Antioxidant activity of the microalga Spirulina maxima

Detalhes bibliográficos
Autor(a) principal: Miranda, Maria da Pureza Spínola
Data de Publicação: 1998
Outros Autores: Cintra, R. G., Barros, S. B. M., Mancini Filho, J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6973
Resumo: p. 1075-1079
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spelling Miranda, Maria da Pureza SpínolaCintra, R. G.Barros, S. B. M.Mancini Filho, J.Miranda, Maria da Pureza SpínolaCintra, R. G.Barros, S. B. M.Mancini Filho, J.2012-10-17T12:11:35Z2012-10-17T12:11:35Z19981414-431Xhttp://www.repositorio.ufba.br/ri/handle/ri/6973v. 31, n. 8p. 1075-1079Spirulina maxima, which is used as a food additive, is a microalga rich in protein and other essential nutrients. Spirulina contains phenolic acids, tocopherols and ß-carotene which are known to exhibit antioxidant properties. The aim of the present study was to evaluate the antioxidant capacity of a Spirulina extract. The antioxidant activity of a methanolic extract of Spirulina was determined in vitro and in vivo. The in vitro antioxidant capacity was tested on a brain homogenate incubated with and without the extract at 37oC. The IC50 (concentration which causes a 50% reduction of oxidation) of the extract in this system was 0.18 mg/ml. The in vivo antioxidant capacity was evaluated in plasma and liver of animals receiving a daily dose of 5 mg for 2 and 7 weeks. Plasma antioxidant capacity was measured in brain homogenate incubated for 1 h at 37oC. The production of oxidized compounds in liver after 2 h of incubation at 37oC was measured in terms of thiobarbituric acid reactant substances (TBARS) in control and experimental groups. Upon treatment, the antioxidant capacity of plasma was 71% for the experimental group and 54% for the control group. Data from liver spontaneous peroxidation studies were not significantly different between groups. The amounts of phenolic acids, a-tocopherol and ß-carotene were determined in Spirulina extracts. The results obtained indicate that Spirulina provides some antioxidant protection for both in vitro and in vivo systems.Submitted by JURANDI DE SOUZA SILVA (jssufba@hotmail.com) on 2012-10-17T12:11:35Z No. of bitstreams: 1 __www.scielo.br_pdf_bjmbr_v31n8_3055c.pdf: 360255 bytes, checksum: 1c1909b253b7dcc63e7c8e1fa5492b82 (MD5)Made available in DSpace on 2012-10-17T12:11:35Z (GMT). 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dc.title.pt_BR.fl_str_mv Antioxidant activity of the microalga Spirulina maxima
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Medical and Biological Research
title Antioxidant activity of the microalga Spirulina maxima
spellingShingle Antioxidant activity of the microalga Spirulina maxima
Miranda, Maria da Pureza Spínola
microalgae
antioxidant activity
Spirulina maxima
phenolic compounds
ß-carotene
a-tocopherol
title_short Antioxidant activity of the microalga Spirulina maxima
title_full Antioxidant activity of the microalga Spirulina maxima
title_fullStr Antioxidant activity of the microalga Spirulina maxima
title_full_unstemmed Antioxidant activity of the microalga Spirulina maxima
title_sort Antioxidant activity of the microalga Spirulina maxima
author Miranda, Maria da Pureza Spínola
author_facet Miranda, Maria da Pureza Spínola
Cintra, R. G.
Barros, S. B. M.
Mancini Filho, J.
author_role author
author2 Cintra, R. G.
Barros, S. B. M.
Mancini Filho, J.
author2_role author
author
author
dc.contributor.author.fl_str_mv Miranda, Maria da Pureza Spínola
Cintra, R. G.
Barros, S. B. M.
Mancini Filho, J.
Miranda, Maria da Pureza Spínola
Cintra, R. G.
Barros, S. B. M.
Mancini Filho, J.
dc.subject.por.fl_str_mv microalgae
antioxidant activity
Spirulina maxima
phenolic compounds
ß-carotene
a-tocopherol
topic microalgae
antioxidant activity
Spirulina maxima
phenolic compounds
ß-carotene
a-tocopherol
description p. 1075-1079
publishDate 1998
dc.date.issued.fl_str_mv 1998
dc.date.accessioned.fl_str_mv 2012-10-17T12:11:35Z
dc.date.available.fl_str_mv 2012-10-17T12:11:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6973
dc.identifier.issn.none.fl_str_mv 1414-431X
dc.identifier.number.pt_BR.fl_str_mv v. 31, n. 8
identifier_str_mv 1414-431X
v. 31, n. 8
url http://www.repositorio.ufba.br/ri/handle/ri/6973
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0100-879X1998000800007
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
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instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
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reponame_str Repositório Institucional da UFBA
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