Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release

Detalhes bibliográficos
Autor(a) principal: Polonini,Hudson C.
Data de Publicação: 2014
Outros Autores: Soldati,Pedro Paulo, Oliveira,Marcone Augusto Leal de, Brandão,Marcos Antônio F., Chaves,Maria das Graças M., Raposo,Nádia R. B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Química Nova (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023
Resumo: In vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids.
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spelling Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug releasein vitro dug releasetransdermal steroidssemi-solid formulationsIn vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023Química Nova v.37 n.4 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140116info:eu-repo/semantics/openAccessPolonini,Hudson C.Soldati,Pedro PauloOliveira,Marcone Augusto Leal deBrandão,Marcos Antônio F.Chaves,Maria das Graças M.Raposo,Nádia R. B.eng2014-05-29T00:00:00Zoai:scielo:S0100-40422014000400023Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-05-29T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
title Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
spellingShingle Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
Polonini,Hudson C.
in vitro dug release
transdermal steroids
semi-solid formulations
title_short Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
title_full Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
title_fullStr Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
title_full_unstemmed Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
title_sort Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
author Polonini,Hudson C.
author_facet Polonini,Hudson C.
Soldati,Pedro Paulo
Oliveira,Marcone Augusto Leal de
Brandão,Marcos Antônio F.
Chaves,Maria das Graças M.
Raposo,Nádia R. B.
author_role author
author2 Soldati,Pedro Paulo
Oliveira,Marcone Augusto Leal de
Brandão,Marcos Antônio F.
Chaves,Maria das Graças M.
Raposo,Nádia R. B.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Polonini,Hudson C.
Soldati,Pedro Paulo
Oliveira,Marcone Augusto Leal de
Brandão,Marcos Antônio F.
Chaves,Maria das Graças M.
Raposo,Nádia R. B.
dc.subject.por.fl_str_mv in vitro dug release
transdermal steroids
semi-solid formulations
topic in vitro dug release
transdermal steroids
semi-solid formulations
description In vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.5935/0100-4042.20140116
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Química Nova v.37 n.4 2014
reponame:Química Nova (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Química Nova (Online)
collection Química Nova (Online)
repository.name.fl_str_mv Química Nova (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv quimicanova@sbq.org.br
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