Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains

Detalhes bibliográficos
Autor(a) principal: Garcia-Gonzalo, Francesc R.
Data de Publicação: 2021
Outros Autores: Soares, Helena, Lopes, Susana S., Inoue, Takanari
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/13997
Resumo: FCT_UIDB/00100/2020. FCT_UIDP/00100/2020.
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spelling Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domainsPrimary ciliaCiliopathiesCiliogenesisMotile/immotile ciliaCilia signalingFCT_UIDB/00100/2020FCT_UIDP/00100/2020FCT_UIDB/00100/2020. FCT_UIDP/00100/2020.Cilia are fascinating microtubule-based compartments that project from the cell surface. Cilia can be functionally classified as motile (generating cell movement or fluid flow) or immotile (primary cilia, which transduce mechanical, optical, or chemical signals through a variety of pathways, such as Hedgehog, GPCR, Notch, Wnt, Hippo, mTOR, PDGFR, or TGFβ. Structurally, cilia are composed of a microtubule shaft (axoneme) that elongates from a membrane-anchored centriole (basal body) and are covered by a highly specialized ciliary membrane. Most human cell types form cilia, dysfunction of which leads to diseases such as cancer and ciliopathies, a diverse group of disorders affecting eyes, kidneys, and brain, among other organs. This Research Topic spans multiple aspects of motile and primary cilia composition and function, ciliary mechanisms, and the physiopathological roles of cilia in different tissues. Here we describe some of the highlights.Frontiers MediaRCIPLGarcia-Gonzalo, Francesc R.Soares, HelenaLopes, Susana S.Inoue, Takanari2021-11-15T11:06:52Z2021-102021-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/13997engGarcía-Gonzalo FR, Soares H, Lopes SS, Inoue T. Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains. Front Cell Dev Biol. 2021;9:777758.10.3389/fcell.2021.777758info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T10:09:35Zoai:repositorio.ipl.pt:10400.21/13997Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:21:53.042526Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
title Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
spellingShingle Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
Garcia-Gonzalo, Francesc R.
Primary cilia
Ciliopathies
Ciliogenesis
Motile/immotile cilia
Cilia signaling
FCT_UIDB/00100/2020
FCT_UIDP/00100/2020
title_short Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
title_full Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
title_fullStr Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
title_full_unstemmed Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
title_sort Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains
author Garcia-Gonzalo, Francesc R.
author_facet Garcia-Gonzalo, Francesc R.
Soares, Helena
Lopes, Susana S.
Inoue, Takanari
author_role author
author2 Soares, Helena
Lopes, Susana S.
Inoue, Takanari
author2_role author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Garcia-Gonzalo, Francesc R.
Soares, Helena
Lopes, Susana S.
Inoue, Takanari
dc.subject.por.fl_str_mv Primary cilia
Ciliopathies
Ciliogenesis
Motile/immotile cilia
Cilia signaling
FCT_UIDB/00100/2020
FCT_UIDP/00100/2020
topic Primary cilia
Ciliopathies
Ciliogenesis
Motile/immotile cilia
Cilia signaling
FCT_UIDB/00100/2020
FCT_UIDP/00100/2020
description FCT_UIDB/00100/2020. FCT_UIDP/00100/2020.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-15T11:06:52Z
2021-10
2021-10-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/13997
url http://hdl.handle.net/10400.21/13997
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv García-Gonzalo FR, Soares H, Lopes SS, Inoue T. Editorial: The cytoskeleton and cellular compartmentation: Cilia as specialized cellular domains. Front Cell Dev Biol. 2021;9:777758.
10.3389/fcell.2021.777758
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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