Central H1 and H2 receptor participation in the control of water and salt intake in rats

Detalhes bibliográficos
Autor(a) principal: Magrani, Janeide
Data de Publicação: 2005
Outros Autores: Silva, Emilio de Castro e, Ramos, Ana Claudia, Athanazio, Rodrigo Abensur, Barbetta, Marcelo Campos, Fregoneze, Josmara Bartolomei
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6604
Resumo: Trabalho completo: acesso restrito, p. 233–243
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spelling Magrani, JaneideSilva, Emilio de Castro eRamos, Ana ClaudiaAthanazio, Rodrigo AbensurBarbetta, Marcelo CamposFregoneze, Josmara BartolomeiMagrani, JaneideSilva, Emilio de Castro eRamos, Ana ClaudiaAthanazio, Rodrigo AbensurBarbetta, Marcelo CamposFregoneze, Josmara Bartolomei2012-08-17T19:51:06Z20050031-9384http://www.repositorio.ufba.br/ri/handle/ri/6604v. 84, n. 2Trabalho completo: acesso restrito, p. 233–243The aim of the present study was to evaluate the participation of brain H1 and H2 histaminergic receptors on water and salt intake induced by water deprivation (24 h), furosemide-induced sodium depletion and central angiotensinergic pharmacological stimulation in rats. Third ventricle injections of the H1 and H2 receptor antagonists, mepyramine (50, 100, 200 and 400 nmol) and cimetidine (100, 200 and 400 nmol), were unable to modify water intake induced by water deprivation and sodium depletion. Salt intake elicited by water deprivation and sodium depletion was reduced by the central administration of mepyramine, while intracerebroventricular administration of cimetidine had no effect. Water and salt intake evoked by central angiotensinergic stimulation (10 ng) was diminished by third ventricle injections of both mepyramine and cimetidine. Inhibition of the ingestive behaviors observed here is not a result of any illness-like effect produced by the intracerebroventricular injections of the histaminergic antagonists used, as demonstrated by an avoidance test. It was also shown that third ventricle injections of these compounds were unable to modify the hedonic behavior that leads rats to drink a tasty saccharin solution. We conclude that central histaminergic receptors participate in the control of salt intake induced by distinct physiological and pharmacological stimuli.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-08-17T19:51:06Z No. of bitstreams: 1 (169).pdf: 523123 bytes, checksum: 7128a63f7c380e8b3de9a7e34499fcc0 (MD5)Made available in DSpace on 2012-08-17T19:51:06Z (GMT). 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dc.title.pt_BR.fl_str_mv Central H1 and H2 receptor participation in the control of water and salt intake in rats
dc.title.alternative.pt_BR.fl_str_mv Physiology & Behavior
title Central H1 and H2 receptor participation in the control of water and salt intake in rats
spellingShingle Central H1 and H2 receptor participation in the control of water and salt intake in rats
Magrani, Janeide
title_short Central H1 and H2 receptor participation in the control of water and salt intake in rats
title_full Central H1 and H2 receptor participation in the control of water and salt intake in rats
title_fullStr Central H1 and H2 receptor participation in the control of water and salt intake in rats
title_full_unstemmed Central H1 and H2 receptor participation in the control of water and salt intake in rats
title_sort Central H1 and H2 receptor participation in the control of water and salt intake in rats
author Magrani, Janeide
author_facet Magrani, Janeide
Silva, Emilio de Castro e
Ramos, Ana Claudia
Athanazio, Rodrigo Abensur
Barbetta, Marcelo Campos
Fregoneze, Josmara Bartolomei
author_role author
author2 Silva, Emilio de Castro e
Ramos, Ana Claudia
Athanazio, Rodrigo Abensur
Barbetta, Marcelo Campos
Fregoneze, Josmara Bartolomei
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Magrani, Janeide
Silva, Emilio de Castro e
Ramos, Ana Claudia
Athanazio, Rodrigo Abensur
Barbetta, Marcelo Campos
Fregoneze, Josmara Bartolomei
Magrani, Janeide
Silva, Emilio de Castro e
Ramos, Ana Claudia
Athanazio, Rodrigo Abensur
Barbetta, Marcelo Campos
Fregoneze, Josmara Bartolomei
description Trabalho completo: acesso restrito, p. 233–243
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2012-08-17T19:51:06Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6604
dc.identifier.issn.none.fl_str_mv 0031-9384
dc.identifier.number.pt_BR.fl_str_mv v. 84, n. 2
identifier_str_mv 0031-9384
v. 84, n. 2
url http://www.repositorio.ufba.br/ri/handle/ri/6604
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Elsevier
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