Premature ovarian failure (POF) in Brazilian fragile X carriers
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 1999 |
| Outros Autores: | , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Genetics and Molecular Biology |
| Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000400002 |
Resumo: | The gynecological and reproductive histories of 193 women from fragile X families were surveyed. Among the 101 carriers of the premutation, 14 experienced premature menopause, contrarily to their 37 fully mutated and 55 noncarrier female relatives. Although premature menopause showed a tendency to cluster in certain fragile X families, as a group, the premutated women experienced menopause earlier than noncarriers. This suggests that premature menopause may be the extreme effect of a spectrum of ovarian anomalies associated with the fragile X premutation. |
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Premature ovarian failure (POF) in Brazilian fragile X carriersThe gynecological and reproductive histories of 193 women from fragile X families were surveyed. Among the 101 carriers of the premutation, 14 experienced premature menopause, contrarily to their 37 fully mutated and 55 noncarrier female relatives. Although premature menopause showed a tendency to cluster in certain fragile X families, as a group, the premutated women experienced menopause earlier than noncarriers. This suggests that premature menopause may be the extreme effect of a spectrum of ovarian anomalies associated with the fragile X premutation.Sociedade Brasileira de Genética1999-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000400002Genetics and Molecular Biology v.22 n.4 1999reponame:Genetics and Molecular Biologyinstname:Sociedade Brasileira de Genética (SBG)instacron:SBG10.1590/S1415-47571999000400002info:eu-repo/semantics/openAccessVianna-Morgante,Angela M.Costa,Silvia S.Pavanello,Rita de C.M.Otto,P.A.Mingroni-Netto,Regina C.eng2000-02-17T00:00:00Zoai:scielo:S1415-47571999000400002Revistahttp://www.gmb.org.br/ONGhttps://old.scielo.br/oai/scielo-oai.php||editor@gmb.org.br1678-46851415-4757opendoar:2000-02-17T00:00Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG)false |
| dc.title.none.fl_str_mv |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| title |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| spellingShingle |
Premature ovarian failure (POF) in Brazilian fragile X carriers Vianna-Morgante,Angela M. |
| title_short |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| title_full |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| title_fullStr |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| title_full_unstemmed |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| title_sort |
Premature ovarian failure (POF) in Brazilian fragile X carriers |
| author |
Vianna-Morgante,Angela M. |
| author_facet |
Vianna-Morgante,Angela M. Costa,Silvia S. Pavanello,Rita de C.M. Otto,P.A. Mingroni-Netto,Regina C. |
| author_role |
author |
| author2 |
Costa,Silvia S. Pavanello,Rita de C.M. Otto,P.A. Mingroni-Netto,Regina C. |
| author2_role |
author author author author |
| dc.contributor.author.fl_str_mv |
Vianna-Morgante,Angela M. Costa,Silvia S. Pavanello,Rita de C.M. Otto,P.A. Mingroni-Netto,Regina C. |
| description |
The gynecological and reproductive histories of 193 women from fragile X families were surveyed. Among the 101 carriers of the premutation, 14 experienced premature menopause, contrarily to their 37 fully mutated and 55 noncarrier female relatives. Although premature menopause showed a tendency to cluster in certain fragile X families, as a group, the premutated women experienced menopause earlier than noncarriers. This suggests that premature menopause may be the extreme effect of a spectrum of ovarian anomalies associated with the fragile X premutation. |
| publishDate |
1999 |
| dc.date.none.fl_str_mv |
1999-12-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000400002 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571999000400002 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S1415-47571999000400002 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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text/html |
| dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Genética |
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Sociedade Brasileira de Genética |
| dc.source.none.fl_str_mv |
Genetics and Molecular Biology v.22 n.4 1999 reponame:Genetics and Molecular Biology instname:Sociedade Brasileira de Genética (SBG) instacron:SBG |
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Sociedade Brasileira de Genética (SBG) |
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SBG |
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SBG |
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Genetics and Molecular Biology |
| collection |
Genetics and Molecular Biology |
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Genetics and Molecular Biology - Sociedade Brasileira de Genética (SBG) |
| repository.mail.fl_str_mv |
||editor@gmb.org.br |
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1752122377406251008 |