Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,

Detalhes bibliográficos
Autor(a) principal: Lyra,Marcelo Rosandiski
Data de Publicação: 2021
Outros Autores: Sokoloski,Vanessa, de Macedo,Priscila Marques, Azevedo,Anna Carolina Procópio de
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200231
Resumo: Abstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.
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spelling Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,CryosurgeryItraconazolePotassium iodideSporothrixSporotrichosisAbstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.Sociedade Brasileira de Dermatologia2021-03-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200231Anais Brasileiros de Dermatologia v.96 n.2 2021reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2020.04.013info:eu-repo/semantics/openAccessLyra,Marcelo RosandiskiSokoloski,Vanessade Macedo,Priscila MarquesAzevedo,Anna Carolina Procópio deeng2021-05-04T00:00:00Zoai:scielo:S0365-05962021000200231Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2021-05-04T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
title Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
spellingShingle Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
Lyra,Marcelo Rosandiski
Cryosurgery
Itraconazole
Potassium iodide
Sporothrix
Sporotrichosis
title_short Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
title_full Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
title_fullStr Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
title_full_unstemmed Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
title_sort Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide,
author Lyra,Marcelo Rosandiski
author_facet Lyra,Marcelo Rosandiski
Sokoloski,Vanessa
de Macedo,Priscila Marques
Azevedo,Anna Carolina Procópio de
author_role author
author2 Sokoloski,Vanessa
de Macedo,Priscila Marques
Azevedo,Anna Carolina Procópio de
author2_role author
author
author
dc.contributor.author.fl_str_mv Lyra,Marcelo Rosandiski
Sokoloski,Vanessa
de Macedo,Priscila Marques
Azevedo,Anna Carolina Procópio de
dc.subject.por.fl_str_mv Cryosurgery
Itraconazole
Potassium iodide
Sporothrix
Sporotrichosis
topic Cryosurgery
Itraconazole
Potassium iodide
Sporothrix
Sporotrichosis
description Abstract Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200231
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200231
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.abd.2020.04.013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.96 n.2 2021
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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