Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023 |
Resumo: | In vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids. |
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Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug releasein vitro dug releasetransdermal steroidssemi-solid formulationsIn vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids.Sociedade Brasileira de Química2014-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023Química Nova v.37 n.4 2014reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.5935/0100-4042.20140116info:eu-repo/semantics/openAccessPolonini,Hudson C.Soldati,Pedro PauloOliveira,Marcone Augusto Leal deBrandão,Marcos Antônio F.Chaves,Maria das Graças M.Raposo,Nádia R. B.eng2014-05-29T00:00:00Zoai:scielo:S0100-40422014000400023Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2014-05-29T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
title |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
spellingShingle |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release Polonini,Hudson C. in vitro dug release transdermal steroids semi-solid formulations |
title_short |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
title_full |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
title_fullStr |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
title_full_unstemmed |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
title_sort |
Transdermal formulations containing human sexual steroids: development and validation of methods and in vitro drug release |
author |
Polonini,Hudson C. |
author_facet |
Polonini,Hudson C. Soldati,Pedro Paulo Oliveira,Marcone Augusto Leal de Brandão,Marcos Antônio F. Chaves,Maria das Graças M. Raposo,Nádia R. B. |
author_role |
author |
author2 |
Soldati,Pedro Paulo Oliveira,Marcone Augusto Leal de Brandão,Marcos Antônio F. Chaves,Maria das Graças M. Raposo,Nádia R. B. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Polonini,Hudson C. Soldati,Pedro Paulo Oliveira,Marcone Augusto Leal de Brandão,Marcos Antônio F. Chaves,Maria das Graças M. Raposo,Nádia R. B. |
dc.subject.por.fl_str_mv |
in vitro dug release transdermal steroids semi-solid formulations |
topic |
in vitro dug release transdermal steroids semi-solid formulations |
description |
In vitro release of bioidentical hormones in four different liposomal transdermal emulsions (containing testosterone, progesterone, estradiol, or estradiol and estriol) was assessed. For this purpose, novel high-performance liquid chromatography methods were developed and validated in an eco-friendly manner and used to determine the in vitro release of such products. The methods were suitable for our intended goal, and the emulsions employed were found to be effective as transporting candidates for the efficient release of hormones in the transdermal delivery of human sexual steroids. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000400023 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.5935/0100-4042.20140116 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.37 n.4 2014 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318115873357824 |