Blood plasma derivatives for tissue engineering and regenerative medicine therapied
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/25662 |
Resumo: | Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions. |
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Blood plasma derivatives for tissue engineering and regenerative medicine therapiedPersonalized medicinePlatelet lysatesPlatelet-rich plasmaPlateletsPlatelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions.Mary Ann Liebert2019-03-27T16:54:56Z2018-12-01T00:00:00Z2018-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/vnd.openxmlformats-officedocument.wordprocessingml.documenthttp://hdl.handle.net/10773/25662eng1937-336810.1089/ten.TEB.2018.0008Santos, Sara Catarina Nunes da SilvaSigurjonsson, Ólafur EysteinnCustódio, Catarina de AlmeidaMano, João Filipe Colardelle da Luzinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:49:44Zoai:ria.ua.pt:10773/25662Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:58:50.262967Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
title |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
spellingShingle |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied Santos, Sara Catarina Nunes da Silva Personalized medicine Platelet lysates Platelet-rich plasma Platelets |
title_short |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
title_full |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
title_fullStr |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
title_full_unstemmed |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
title_sort |
Blood plasma derivatives for tissue engineering and regenerative medicine therapied |
author |
Santos, Sara Catarina Nunes da Silva |
author_facet |
Santos, Sara Catarina Nunes da Silva Sigurjonsson, Ólafur Eysteinn Custódio, Catarina de Almeida Mano, João Filipe Colardelle da Luz |
author_role |
author |
author2 |
Sigurjonsson, Ólafur Eysteinn Custódio, Catarina de Almeida Mano, João Filipe Colardelle da Luz |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Santos, Sara Catarina Nunes da Silva Sigurjonsson, Ólafur Eysteinn Custódio, Catarina de Almeida Mano, João Filipe Colardelle da Luz |
dc.subject.por.fl_str_mv |
Personalized medicine Platelet lysates Platelet-rich plasma Platelets |
topic |
Personalized medicine Platelet lysates Platelet-rich plasma Platelets |
description |
Platelet-rich plasma (PRP) and its derivatives have been investigated and applied in regenerative medicine. The use of PRP as a supplement of cell culture media has consistently shown to potentiate stem cell proliferation, migration, and differentiation. In addition, the clinical utility of PRP is supported by evidence that PRP contains high concentrations of growth factors (GFs) and proteins which contribute to the regenerative process. PRP based therapies are cost effective and also benefit from the accessibility and safety of using the patient's own GFs. In the last years, a great development has been witnessed on PRP based biomaterials, with both structural and functional purposes. In this study we overview the most relevant PRP applications encompassing PRP based materials for tissue engineering and regenerative medicine. This review also summarizes the challenges in the fields of tissue engineering and regenerative medicine and provides a perspective on future directions. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01T00:00:00Z 2018-12 2019-03-27T16:54:56Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/25662 |
url |
http://hdl.handle.net/10773/25662 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1937-3368 10.1089/ten.TEB.2018.0008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/vnd.openxmlformats-officedocument.wordprocessingml.document |
dc.publisher.none.fl_str_mv |
Mary Ann Liebert |
publisher.none.fl_str_mv |
Mary Ann Liebert |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
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1799137642571366400 |