Blood plasma derivatives for tissue engineering and regenerative medicine therapied

Detalhes bibliográficos
Autor(a) principal: Santos, Sara Catarina Nunes da Silva
Data de Publicação: 2018
Outros Autores: Sigurjonsson, Ólafur Eysteinn, Custódio, Catarina de Almeida, Mano, João Filipe Colardelle da Luz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/25662
Resumo: Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions.
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spelling Blood plasma derivatives for tissue engineering and regenerative medicine therapiedPersonalized medicinePlatelet lysatesPlatelet-rich plasmaPlateletsPlatelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions.Mary Ann Liebert2019-03-27T16:54:56Z2018-12-01T00:00:00Z2018-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://hdl.handle.net/10773/25662eng1937-336810.1089/ten.TEB.2018.0008Santos, Sara Catarina Nunes da SilvaSigurjonsson, Ólafur EysteinnCustódio, Catarina de AlmeidaMano, João Filipe Colardelle da Luzinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:49:44Zoai:ria.ua.pt:10773/25662Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:58:50.262967Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Blood plasma derivatives for tissue engineering and regenerative medicine therapied
title Blood plasma derivatives for tissue engineering and regenerative medicine therapied
spellingShingle Blood plasma derivatives for tissue engineering and regenerative medicine therapied
Santos, Sara Catarina Nunes da Silva
Personalized medicine
Platelet lysates
Platelet-rich plasma
Platelets
title_short Blood plasma derivatives for tissue engineering and regenerative medicine therapied
title_full Blood plasma derivatives for tissue engineering and regenerative medicine therapied
title_fullStr Blood plasma derivatives for tissue engineering and regenerative medicine therapied
title_full_unstemmed Blood plasma derivatives for tissue engineering and regenerative medicine therapied
title_sort Blood plasma derivatives for tissue engineering and regenerative medicine therapied
author Santos, Sara Catarina Nunes da Silva
author_facet Santos, Sara Catarina Nunes da Silva
Sigurjonsson, Ólafur Eysteinn
Custódio, Catarina de Almeida
Mano, João Filipe Colardelle da Luz
author_role author
author2 Sigurjonsson, Ólafur Eysteinn
Custódio, Catarina de Almeida
Mano, João Filipe Colardelle da Luz
author2_role author
author
author
dc.contributor.author.fl_str_mv Santos, Sara Catarina Nunes da Silva
Sigurjonsson, Ólafur Eysteinn
Custódio, Catarina de Almeida
Mano, João Filipe Colardelle da Luz
dc.subject.por.fl_str_mv Personalized medicine
Platelet lysates
Platelet-rich plasma
Platelets
topic Personalized medicine
Platelet lysates
Platelet-rich plasma
Platelets
description Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-01T00:00:00Z
2018-12
2019-03-27T16:54:56Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/25662
url http://hdl.handle.net/10773/25662
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1937-3368
10.1089/ten.TEB.2018.0008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/vnd.openxmlformats-officedocument.wordprocessingml.document
dc.publisher.none.fl_str_mv Mary Ann Liebert
publisher.none.fl_str_mv Mary Ann Liebert
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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