Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/13271 |
Resumo: | Project EXPOsE. Project nº 23222 (02/SAICT/2016). |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valveOccupational healthOccupational exposureCytotoxicityFiltering respiratory protective devicesMTT assayPassive samplingWaste sorting environmentRisk assessmentProject EXPOsEProject nº 23222 (02/SAICT/2016)Project Waste FRPDProject IPL/2018/WasteFRPD_ESTeSLUIDB/05608/2020UIDP/05608/2020Project EXPOsE. Project nº 23222 (02/SAICT/2016).Project Waste FRPD. Project IPL/2018/WasteFRPD_ESTeSL.UIDB/05608/2020. UIDP/05608/2020.Filtering respiratory protection devices (FRPD) is mandatory for workers to wear in the Portuguese waste-sorting industry. Previous results regarding microbial contamination found on the FRPD interior layer raised the question of whether microbial contamination from the exhalation valve would also have cytotoxicity effects. Since the FRPD exhalation valves are very close to workers’ nose and mouth, they represent a source of exposure to bioburden by inhalation. This study aimed to evaluate the cytotoxicity of the microbial contamination present in the FRPD exhalation valves. For this purpose, the cytotoxicity effects were determined through the MTT assay in two different cell lines (human A549 epithelial lung cells, and swine kidney cells) and compared with previous results obtained with FRPD interior layers. The contamination present in the FRPD exhalation valves presented some cytotoxicity on epithelial lung cells, suggesting the inhalation route as a potential route of exposure through the use of FRPD in the waste-sorting industry. Half-maximal (50%) inhibitory concentration (IC50) values were lower for the FRPD interior layer than exhalation valves in lung cells, with overall cytotoxicity lower in exhalation valves when compared to the interior layer (z = −4.455, p = 0.000). Higher bacterial counts in TSA were correlated with lower IC50 values, thus, higher cytotoxicity effect in lung cells. No statistically significant differences were detected among different workplaces.ElsevierRCIPLViegas, CarlaTwarużek, MagdalenaDias, MartaAlmeida, BeatrizCarolino, ElisabeteSoszczyńska, EwelinaViegas, SusanaCaetano, Liliana Aranha2021-05-03T18:22:17Z2024-05-03T00:00:00Z2021-102021-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/13271engViegas C, Twarużek M, Dias M, Almeida B, Carolino E, Viegas S, Caetano LA, et al. Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve. Environ Int. 2021;155:106603.10.1016/j.envint.2021.106603info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:07:44Zoai:repositorio.ipl.pt:10400.21/13271Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:21:15.240608Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
title |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
spellingShingle |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve Viegas, Carla Occupational health Occupational exposure Cytotoxicity Filtering respiratory protective devices MTT assay Passive sampling Waste sorting environment Risk assessment Project EXPOsE Project nº 23222 (02/SAICT/2016) Project Waste FRPD Project IPL/2018/WasteFRPD_ESTeSL UIDB/05608/2020 UIDP/05608/2020 |
title_short |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
title_full |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
title_fullStr |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
title_full_unstemmed |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
title_sort |
Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve |
author |
Viegas, Carla |
author_facet |
Viegas, Carla Twarużek, Magdalena Dias, Marta Almeida, Beatriz Carolino, Elisabete Soszczyńska, Ewelina Viegas, Susana Caetano, Liliana Aranha |
author_role |
author |
author2 |
Twarużek, Magdalena Dias, Marta Almeida, Beatriz Carolino, Elisabete Soszczyńska, Ewelina Viegas, Susana Caetano, Liliana Aranha |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Viegas, Carla Twarużek, Magdalena Dias, Marta Almeida, Beatriz Carolino, Elisabete Soszczyńska, Ewelina Viegas, Susana Caetano, Liliana Aranha |
dc.subject.por.fl_str_mv |
Occupational health Occupational exposure Cytotoxicity Filtering respiratory protective devices MTT assay Passive sampling Waste sorting environment Risk assessment Project EXPOsE Project nº 23222 (02/SAICT/2016) Project Waste FRPD Project IPL/2018/WasteFRPD_ESTeSL UIDB/05608/2020 UIDP/05608/2020 |
topic |
Occupational health Occupational exposure Cytotoxicity Filtering respiratory protective devices MTT assay Passive sampling Waste sorting environment Risk assessment Project EXPOsE Project nº 23222 (02/SAICT/2016) Project Waste FRPD Project IPL/2018/WasteFRPD_ESTeSL UIDB/05608/2020 UIDP/05608/2020 |
description |
Project EXPOsE. Project nº 23222 (02/SAICT/2016). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-03T18:22:17Z 2021-10 2021-10-01T00:00:00Z 2024-05-03T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/13271 |
url |
http://hdl.handle.net/10400.21/13271 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Viegas C, Twarużek M, Dias M, Almeida B, Carolino E, Viegas S, Caetano LA, et al. Cytotoxicity of filtering respiratory protective devices from the waste sorting industry: a comparative study between interior layer and exhalation valve. Environ Int. 2021;155:106603. 10.1016/j.envint.2021.106603 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799133483101061120 |