Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography

Detalhes bibliográficos
Autor(a) principal: Vilela,Fernanda Maria Pinto
Data de Publicação: 2011
Outros Autores: Fonseca,Yris Maria, Vicentini,Fabiana T. M. C., Fonseca,Maria José Vieira, Amaral,Maria da Penha Henriques do
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026
Resumo: An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention.
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spelling Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography3-benzophenoneoctylmethoxycinnamateoctylsalicylateAn analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026Química Nova v.34 n.5 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000500026info:eu-repo/semantics/openAccessVilela,Fernanda Maria PintoFonseca,Yris MariaVicentini,Fabiana T. M. C.Fonseca,Maria José VieiraAmaral,Maria da Penha Henriques doeng2011-07-18T00:00:00Zoai:scielo:S0100-40422011000500026Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-07-18T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
title Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
spellingShingle Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
Vilela,Fernanda Maria Pinto
3-benzophenone
octylmethoxycinnamate
octylsalicylate
title_short Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
title_full Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
title_fullStr Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
title_full_unstemmed Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
title_sort Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
author Vilela,Fernanda Maria Pinto
author_facet Vilela,Fernanda Maria Pinto
Fonseca,Yris Maria
Vicentini,Fabiana T. M. C.
Fonseca,Maria José Vieira
Amaral,Maria da Penha Henriques do
author_role author
author2 Fonseca,Yris Maria
Vicentini,Fabiana T. M. C.
Fonseca,Maria José Vieira
Amaral,Maria da Penha Henriques do
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Vilela,Fernanda Maria Pinto
Fonseca,Yris Maria
Vicentini,Fabiana T. M. C.
Fonseca,Maria José Vieira
Amaral,Maria da Penha Henriques do
dc.subject.por.fl_str_mv 3-benzophenone
octylmethoxycinnamate
octylsalicylate
topic 3-benzophenone
octylmethoxycinnamate
octylsalicylate
description An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-40422011000500026
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.34 n.5 2011
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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