Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/12022 |
Resumo: | The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells. |
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Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in PortugalAssayThe antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells.Fundacao para a Ciencia e Tecnologia (FCT) [Pest-OE/EQB/LA0023/2011]Hindawi Publishing CorporationSapientiaMiguel, MariaGago, CustódiaAntunes, Maria DulceMegias, CristinaCortes-Giraldo, IsabelVioque, JavierSofia Lima, A.Cristina Figueiredo, A.2018-12-07T14:58:26Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/12022eng1741-427X10.1155/2015/851721info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:23:57Zoai:sapientia.ualg.pt:10400.1/12022Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:03:26.614724Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
title |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
spellingShingle |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal Miguel, Maria Assay |
title_short |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
title_full |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
title_fullStr |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
title_full_unstemmed |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
title_sort |
Antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus Species grown in Portugal |
author |
Miguel, Maria |
author_facet |
Miguel, Maria Gago, Custódia Antunes, Maria Dulce Megias, Cristina Cortes-Giraldo, Isabel Vioque, Javier Sofia Lima, A. Cristina Figueiredo, A. |
author_role |
author |
author2 |
Gago, Custódia Antunes, Maria Dulce Megias, Cristina Cortes-Giraldo, Isabel Vioque, Javier Sofia Lima, A. Cristina Figueiredo, A. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Miguel, Maria Gago, Custódia Antunes, Maria Dulce Megias, Cristina Cortes-Giraldo, Isabel Vioque, Javier Sofia Lima, A. Cristina Figueiredo, A. |
dc.subject.por.fl_str_mv |
Assay |
topic |
Assay |
description |
The antioxidant and antiproliferative activities of the essential oils from Thymbra capitata and Thymus species grown in Portugal were evaluated. Thymbra and Thymus essential oils were grouped into two clusters: Cluster I in which carvacrol, thymol, p-cymene, alpha-terpineol, and gamma-terpinene dominated and Cluster II in which thymol and carvacrol were absent and the main constituent was linalool. The ability for scavenging ABTS(center dot+) and peroxyl free radicals as well as for preventing the growth of THP-1 leukemia cells was better in essential oils with the highest contents of thymol and carvacrol. These results show the importance of these two terpene-phenolic compounds as antioxidants and cytotoxic agents against THP-1 cells. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015 2015-01-01T00:00:00Z 2018-12-07T14:58:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/12022 |
url |
http://hdl.handle.net/10400.1/12022 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1741-427X 10.1155/2015/851721 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133268888518656 |