Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.21/3216 |
Resumo: | During the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals. |
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Surfaces contamination with 5-Fluorouracil in two Portuguese hospitalsOccupational exposureCytostatic drugsDermal absoptionWipe samplingDuring the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals.RCIPLViegas, SusanaPádua, MárioGomes, Mário2014-02-19T13:59:38Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/3216engViegas S, Pádua M, Gomes M. Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals. In Arezes PM, Batista JS, Barroso MP, Carneiro P, Cordeiro P, Costa N, et al, editors. SHO2014 – International Symposium on Occupational Safety and Hygiene: proceedings book. p. 468-70.978-989-98203-2-6info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:43:33Zoai:repositorio.ipl.pt:10400.21/3216Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:12:51.427240Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
title |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
spellingShingle |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals Viegas, Susana Occupational exposure Cytostatic drugs Dermal absoption Wipe sampling |
title_short |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
title_full |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
title_fullStr |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
title_full_unstemmed |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
title_sort |
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals |
author |
Viegas, Susana |
author_facet |
Viegas, Susana Pádua, Mário Gomes, Mário |
author_role |
author |
author2 |
Pádua, Mário Gomes, Mário |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
RCIPL |
dc.contributor.author.fl_str_mv |
Viegas, Susana Pádua, Mário Gomes, Mário |
dc.subject.por.fl_str_mv |
Occupational exposure Cytostatic drugs Dermal absoption Wipe sampling |
topic |
Occupational exposure Cytostatic drugs Dermal absoption Wipe sampling |
description |
During the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects. Consequently, rigorous guidelines for the safe handling of cancer chemotherapeutic agents were devised and the handling facilities in hospitals were extensively improved. However, recent studies developed in European countries revealed detectable amounts of several drugs in surface wipe samples. Dermal absorption after contact with contaminated surfaces can play an important role in exposure to antineoplastic drugs. Therefore, the existence of contamination in workplace surfaces implies an increased risk of exposure for health care workers. Since there is no recent report in Portugal, regarding the occupational exposure to antineoplastic drugs, a study was developed aiming to determine the 5-fluorouracil (5-FU) contamination on work surfaces of two Portuguese hospitals. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-02-19T13:59:38Z 2014 2014-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.21/3216 |
url |
http://hdl.handle.net/10400.21/3216 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Viegas S, Pádua M, Gomes M. Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals. In Arezes PM, Batista JS, Barroso MP, Carneiro P, Cordeiro P, Costa N, et al, editors. SHO2014 – International Symposium on Occupational Safety and Hygiene: proceedings book. p. 468-70. 978-989-98203-2-6 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133384452079616 |