Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.7/216 http://dx.doi.org/10.1186/1475-2875-4-5 |
Resumo: | The observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
spelling |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infectionImmunity, Innate/immunologyImmunoglobulin G/bloodImmunoglobulin G/immunologyMalaria, Falciparum/epidemiologyMalaria, Falciparum/immunologyMalaria, Vivax/epidemiologyMalaria, Vivax/immunologyEscherichia coli Proteins/immunologyThe observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction.Biomed CentralARCAFesel, C.Goulart, L.F.Neto, A.S.Coelho, A.Fontes, C.J.F.Braga, E.M.Vaz, N.M.2011-05-19T09:14:28Z2005-012005-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/216http://dx.doi.org/10.1186/1475-2875-4-5eng1475-2875info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-11-21T14:20:00Zoai:arca.igc.gulbenkian.pt:10400.7/216Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-21T14:20Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
title |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
spellingShingle |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection Fesel, C. Immunity, Innate/immunology Immunoglobulin G/blood Immunoglobulin G/immunology Malaria, Falciparum/epidemiology Malaria, Falciparum/immunology Malaria, Vivax/epidemiology Malaria, Vivax/immunology Escherichia coli Proteins/immunology |
title_short |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
title_full |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
title_fullStr |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
title_full_unstemmed |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
title_sort |
Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection |
author |
Fesel, C. |
author_facet |
Fesel, C. Goulart, L.F. Neto, A.S. Coelho, A. Fontes, C.J.F. Braga, E.M. Vaz, N.M. |
author_role |
author |
author2 |
Goulart, L.F. Neto, A.S. Coelho, A. Fontes, C.J.F. Braga, E.M. Vaz, N.M. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
ARCA |
dc.contributor.author.fl_str_mv |
Fesel, C. Goulart, L.F. Neto, A.S. Coelho, A. Fontes, C.J.F. Braga, E.M. Vaz, N.M. |
dc.subject.por.fl_str_mv |
Immunity, Innate/immunology Immunoglobulin G/blood Immunoglobulin G/immunology Malaria, Falciparum/epidemiology Malaria, Falciparum/immunology Malaria, Vivax/epidemiology Malaria, Vivax/immunology Escherichia coli Proteins/immunology |
topic |
Immunity, Innate/immunology Immunoglobulin G/blood Immunoglobulin G/immunology Malaria, Falciparum/epidemiology Malaria, Falciparum/immunology Malaria, Vivax/epidemiology Malaria, Vivax/immunology Escherichia coli Proteins/immunology |
description |
The observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-01 2005-01-01T00:00:00Z 2011-05-19T09:14:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.7/216 http://dx.doi.org/10.1186/1475-2875-4-5 |
url |
http://hdl.handle.net/10400.7/216 http://dx.doi.org/10.1186/1475-2875-4-5 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1475-2875 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central |
publisher.none.fl_str_mv |
Biomed Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
_version_ |
1817549559852695552 |