Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals

Detalhes bibliográficos
Autor(a) principal: Viegas, Susana
Data de Publicação: 2014
Outros Autores: Pádua, Mário, Gomes, Mário
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/3216
Resumo: During the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals.
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spelling Surfaces contamination with 5-Fluorouracil in two Portuguese hospitalsOccupational exposureCytostatic drugsDermal absoptionWipe samplingDuring the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals.RCIPLViegas, SusanaPádua, MárioGomes, Mário2014-02-19T13:59:38Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/3216engViegas S, Pádua M, Gomes M. Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals. In Arezes PM, Batista JS, Barroso MP, Carneiro P, Cordeiro P, Costa N, et al, editors. SHO2014 – International Symposium on Occupational Safety and Hygiene: proceedings book. p. 468-70.978-989-98203-2-6info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:43:33Zoai:repositorio.ipl.pt:10400.21/3216Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:12:51.427240Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
title Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
spellingShingle Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
Viegas, Susana
Occupational exposure
Cytostatic drugs
Dermal absoption
Wipe sampling
title_short Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
title_full Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
title_fullStr Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
title_full_unstemmed Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
title_sort Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
author Viegas, Susana
author_facet Viegas, Susana
Pádua, Mário
Gomes, Mário
author_role author
author2 Pádua, Mário
Gomes, Mário
author2_role author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Viegas, Susana
Pádua, Mário
Gomes, Mário
dc.subject.por.fl_str_mv Occupational exposure
Cytostatic drugs
Dermal absoption
Wipe sampling
topic Occupational exposure
Cytostatic drugs
Dermal absoption
Wipe sampling
description During the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals.
publishDate 2014
dc.date.none.fl_str_mv 2014-02-19T13:59:38Z
2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/3216
url http://hdl.handle.net/10400.21/3216
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Viegas S, Pádua M, Gomes M. Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals. In Arezes PM, Batista JS, Barroso MP, Carneiro P, Cordeiro P, Costa N, et al, editors. SHO2014 – International Symposium on Occupational Safety and Hygiene: proceedings book. p. 468-70.
978-989-98203-2-6
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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