Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal

Detalhes bibliográficos
Autor(a) principal: Miguel, Maria
Data de Publicação: 2015
Outros Autores: Gago, Custódia, Antunes, Maria Dulce, Megias, Cristina, Cortes-Giraldo, Isabel, Vioque, Javier, Sofia Lima, A., Cristina Figueiredo, A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/12022
Resumo: The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
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spelling Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in PortugalAssayThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.Fundacao para a Ciencia e Tecnologia (FCT) [Pest-OE/EQB/LA0023/2011]Hindawi Publishing CorporationSapientiaMiguel, MariaGago, CustódiaAntunes, Maria DulceMegias, CristinaCortes-Giraldo, IsabelVioque, JavierSofia Lima, A.Cristina Figueiredo, A.2018-12-07T14:58:26Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/12022eng1741-427X10.1155/2015/851721info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:23:57Zoai:sapientia.ualg.pt:10400.1/12022Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:03:26.614724Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
title Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
spellingShingle Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
Miguel, Maria
Assay
title_short Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
title_full Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
title_fullStr Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
title_full_unstemmed Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
title_sort Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
author Miguel, Maria
author_facet Miguel, Maria
Gago, Custódia
Antunes, Maria Dulce
Megias, Cristina
Cortes-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
author_role author
author2 Gago, Custódia
Antunes, Maria Dulce
Megias, Cristina
Cortes-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Miguel, Maria
Gago, Custódia
Antunes, Maria Dulce
Megias, Cristina
Cortes-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
dc.subject.por.fl_str_mv Assay
topic Assay
description The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2018-12-07T14:58:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/12022
url http://hdl.handle.net/10400.1/12022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1741-427X
10.1155/2015/851721
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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