Sweet Syndrome and HIV Infection: What We Can Interpret?

• Autor(a) principal: Coutinho, Pedro Paulo
• Data de Publicação: 2018
• Outros Autores: Araújo de Moura, Amanda, de Castro e Souza, Bruno, Real António, Bruno Vianei, Rocha de Alencar, Raquel Rodrigues Ferreira, Francesconi do Valle, Fábio
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.29021/spdv.76.4.931
• topic: Antiretroviral Therapy; Highly Active; HIV Infections; Immune Reconstitution Inflammatory Syndrome; Sweet Syndrome; Infecções por VIH; Síndrome Inflamatória da Reconstituição Imune; Síndrome de Sweet; Terapia Antirretroviral de Alta Atividade.

Sweet's syndrome is a neutrophilic dermatosis whose etiopathogenesis is not yet fully known. Histopathology of cutaneous lesions shows an infiltrate with mature neutrophils diffusely distributed in the papillary dermis. The diagnosis is made through clinical, laboratory and histopathological criteria. Association of Sweet syndrome and HIV infection is scarcely related in the literature, having been reported with the use of abacavir, opportunistic infections and vaccination. The explicit evidence for the association is considering Sweet's syndrome as a manifestation of immune reconstitution syndrome, which occurs in 10% to 45% of HIV-infected individuals at the start of antiretroviral therapy. The present report describes the case of a patient HIV-positive for 4 years, who maintained antiretroviral therapy irregularity and, after regularizing the use of antiretrovirals, developed Sweet syndrome.