Plasmacytoid dendritic cells in dermatology,

Detalhes bibliográficos
Autor(a) principal: Dias de Oliveira,Natasha Favoretto
Data de Publicação: 2021
Outros Autores: Santi,Claudia Giuli, Maruta,Celina Wakisaka, Aoki,Valeria
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000100076
Resumo: Abstract Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cells also exert a role as antigen-presenting cells, promote T-lymphocyte responses, immunoregulation, plasma cells differentiation and antibody secretion. Even though plasmacytoid dendritic cells are not usually present in normal skin, their presence is detected in healing processes, viral infections, and inflammatory, autoimmune, and neoplastic diseases. In recent years, the presence of plasmacytoid dendritic cells in several dermatological diseases has been described, enhancing their potential role in the pathogenesis of such conditions. Future studies on the role of plasmacytoid dendritic cells in dermatology may lead to new therapeutic targets.
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spelling Plasmacytoid dendritic cells in dermatology,Adaptive immunityDendritic cellsDermatological diseasesDermatologyInnate immunityAbstract Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cells also exert a role as antigen-presenting cells, promote T-lymphocyte responses, immunoregulation, plasma cells differentiation and antibody secretion. Even though plasmacytoid dendritic cells are not usually present in normal skin, their presence is detected in healing processes, viral infections, and inflammatory, autoimmune, and neoplastic diseases. In recent years, the presence of plasmacytoid dendritic cells in several dermatological diseases has been described, enhancing their potential role in the pathogenesis of such conditions. Future studies on the role of plasmacytoid dendritic cells in dermatology may lead to new therapeutic targets.Sociedade Brasileira de Dermatologia2021-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000100076Anais Brasileiros de Dermatologia v.96 n.1 2021reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2020.08.006info:eu-repo/semantics/openAccessDias de Oliveira,Natasha FavorettoSanti,Claudia GiuliMaruta,Celina WakisakaAoki,Valeriaeng2021-03-03T00:00:00Zoai:scielo:S0365-05962021000100076Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2021-03-03T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Plasmacytoid dendritic cells in dermatology,
title Plasmacytoid dendritic cells in dermatology,
spellingShingle Plasmacytoid dendritic cells in dermatology,
Dias de Oliveira,Natasha Favoretto
Adaptive immunity
Dendritic cells
Dermatological diseases
Dermatology
Innate immunity
title_short Plasmacytoid dendritic cells in dermatology,
title_full Plasmacytoid dendritic cells in dermatology,
title_fullStr Plasmacytoid dendritic cells in dermatology,
title_full_unstemmed Plasmacytoid dendritic cells in dermatology,
title_sort Plasmacytoid dendritic cells in dermatology,
author Dias de Oliveira,Natasha Favoretto
author_facet Dias de Oliveira,Natasha Favoretto
Santi,Claudia Giuli
Maruta,Celina Wakisaka
Aoki,Valeria
author_role author
author2 Santi,Claudia Giuli
Maruta,Celina Wakisaka
Aoki,Valeria
author2_role author
author
author
dc.contributor.author.fl_str_mv Dias de Oliveira,Natasha Favoretto
Santi,Claudia Giuli
Maruta,Celina Wakisaka
Aoki,Valeria
dc.subject.por.fl_str_mv Adaptive immunity
Dendritic cells
Dermatological diseases
Dermatology
Innate immunity
topic Adaptive immunity
Dendritic cells
Dermatological diseases
Dermatology
Innate immunity
description Abstract Plasmacytoid dendritic cells are part of the dendritic cells family and are a relevant link between innate and adaptive immunity. They are the most potent producers of type 1 interferon, generating antiviral response, stimulating macrophages and dendritic cells and inducing activation and migration of natural killer cells. Plasmacytoid dendritic cells also exert a role as antigen-presenting cells, promote T-lymphocyte responses, immunoregulation, plasma cells differentiation and antibody secretion. Even though plasmacytoid dendritic cells are not usually present in normal skin, their presence is detected in healing processes, viral infections, and inflammatory, autoimmune, and neoplastic diseases. In recent years, the presence of plasmacytoid dendritic cells in several dermatological diseases has been described, enhancing their potential role in the pathogenesis of such conditions. Future studies on the role of plasmacytoid dendritic cells in dermatology may lead to new therapeutic targets.
publishDate 2021
dc.date.none.fl_str_mv 2021-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000100076
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000100076
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.abd.2020.08.006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.96 n.1 2021
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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