Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/104651 https://doi.org/10.3390/ijerph18094841 |
Resumo: | Youth obesity is a strong predictor of adult obesity, which has well-known negative health consequences. Thus, addressing adult obesity requires tackling youth obesity. MED4Youth's main objective is to strengthen the link between the Mediterranean Diet (MD) and the health benefits against youth obesity and associated cardiovascular disease (CVD) risk factors, identifying positive effects exerted by an MD including sourdough bread and healthy products from the Mediterranean basis (chickpeas/hummus, nuts, and pomegranate juice). For this purpose, a multicenter randomized controlled trial in which an MD-based intervention will be compared to a traditional low-fat diet intervention will be carried out with 240 overweight and obese adolescents (13-17 years) from Spain, Portugal, and Italy. Both interventions will be combined with an educational web-application addressed to engage the adolescents through a learning-through-playing approach, using both educational materials and games. To assess the interventions, adherence to the MD, dietary records, physical activity, food frequency, sociodemographic, and quality of life questionnaires as well as classical anthropometric and biochemical parameters will be evaluated. Furthermore, an omics approach will be performed to elucidate whether the interventions can shape the gut microbiota and gut-derived metabolites to gain knowledge on the mechanisms through which the MD can exert its beneficial effects. |
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Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Studyadolescentsyouth obesityMediterranean dietcardiovascular risk factorseducational approachhealthy food productsomicsgut microbiotaAdolescentDiet, Fat-RestrictedHumansItalyMulticenter Studies as TopicObesityPortugalQuality of LifeRandomized Controlled Trials as TopicSpainDiet, MediterraneanYouth obesity is a strong predictor of adult obesity, which has well-known negative health consequences. Thus, addressing adult obesity requires tackling youth obesity. MED4Youth's main objective is to strengthen the link between the Mediterranean Diet (MD) and the health benefits against youth obesity and associated cardiovascular disease (CVD) risk factors, identifying positive effects exerted by an MD including sourdough bread and healthy products from the Mediterranean basis (chickpeas/hummus, nuts, and pomegranate juice). For this purpose, a multicenter randomized controlled trial in which an MD-based intervention will be compared to a traditional low-fat diet intervention will be carried out with 240 overweight and obese adolescents (13-17 years) from Spain, Portugal, and Italy. Both interventions will be combined with an educational web-application addressed to engage the adolescents through a learning-through-playing approach, using both educational materials and games. To assess the interventions, adherence to the MD, dietary records, physical activity, food frequency, sociodemographic, and quality of life questionnaires as well as classical anthropometric and biochemical parameters will be evaluated. Furthermore, an omics approach will be performed to elucidate whether the interventions can shape the gut microbiota and gut-derived metabolites to gain knowledge on the mechanisms through which the MD can exert its beneficial effects.MDPI AG2021-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/104651http://hdl.handle.net/10316/104651https://doi.org/10.3390/ijerph18094841eng1660-4601Boqué, NoemiTarro, LucíaRosi, AliceTorrell, HelenaSaldaña, GuillermoLuengo, ElisaRachman, ZeevPires, AntónioTavares, Nuno TiagoPires, Ana SaloméBotelho, Maria FilomenaMena, PedroScazzina, FrancescaDel Rio, DanieleCaimari, Antoniinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-01-24T21:56:31Zoai:estudogeral.uc.pt:10316/104651Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:21:19.720323Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
title |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
spellingShingle |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study Boqué, Noemi adolescents youth obesity Mediterranean diet cardiovascular risk factors educational approach healthy food products omics gut microbiota Adolescent Diet, Fat-Restricted Humans Italy Multicenter Studies as Topic Obesity Portugal Quality of Life Randomized Controlled Trials as Topic Spain Diet, Mediterranean |
title_short |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
title_full |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
title_fullStr |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
title_full_unstemmed |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
title_sort |
Study Protocol of a Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. a Traditional Low-Fat Diet in Adolescents: The MED4Youth Study |
author |
Boqué, Noemi |
author_facet |
Boqué, Noemi Tarro, Lucía Rosi, Alice Torrell, Helena Saldaña, Guillermo Luengo, Elisa Rachman, Zeev Pires, António Tavares, Nuno Tiago Pires, Ana Salomé Botelho, Maria Filomena Mena, Pedro Scazzina, Francesca Del Rio, Daniele Caimari, Antoni |
author_role |
author |
author2 |
Tarro, Lucía Rosi, Alice Torrell, Helena Saldaña, Guillermo Luengo, Elisa Rachman, Zeev Pires, António Tavares, Nuno Tiago Pires, Ana Salomé Botelho, Maria Filomena Mena, Pedro Scazzina, Francesca Del Rio, Daniele Caimari, Antoni |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Boqué, Noemi Tarro, Lucía Rosi, Alice Torrell, Helena Saldaña, Guillermo Luengo, Elisa Rachman, Zeev Pires, António Tavares, Nuno Tiago Pires, Ana Salomé Botelho, Maria Filomena Mena, Pedro Scazzina, Francesca Del Rio, Daniele Caimari, Antoni |
dc.subject.por.fl_str_mv |
adolescents youth obesity Mediterranean diet cardiovascular risk factors educational approach healthy food products omics gut microbiota Adolescent Diet, Fat-Restricted Humans Italy Multicenter Studies as Topic Obesity Portugal Quality of Life Randomized Controlled Trials as Topic Spain Diet, Mediterranean |
topic |
adolescents youth obesity Mediterranean diet cardiovascular risk factors educational approach healthy food products omics gut microbiota Adolescent Diet, Fat-Restricted Humans Italy Multicenter Studies as Topic Obesity Portugal Quality of Life Randomized Controlled Trials as Topic Spain Diet, Mediterranean |
description |
Youth obesity is a strong predictor of adult obesity, which has well-known negative health consequences. Thus, addressing adult obesity requires tackling youth obesity. MED4Youth's main objective is to strengthen the link between the Mediterranean Diet (MD) and the health benefits against youth obesity and associated cardiovascular disease (CVD) risk factors, identifying positive effects exerted by an MD including sourdough bread and healthy products from the Mediterranean basis (chickpeas/hummus, nuts, and pomegranate juice). For this purpose, a multicenter randomized controlled trial in which an MD-based intervention will be compared to a traditional low-fat diet intervention will be carried out with 240 overweight and obese adolescents (13-17 years) from Spain, Portugal, and Italy. Both interventions will be combined with an educational web-application addressed to engage the adolescents through a learning-through-playing approach, using both educational materials and games. To assess the interventions, adherence to the MD, dietary records, physical activity, food frequency, sociodemographic, and quality of life questionnaires as well as classical anthropometric and biochemical parameters will be evaluated. Furthermore, an omics approach will be performed to elucidate whether the interventions can shape the gut microbiota and gut-derived metabolites to gain knowledge on the mechanisms through which the MD can exert its beneficial effects. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/104651 http://hdl.handle.net/10316/104651 https://doi.org/10.3390/ijerph18094841 |
url |
http://hdl.handle.net/10316/104651 https://doi.org/10.3390/ijerph18094841 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1660-4601 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI AG |
publisher.none.fl_str_mv |
MDPI AG |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134104049942528 |