Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes

Detalhes bibliográficos
Autor(a) principal: Martins, Artur J.
Data de Publicação: 2015
Outros Autores: Bourbon, A. I., Vicente, A. A., Pinto, Susana, Lopes da Silva, J. A., Rocha, C. M. R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/35169
Resumo: Determination of material properties and functions is a crucial step towards optimization of fabrication methods as well as the development of electrospun nanofibers for use in e.g. food engineering applications. This work focused in evaluating physical and mass transfer properties of simple poly -caprolactone nanofibers (PCL membrane), and poly ε-caprolactone nanofibers with encapsulated trypsin (E-PCL membrane), in view of their future use in a catalytic filter reactor. PCL membranes registered high hydrophobicity values, while E-PCL membranes revealed stronger mechanical properties and an increase of mass due to water incorporation. A decrease of average pore size in the range of 30% to 40% was observed for E-PCL membranes and an average pore diameter of 1/3 of the size was registered when compared to the PCL membrane; this difference was shown to be significant enough to influence the transport of larger molecules (e.g. bovine serum albumin). Release experiments of active compounds (lysozyme, bovine serum albumin and lactoferrin) were successfully described by a model which accounts for both Fick and Case II transport the linear superimposition model. Results show that the transport mechanism is influenced by the type of active compound and by membranes physical properties.
id RCAP_f928f65ec24d81cfc5fe7f62f8ee3cad
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/35169
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranesNanofibersElectrospinningNanoencapsulationBiopolymerFick’s diffusionEngenharia e Tecnologia::NanotecnologiaEngenharia e Tecnologia::Biotecnologia IndustrialScience & TechnologyDetermination of material properties and functions is a crucial step towards optimization of fabrication methods as well as the development of electrospun nanofibers for use in e.g. food engineering applications. This work focused in evaluating physical and mass transfer properties of simple poly -caprolactone nanofibers (PCL membrane), and poly ε-caprolactone nanofibers with encapsulated trypsin (E-PCL membrane), in view of their future use in a catalytic filter reactor. PCL membranes registered high hydrophobicity values, while E-PCL membranes revealed stronger mechanical properties and an increase of mass due to water incorporation. A decrease of average pore size in the range of 30% to 40% was observed for E-PCL membranes and an average pore diameter of 1/3 of the size was registered when compared to the PCL membrane; this difference was shown to be significant enough to influence the transport of larger molecules (e.g. bovine serum albumin). Release experiments of active compounds (lysozyme, bovine serum albumin and lactoferrin) were successfully described by a model which accounts for both Fick and Case II transport the linear superimposition model. Results show that the transport mechanism is influenced by the type of active compound and by membranes physical properties.The present study was developed under the scope of the NanoBioCats project (PTDC/CTM-POL/112289/2009), funded by the Portuguese Science and Technology Foundation (Fundação para a Ciência e a Tecnologia – FCT). This work was also supported by the COMPETE program (funded by the European Union fund, FEDER under the framework of QREN (Programa Operacional Regional do Norte (ON.2 – O Novo Norte; FEDER))) through projects NORTE-07-0124-FEDER-000028 and NORTE-07-0124-FEDER-000069. Also, the authors thank Strategic Projects PEst-OE/EQB/LA0023/2013, PEst-C/EQB/LA0006/2013 – FCOMP-01-0124-FEDER-37285 and PEst-C/QUI/UI0062/2013 – FCOMP-01-0124-FEDER-037296. The Fundação para a Ciência e Tecnologia (FCT, Portugal) through grant SFRH/BD/73178/2010ElsevierUniversidade do MinhoMartins, Artur J.Bourbon, A. I.Vicente, A. A.Pinto, SusanaLopes da Silva, J. A.Rocha, C. M. R.2015-062015-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/35169engMartins, Artur J.; Bourbon, A. I.; Vicente, A. A.; Pinto, Susana; Lopes da Silva, J. A.; Rocha, C. M. R., Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes. Process Biochemistry, 50(6), 885-892, 20151359-511310.1016/j.procbio.2015.03.017http://www.sciencedirect.com/science/article/pii/S1359511315001580info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:07:35Zoai:repositorium.sdum.uminho.pt:1822/35169Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:58:36.820891Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
title Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
spellingShingle Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
Martins, Artur J.
Nanofibers
Electrospinning
Nanoencapsulation
Biopolymer
Fick’s diffusion
Engenharia e Tecnologia::Nanotecnologia
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
title_short Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
title_full Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
title_fullStr Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
title_full_unstemmed Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
title_sort Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes
author Martins, Artur J.
author_facet Martins, Artur J.
Bourbon, A. I.
Vicente, A. A.
Pinto, Susana
Lopes da Silva, J. A.
Rocha, C. M. R.
author_role author
author2 Bourbon, A. I.
Vicente, A. A.
Pinto, Susana
Lopes da Silva, J. A.
Rocha, C. M. R.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Martins, Artur J.
Bourbon, A. I.
Vicente, A. A.
Pinto, Susana
Lopes da Silva, J. A.
Rocha, C. M. R.
dc.subject.por.fl_str_mv Nanofibers
Electrospinning
Nanoencapsulation
Biopolymer
Fick’s diffusion
Engenharia e Tecnologia::Nanotecnologia
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
topic Nanofibers
Electrospinning
Nanoencapsulation
Biopolymer
Fick’s diffusion
Engenharia e Tecnologia::Nanotecnologia
Engenharia e Tecnologia::Biotecnologia Industrial
Science & Technology
description Determination of material properties and functions is a crucial step towards optimization of fabrication methods as well as the development of electrospun nanofibers for use in e.g. food engineering applications. This work focused in evaluating physical and mass transfer properties of simple poly -caprolactone nanofibers (PCL membrane), and poly ε-caprolactone nanofibers with encapsulated trypsin (E-PCL membrane), in view of their future use in a catalytic filter reactor. PCL membranes registered high hydrophobicity values, while E-PCL membranes revealed stronger mechanical properties and an increase of mass due to water incorporation. A decrease of average pore size in the range of 30% to 40% was observed for E-PCL membranes and an average pore diameter of 1/3 of the size was registered when compared to the PCL membrane; this difference was shown to be significant enough to influence the transport of larger molecules (e.g. bovine serum albumin). Release experiments of active compounds (lysozyme, bovine serum albumin and lactoferrin) were successfully described by a model which accounts for both Fick and Case II transport the linear superimposition model. Results show that the transport mechanism is influenced by the type of active compound and by membranes physical properties.
publishDate 2015
dc.date.none.fl_str_mv 2015-06
2015-06-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/35169
url http://hdl.handle.net/1822/35169
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Martins, Artur J.; Bourbon, A. I.; Vicente, A. A.; Pinto, Susana; Lopes da Silva, J. A.; Rocha, C. M. R., Physical and mass transfer properties of electrospun ε-polycaprolactone nanofiber membranes. Process Biochemistry, 50(6), 885-892, 2015
1359-5113
10.1016/j.procbio.2015.03.017
http://www.sciencedirect.com/science/article/pii/S1359511315001580
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132376946704384