Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection

Detalhes bibliográficos
Autor(a) principal: Fesel, C.
Data de Publicação: 2005
Outros Autores: Goulart, L.F., Neto, A.S., Coelho, A., Fontes, C.J.F., Braga, E.M., Vaz, N.M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/216
Resumo: The observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction.
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spelling Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infectionImmunity, Innate/immunologyImmunoglobulin G/bloodImmunoglobulin G/immunologyMalaria, Falciparum/epidemiologyMalaria, Falciparum/immunologyMalaria, Vivax/epidemiologyMalaria, Vivax/immunologyEscherichia coli Proteins/immunologyThe observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction.Biomed CentralARCAFesel, C.Goulart, L.F.Neto, A.S.Coelho, A.Fontes, C.J.F.Braga, E.M.Vaz, N.M.2011-05-19T09:14:28Z2005-012005-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/216engFesel, C., L. F. Goulart, A. S. Neto, A. Coelho, C. J. F. Fontes, E. M. Braga and N. M. Vaz (2005). "Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection." Malaria Journal 4:51475-2875info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:34:42Zoai:arca.igc.gulbenkian.pt:10400.7/216Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:37.271618Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
title Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
spellingShingle Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
Fesel, C.
Immunity, Innate/immunology
Immunoglobulin G/blood
Immunoglobulin G/immunology
Malaria, Falciparum/epidemiology
Malaria, Falciparum/immunology
Malaria, Vivax/epidemiology
Malaria, Vivax/immunology
Escherichia coli Proteins/immunology
title_short Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
title_full Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
title_fullStr Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
title_full_unstemmed Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
title_sort Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection
author Fesel, C.
author_facet Fesel, C.
Goulart, L.F.
Neto, A.S.
Coelho, A.
Fontes, C.J.F.
Braga, E.M.
Vaz, N.M.
author_role author
author2 Goulart, L.F.
Neto, A.S.
Coelho, A.
Fontes, C.J.F.
Braga, E.M.
Vaz, N.M.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv Fesel, C.
Goulart, L.F.
Neto, A.S.
Coelho, A.
Fontes, C.J.F.
Braga, E.M.
Vaz, N.M.
dc.subject.por.fl_str_mv Immunity, Innate/immunology
Immunoglobulin G/blood
Immunoglobulin G/immunology
Malaria, Falciparum/epidemiology
Malaria, Falciparum/immunology
Malaria, Vivax/epidemiology
Malaria, Vivax/immunology
Escherichia coli Proteins/immunology
topic Immunity, Innate/immunology
Immunoglobulin G/blood
Immunoglobulin G/immunology
Malaria, Falciparum/epidemiology
Malaria, Falciparum/immunology
Malaria, Vivax/epidemiology
Malaria, Vivax/immunology
Escherichia coli Proteins/immunology
description The observed difference in polyclonal antibody production seems related to intrinsic activation states of infected individuals, rather than to parasite-antigen specific immune responses. However, it appears influenced by preceding stimuli. This supports the idea that acquired clinical immunity may not exclusively depend on antigen-specific responses, but also on the individual polyclonal reaction.
publishDate 2005
dc.date.none.fl_str_mv 2005-01
2005-01-01T00:00:00Z
2011-05-19T09:14:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/216
url http://hdl.handle.net/10400.7/216
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fesel, C., L. F. Goulart, A. S. Neto, A. Coelho, C. J. F. Fontes, E. M. Braga and N. M. Vaz (2005). "Increased polyclonal immunoglobulin reactivity toward human and bacterial proteins is associated with clinical protection in human Plasmodium infection." Malaria Journal 4:5
1475-2875
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Biomed Central
publisher.none.fl_str_mv Biomed Central
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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