.1016/j.envint.2021.106603
dc.rights.driver.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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