Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000300447 |
Resumo: | The essential w-3 and w-6 fatty acids have important physiological functions, such as prevention of cardiovascular diseases and atherosclerosis, and are commercially sold as fish oil capsules. In the present work, a method previously described in the literature, based on the derivatization of polyunsaturated fatty acids and their gas chromatography-mass spectrometry (GC-MS) analysis in the form of methyl esters, was partially modified and optimized for determination of w-3 and w-6 fatty acids in fish oil capsules. In addition, the w-9 fatty acid oleic acid was also determined with the optimized method, despite the lack of information about its quantities in the acquired products. The method exhibited good linearity and precision, limits of detection and quantification in the ranges from 0.16 to 0.18 mg g-1 and 0.46 to 0.63 mg g-1, respectively, and recoveries above 76%. The method was applied to analyze ten brands of encapsulated fish oil marketed in Salvador, BA, Brazil. Amongst the results, it was shown that one brand had significantly high amounts of linoleic acid, which indicates a probable adulteration of the product. |
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Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahiafish oilw-3 and w-6 supplementscommercial brandsfatty acids contentGC-MS analysisThe essential w-3 and w-6 fatty acids have important physiological functions, such as prevention of cardiovascular diseases and atherosclerosis, and are commercially sold as fish oil capsules. In the present work, a method previously described in the literature, based on the derivatization of polyunsaturated fatty acids and their gas chromatography-mass spectrometry (GC-MS) analysis in the form of methyl esters, was partially modified and optimized for determination of w-3 and w-6 fatty acids in fish oil capsules. In addition, the w-9 fatty acid oleic acid was also determined with the optimized method, despite the lack of information about its quantities in the acquired products. The method exhibited good linearity and precision, limits of detection and quantification in the ranges from 0.16 to 0.18 mg g-1 and 0.46 to 0.63 mg g-1, respectively, and recoveries above 76%. The method was applied to analyze ten brands of encapsulated fish oil marketed in Salvador, BA, Brazil. Amongst the results, it was shown that one brand had significantly high amounts of linoleic acid, which indicates a probable adulteration of the product.Sociedade Brasileira de Química2020-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000300447Journal of the Brazilian Chemical Society v.31 n.3 2020reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0103-5053.20190203info:eu-repo/semantics/openAccessBrotas,Milena S. C.Carvalho,Graziele A.Pereira,Pedro A. P.eng2020-02-27T00:00:00Zoai:scielo:S0103-50532020000300447Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2020-02-27T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
title |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
spellingShingle |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia Brotas,Milena S. C. fish oil w-3 and w-6 supplements commercial brands fatty acids content GC-MS analysis |
title_short |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
title_full |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
title_fullStr |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
title_full_unstemmed |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
title_sort |
Determination, through Derivatization and GC-MS Analysis, of Omega-3 and Omega-6 Fatty Acids in Fish Oil Capsules Sold in Salvador, Bahia |
author |
Brotas,Milena S. C. |
author_facet |
Brotas,Milena S. C. Carvalho,Graziele A. Pereira,Pedro A. P. |
author_role |
author |
author2 |
Carvalho,Graziele A. Pereira,Pedro A. P. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Brotas,Milena S. C. Carvalho,Graziele A. Pereira,Pedro A. P. |
dc.subject.por.fl_str_mv |
fish oil w-3 and w-6 supplements commercial brands fatty acids content GC-MS analysis |
topic |
fish oil w-3 and w-6 supplements commercial brands fatty acids content GC-MS analysis |
description |
The essential w-3 and w-6 fatty acids have important physiological functions, such as prevention of cardiovascular diseases and atherosclerosis, and are commercially sold as fish oil capsules. In the present work, a method previously described in the literature, based on the derivatization of polyunsaturated fatty acids and their gas chromatography-mass spectrometry (GC-MS) analysis in the form of methyl esters, was partially modified and optimized for determination of w-3 and w-6 fatty acids in fish oil capsules. In addition, the w-9 fatty acid oleic acid was also determined with the optimized method, despite the lack of information about its quantities in the acquired products. The method exhibited good linearity and precision, limits of detection and quantification in the ranges from 0.16 to 0.18 mg g-1 and 0.46 to 0.63 mg g-1, respectively, and recoveries above 76%. The method was applied to analyze ten brands of encapsulated fish oil marketed in Salvador, BA, Brazil. Amongst the results, it was shown that one brand had significantly high amounts of linoleic acid, which indicates a probable adulteration of the product. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000300447 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000300447 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21577/0103-5053.20190203 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.31 n.3 2020 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
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1750318182630948864 |