The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/39327 |
Resumo: | Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during viral infections. By modulating the modification landscape of viral and host RNAs, viruses enhance their propagation and elude host surveillance mechanisms. Here, we discuss how specific RNA modifications, in either host or viral RNA molecules, impact the virus-life cycle and host antiviral responses, highlighting the potential of targeting the RNA epitranscriptome for novel antiviral therapies. |
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The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infectionsRNA epitranscriptomeVirus-host cell interactionsHost antiviral responseCoding-RNAsNon-coding RNAsEmerging evidence highlights the multifaceted roles of the RNA epitranscriptome during viral infections. By modulating the modification landscape of viral and host RNAs, viruses enhance their propagation and elude host surveillance mechanisms. Here, we discuss how specific RNA modifications, in either host or viral RNA molecules, impact the virus-life cycle and host antiviral responses, highlighting the potential of targeting the RNA epitranscriptome for novel antiviral therapies.Frontiers Media2023-09-07T11:13:53Z2023-08-01T00:00:00Z2023-08-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/39327eng10.3389/fgene.2023.1245683Ribeiro, Diana RobertaNunes, AlexandreRibeiro, DanielaSoares, Ana Raquelinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T12:16:43Zoai:ria.ua.pt:10773/39327Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:09:30.224830Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
title |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
spellingShingle |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections Ribeiro, Diana Roberta RNA epitranscriptome Virus-host cell interactions Host antiviral response Coding-RNAs Non-coding RNAs |
title_short |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
title_full |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
title_fullStr |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
title_full_unstemmed |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
title_sort |
The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections |
author |
Ribeiro, Diana Roberta |
author_facet |
Ribeiro, Diana Roberta Nunes, Alexandre Ribeiro, Daniela Soares, Ana Raquel |
author_role |
author |
author2 |
Nunes, Alexandre Ribeiro, Daniela Soares, Ana Raquel |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, Diana Roberta Nunes, Alexandre Ribeiro, Daniela Soares, Ana Raquel |
dc.subject.por.fl_str_mv |
RNA epitranscriptome Virus-host cell interactions Host antiviral response Coding-RNAs Non-coding RNAs |
topic |
RNA epitranscriptome Virus-host cell interactions Host antiviral response Coding-RNAs Non-coding RNAs |
description |
Emerging evidence highlights the multifaceted roles of the RNA epitranscriptome during viral infections. By modulating the modification landscape of viral and host RNAs, viruses enhance their propagation and elude host surveillance mechanisms. Here, we discuss how specific RNA modifications, in either host or viral RNA molecules, impact the virus-life cycle and host antiviral responses, highlighting the potential of targeting the RNA epitranscriptome for novel antiviral therapies. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-07T11:13:53Z 2023-08-01T00:00:00Z 2023-08-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/39327 |
url |
http://hdl.handle.net/10773/39327 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.3389/fgene.2023.1245683 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Frontiers Media |
publisher.none.fl_str_mv |
Frontiers Media |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799137745533140992 |