Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200014 |
Resumo: | A flow injection system using a tubular electrode based on the redox properties of copper (II) ions occluded in EVA membrane was developed for L-ascorbic acid determination. The poly-ethylene-co-vinyl acetate (EVA 40% m/m) matrix was doped with copper (II) ions and dispersed on the surface of a graphite/epoxy tubular electrode. The electrode showed a super-Nernstian response for L-ascorbic acid concentration between 10-3 and 10-1 mol L-1 with a detection limit of 8.5×10-4 mol L-1, when 0.1 mol L-1 KH2PO4 buffer mixed with 0.1 mol L-1 hydrogen peroxide at pH 5.0 was employed as carrier. The Potentiometric-FIA system allows an analytical frequency of 120 samples per hour with a precision of 3.6%. The results obtained for ascorbic acid determination in pharmaceutical samples, without any previous treatment, were similar to those obtained by the British Pharmacopoeia method. |
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Journal of the Brazilian Chemical Society (Online) |
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Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrodeL-ascorbic acid determinationtubular electrodeFIApharmaceutical samplesA flow injection system using a tubular electrode based on the redox properties of copper (II) ions occluded in EVA membrane was developed for L-ascorbic acid determination. The poly-ethylene-co-vinyl acetate (EVA 40% m/m) matrix was doped with copper (II) ions and dispersed on the surface of a graphite/epoxy tubular electrode. The electrode showed a super-Nernstian response for L-ascorbic acid concentration between 10-3 and 10-1 mol L-1 with a detection limit of 8.5×10-4 mol L-1, when 0.1 mol L-1 KH2PO4 buffer mixed with 0.1 mol L-1 hydrogen peroxide at pH 5.0 was employed as carrier. The Potentiometric-FIA system allows an analytical frequency of 120 samples per hour with a precision of 3.6%. The results obtained for ascorbic acid determination in pharmaceutical samples, without any previous treatment, were similar to those obtained by the British Pharmacopoeia method.Sociedade Brasileira de Química2000-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200014Journal of the Brazilian Chemical Society v.11 n.2 2000reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532000000200014info:eu-repo/semantics/openAccessFernandes,Julio Cesar B.Rover Jr.,LaércioKubota,Lauro T.Oliveira Neto,Graciliano deeng2000-10-23T00:00:00Zoai:scielo:S0103-50532000000200014Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2000-10-23T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
title |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
spellingShingle |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode Fernandes,Julio Cesar B. L-ascorbic acid determination tubular electrode FIA pharmaceutical samples |
title_short |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
title_full |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
title_fullStr |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
title_full_unstemmed |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
title_sort |
Potentiometric determination of L-ascorbic acid in pharmaceutical samples by FIA using a modified tubular electrode |
author |
Fernandes,Julio Cesar B. |
author_facet |
Fernandes,Julio Cesar B. Rover Jr.,Laércio Kubota,Lauro T. Oliveira Neto,Graciliano de |
author_role |
author |
author2 |
Rover Jr.,Laércio Kubota,Lauro T. Oliveira Neto,Graciliano de |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Fernandes,Julio Cesar B. Rover Jr.,Laércio Kubota,Lauro T. Oliveira Neto,Graciliano de |
dc.subject.por.fl_str_mv |
L-ascorbic acid determination tubular electrode FIA pharmaceutical samples |
topic |
L-ascorbic acid determination tubular electrode FIA pharmaceutical samples |
description |
A flow injection system using a tubular electrode based on the redox properties of copper (II) ions occluded in EVA membrane was developed for L-ascorbic acid determination. The poly-ethylene-co-vinyl acetate (EVA 40% m/m) matrix was doped with copper (II) ions and dispersed on the surface of a graphite/epoxy tubular electrode. The electrode showed a super-Nernstian response for L-ascorbic acid concentration between 10-3 and 10-1 mol L-1 with a detection limit of 8.5×10-4 mol L-1, when 0.1 mol L-1 KH2PO4 buffer mixed with 0.1 mol L-1 hydrogen peroxide at pH 5.0 was employed as carrier. The Potentiometric-FIA system allows an analytical frequency of 120 samples per hour with a precision of 3.6%. The results obtained for ascorbic acid determination in pharmaceutical samples, without any previous treatment, were similar to those obtained by the British Pharmacopoeia method. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200014 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532000000200014 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.11 n.2 2000 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318163860389888 |