Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026 |
Resumo: | An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention. |
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Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography3-benzophenoneoctylmethoxycinnamateoctylsalicylateAn analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention.Sociedade Brasileira de Química2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026Química Nova v.34 n.5 2011reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422011000500026info:eu-repo/semantics/openAccessVilela,Fernanda Maria PintoFonseca,Yris MariaVicentini,Fabiana T. M. C.Fonseca,Maria José VieiraAmaral,Maria da Penha Henriques doeng2011-07-18T00:00:00Zoai:scielo:S0100-40422011000500026Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2011-07-18T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
title |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
spellingShingle |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography Vilela,Fernanda Maria Pinto 3-benzophenone octylmethoxycinnamate octylsalicylate |
title_short |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
title_full |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
title_fullStr |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
title_full_unstemmed |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
title_sort |
Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography |
author |
Vilela,Fernanda Maria Pinto |
author_facet |
Vilela,Fernanda Maria Pinto Fonseca,Yris Maria Vicentini,Fabiana T. M. C. Fonseca,Maria José Vieira Amaral,Maria da Penha Henriques do |
author_role |
author |
author2 |
Fonseca,Yris Maria Vicentini,Fabiana T. M. C. Fonseca,Maria José Vieira Amaral,Maria da Penha Henriques do |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Vilela,Fernanda Maria Pinto Fonseca,Yris Maria Vicentini,Fabiana T. M. C. Fonseca,Maria José Vieira Amaral,Maria da Penha Henriques do |
dc.subject.por.fl_str_mv |
3-benzophenone octylmethoxycinnamate octylsalicylate |
topic |
3-benzophenone octylmethoxycinnamate octylsalicylate |
description |
An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies. The effect of the vehicle on the skin retention of these filters was investigated. HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration. The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation. Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone showed the highest skin retention. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500026 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422011000500026 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.34 n.5 2011 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318112229556224 |