Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal

Detalhes bibliográficos
Autor(a) principal: Miguel, Maria da Graça
Data de Publicação: 2015
Outros Autores: Gago, Custódia, Antunes, Maria Dulce, Megías, Cristina, Cortés-Giraldo, Isabel, Vioque, Javier, Lima, Ana Sofia, Figueiredo, Ana Cristina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/16135
Resumo: The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS < sup > ·+ < /sup > and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
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spelling Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in PortugalThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS < sup > ·+ < /sup > and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.This study was partially funded by Fundac¸˜ao para a Ciˆencia e Tecnologia (FCT), under Pest-OE/EQB/LA0023/2011 and UID/AMB/50017/2013.This study was partially funded by Fundac¸˜ao para a Ciˆencia e Tecnologia (FCT), under Pest-OE/EQB/LA0023/2011 and UID/AMB/50017/2013.Biblioteca Digital do IPBMiguel, Maria da GraçaGago, CustódiaAntunes, Maria DulceMegías, CristinaCortés-Giraldo, IsabelVioque, JavierLima, Ana SofiaFigueiredo, Ana Cristina2018-01-19T10:00:00Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/16135engMiguel, Maria Graça; Gago, Custódia; Antunes, Maria Dulce; Megías, Cristina; Cortés-Giraldo, Isabel; Vioque, Javier; Lima, A. Sofia; Figueiredo, A. Cristina (2015). Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal. Evidence-based Complementary and Alternative Medicine. ISSN 1741-427X. 2015, p.1741-427X10.1155/2015/851721info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:37:13Zoai:bibliotecadigital.ipb.pt:10198/16135Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:05:25.203103Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
spellingShingle Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
Miguel, Maria da Graça
title_short Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_full Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_fullStr Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_full_unstemmed Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
title_sort Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal
author Miguel, Maria da Graça
author_facet Miguel, Maria da Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, Ana Sofia
Figueiredo, Ana Cristina
author_role author
author2 Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, Ana Sofia
Figueiredo, Ana Cristina
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Miguel, Maria da Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Lima, Ana Sofia
Figueiredo, Ana Cristina
description The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS < sup > ·+ < /sup > and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2018-01-19T10:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/16135
url http://hdl.handle.net/10198/16135
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Miguel, Maria Graça; Gago, Custódia; Antunes, Maria Dulce; Megías, Cristina; Cortés-Giraldo, Isabel; Vioque, Javier; Lima, A. Sofia; Figueiredo, A. Cristina (2015). Antioxidant and Antiproliferative Activities of the Essential Oils from Thymbra capitata and Thymus Species Grown in Portugal. Evidence-based Complementary and Alternative Medicine. ISSN 1741-427X. 2015, p.
1741-427X
10.1155/2015/851721
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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