Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal

Detalhes bibliográficos
Autor(a) principal: Miguel, Maria Graça
Data de Publicação: 2015
Outros Autores: Gago, Custódia, Antunes, Maria Dulce, Megías, Cristina, Cortés-Giraldo, Isabel, Vioque, Javier, Sofia Lima, A., Cristina Figueiredo, A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/17993
Resumo: The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS•+ and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
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spelling Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in PortugalThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS•+ and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.Hindawi Publishing Corporation2017-06-29T10:37:56Z2015-01-01T00:00:00Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/17993eng1741-427X10.1155/2015/851721Miguel, Maria GraçaGago, CustódiaAntunes, Maria DulceMegías, CristinaCortés-Giraldo, IsabelVioque, JavierSofia Lima, A.Cristina Figueiredo, A.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:31:45Zoai:ria.ua.pt:10773/17993Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:51:59.360545Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
title Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
spellingShingle Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
Miguel, Maria Graça
title_short Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
title_full Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
title_fullStr Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
title_full_unstemmed Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
title_sort Antioxidant and antiproliferative activities of the essential oils from thymbra capitata and thymus species grown in Portugal
author Miguel, Maria Graça
author_facet Miguel, Maria Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
author_role author
author2 Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Miguel, Maria Graça
Gago, Custódia
Antunes, Maria Dulce
Megías, Cristina
Cortés-Giraldo, Isabel
Vioque, Javier
Sofia Lima, A.
Cristina Figueiredo, A.
description The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, α-terpineol, and γ-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS•+ and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01T00:00:00Z
2015
2017-06-29T10:37:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/17993
url http://hdl.handle.net/10773/17993
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1741-427X
10.1155/2015/851721
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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